MMSC490 FINAL EXAM | 211 QUESTIONS | WITH
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The eukaryotic cell cycle is composed of four phases in the following order:
a. G1; S; G2; M
b. G1; G2; S; M
c. G1; M; G2; S
d. S; G1; G2; M
Ans: A
The length of time it takes for the cells labeled during DNA synthesis to begin to
enter mitosis is a good estimate of the length of the _______ phase(s).
a. G1
b. S
c. G2
d. M
Ans: C
In a typical cycling mammalian cell, _______ of the cell cycle is spent in
interphase.
a. 99%
b. 95%
c. 75%
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d. 50%
Ans: B
Cell cycles of early embryonic animal cells are unusual because they have
a. no G1 or G2.
b. an elongated G1 and G2.
c. a short S.
d. a much shortened M.
Ans: A
The number of cells in the different phases of a population can be determined
most easily by using a(n) _______ to measure the amount of DNA per cell in a
large sample of cells.
a. scintillation counter
b. flow cytometer
c. fluorescence microscope
d. phase-contrast microscope after autoradiography
Ans: B
Which of the following represents the amount of DNA in a typical G2 cell?
a. n
b. 2n
c. 4n
d. 8n
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Ans: C
The G1 checkpoint in budding yeast cells is called
a. START.
b. the restriction point.
c. the decision point.
d. the G1/S boundary.
Ans: A
The G1 checkpoint in animal cells is called
a. START.
b. the restriction point.
c. the decision point.
d. the G1/S boundary.
Ans: B
Skin fibroblasts arrested in G0 are stimulated near a wound to enter G1 by
_______ growth factor.
a. epidermal
b. fibroblast
c. platelet-derived
d. keratinocyte
Ans: C
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The G2 checkpoint prevents entry into _______ if _______.
a. G1; DNA synthesis is not complete and/or DNA is damaged
b. S; DNA synthesis is not complete and/or DNA is damaged
c. G2; DNA synthesis is not complete and/or DNA is damaged
d. M; DNA synthesis is not complete and/or DNA is damaged
Ans: D
Maturation promotion factor (MPF), discovered by Masui and Markert, is the
factor that
a. is missing in the cdc2 mutant in yeast.
b. induces entry into meiosis when injected into frog oocytes.
c. fluctuates in amount during early cleavages of sea urchin eggs.
d. fluctuates in amount during the cell cycle of mammalian cells.
Ans: B
MPF is a
a. monomeric protein kinase.
b. dimer of two molecules of Cdk1.
c. dimer of Cdk1 and cyclin A.
d. dimer of Cdk1 and cyclin B.
Ans: D
MPF is a general regulator of the transition from
a. G1 to S.
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