UNDERSTANDING PATHOPHYSIOLOGY
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1. Cellular Biology
2. Altered Cellular And Tissue Biology
3. The Cellular Environment: Fluids And Electrolytes, Acids And Bases
4. Genes And Genetic Diseases
5. Epigenetics And Disease
6. Genes, Environment–Lifestyle, And Common Diseases
7. Innate Immunity: Inflammation And Wound Healing
8. Adaptive Immunity
9. Alterations In Immunity And Inflammation
10. Infection
11. Stress And Disease
12. Biology, Clinical Manifestations, And Treatment Of Cancer
13. Alterations In Oxygen Transport
14. Alterations In Hemostasis And Coagulation
15. Alterations In White Blood Cell Function
16. Alterations In Cardiovascular Function
17. Shock, Sepsis, And Multiple Organ Dysfunction Syndrome
18. Alterations Of Pulmonary Function
19. Alterations Of Hormonal Regulation
20. Alterations Of Hematologic Function In Children
21. Alterations Of Cardiovascular Function In Children
22. Alterations Of Pulmonary Function In Children
23. Structure And Function Of The Neurologic System
24. Pain, Temperature, Sleep, And Sensory Function
25. Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function
26. Disorders Of The Central And Peripheral Nervous Systems And Neuromuscular Junction
27. Alterations Of Neurologic Function In Children
28. Structure And Function Of The Endocrine System
29. Mechanisms Of Hormonal Regulation
30. Alterations Of Endocrine Function
31. Alterations Of Renal And Urinary Tract Function
32. Alterations Of Digestive Function
33. Alterations Of Liver And Biliary Function
34. Alterations Of Musculoskeletal Function
35. Alterations Of Reproductive Function
,Chapter 1. Cellular Biology
Multiple Choice
1. A Student Is Observing A Cell Under The Microscope. It Is Observed To Have
Supercoiled Dna With Histones. Which Of The Following Would Also Be Observed By The
Student?
a. A Single Circular Chromosome
b. A Nucleus
c. Free-Floating Nuclear Material
d. No Organelles
Ans: B
The Cell Described Is A Eukaryotic Cell, So It Has Histones And A Supercoiled Dna Within Its
Nucleus; Thus, The Nucleus Should Be Observed. A Single Circular Chromosome Is
Characteristic Of Prokaryotic Cells, Which Do Not Have Histones. Free-Floating Nuclear
Material Describes A Prokaryotic Cell, Which Would Not Have A Distinct Nucleus. Eukaryotic
Cells Have Membrane- Bound Cellular Components Called Organelles. No Organelles Describe
A Prokaryotic Cell.
2. A Nurse Is Instructing The Staff About Cellular Functions. Which Cellular
Function Is The Nurse Describing When An Isolated Cell Absorbs Oxygen And Uses It
To Transform
Nutrients To Energy?
a. Metabolic Absorption
b. Communication
c. Secretion
d. Respiration
Ans: D
, The Ability Of The Cell To Absorb Oxygen Refers To The Cells Function Of Respiration. The
Ability Of The Cell To Function Within A Society Of Cells Refers To Its Function Of
Communication. The Ability Of The Cell To Take In Nutrients Refers To The Cells Function
Of Metabolic Absorption.The Ability Of The Cell To Synthesize New Substances And Secrete
These Elsewhere Refers To The Cells Function Of Secretion.
3. A Eukaryotic Cell Is Undergoing Dna Replication. In Which Region Of The Cell
Would Most Of The Genetic Information Be Contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
Ans: C
The Region Of The Cell That Contains Genetic Material, Including A Large Amount Of
Ribonucleic Acid, Most Of The Dna, And Dna-Binding Proteins, Is The Nucleolus. The
Mitochondria Is The Site Of Cellular Respiration. The Ribosomes Are Involved In The
Manufacturing Of Proteins Within The Cell. The Nucleus Contains The Nucleolus, And It Is
The Nucleolus That Contains Genetic Material.
4. The Fluid-Mosaic Model For Biologic Membranes Describes Membrane
Behavior. According To This Model, Which Of The Following Float Singly Or As
Aggregates In The Fluid Lipid Bilayer?
a. Peripheral Membrane Proteins
b. Integral Membrane Proteins
c. Glycoproteins
d. Cell Adhesion Molecules
Ans: B
Integral Membrane Proteins Float Freely In The Fluid Lipid Bilayer. Peripheral Membrane
Proteins Are Not Embedded In The Layer, But Reside At The Surface. Glycoproteins Act As