NBME Pathology Practice Exam Guide Questions/Answer GUARANTEE A+
2025/2026
ERB-B2: what is it - Proto-oncogene
ERB-B2: cancer association - Breast Carcinoma
RAS: what is it - Proto-oncogene
N-MYC: what is it - Proto-oncogene
N-MYC: cancer assocication - Neuroblastoma
RET: what is it - Proto-oncogene
RET: cancer assocation - Men IIa/IIb
APC: what is it - Tumor Supressor Gene
APC: cancer association - Familial polyposis
APC: chromosome - 5
BRCA1/BRCA2: what is it - Tumor Supressor Gene
BRCA1/BRCA2: cancer association - Breast, ovary, prostate
BRCA1/BRCA2: chromosomes - 17 and 13 respectively
RB: what is it - Tumor Supressor Gene
RB: cancer associations (3) - Retinoblastoma, osteogenic sarcoma, breast
RB: chromosome - 13
P53: what is it - Tumor Supressor Gene
P53: cancer association - Li-Fraumeni syndrome
P53: chromosome - 17
, VHL: what is it - Tumor Supressor Gene
VHL: cancer association - Von Hippel-Lindau syndrome
VHL: chromosome - 3
WT1: what is it - Tumor Supressor Gene
WT1: cancer association - Wilms Tumor
WT1: chromosome - 11
Aflatoxin cancer assocation - Hepatocellular carcinoma when Hep B
present
Alcohol cancer assocations (3) - Squamous cell carcinoma of oropharynx
and upper/middle esophagus; pancreatic and hepatocellular carcinoma
Alkylating agents cancer assocation - Malignant lymphoma
Arsenic cancer associations (3) - squamous cell carcinoma of skin, lung
cancer, liver angiosarcoma
Asbestos cancer assocation (2) - Bronchogenic carcinoma, pleural
mesothelioma
Benzene cancer assocation - acute leukemia
Beryllium cancer assocation - Bronchogenic carcinoma
Chromium cancer assocation - Bronchogenic carcinoma
Cyclophosphamide cancer assocation - Transitional cell carcinoma of
bladder
β-Naphthylamine (aniline dyes) cancer assocation - transitional cell
carcinoma of bladder
Nickel cancer association - Bronchogenic carcinoma
2025/2026
ERB-B2: what is it - Proto-oncogene
ERB-B2: cancer association - Breast Carcinoma
RAS: what is it - Proto-oncogene
N-MYC: what is it - Proto-oncogene
N-MYC: cancer assocication - Neuroblastoma
RET: what is it - Proto-oncogene
RET: cancer assocation - Men IIa/IIb
APC: what is it - Tumor Supressor Gene
APC: cancer association - Familial polyposis
APC: chromosome - 5
BRCA1/BRCA2: what is it - Tumor Supressor Gene
BRCA1/BRCA2: cancer association - Breast, ovary, prostate
BRCA1/BRCA2: chromosomes - 17 and 13 respectively
RB: what is it - Tumor Supressor Gene
RB: cancer associations (3) - Retinoblastoma, osteogenic sarcoma, breast
RB: chromosome - 13
P53: what is it - Tumor Supressor Gene
P53: cancer association - Li-Fraumeni syndrome
P53: chromosome - 17
, VHL: what is it - Tumor Supressor Gene
VHL: cancer association - Von Hippel-Lindau syndrome
VHL: chromosome - 3
WT1: what is it - Tumor Supressor Gene
WT1: cancer association - Wilms Tumor
WT1: chromosome - 11
Aflatoxin cancer assocation - Hepatocellular carcinoma when Hep B
present
Alcohol cancer assocations (3) - Squamous cell carcinoma of oropharynx
and upper/middle esophagus; pancreatic and hepatocellular carcinoma
Alkylating agents cancer assocation - Malignant lymphoma
Arsenic cancer associations (3) - squamous cell carcinoma of skin, lung
cancer, liver angiosarcoma
Asbestos cancer assocation (2) - Bronchogenic carcinoma, pleural
mesothelioma
Benzene cancer assocation - acute leukemia
Beryllium cancer assocation - Bronchogenic carcinoma
Chromium cancer assocation - Bronchogenic carcinoma
Cyclophosphamide cancer assocation - Transitional cell carcinoma of
bladder
β-Naphthylamine (aniline dyes) cancer assocation - transitional cell
carcinoma of bladder
Nickel cancer association - Bronchogenic carcinoma
