Advanced Pharmacology Final Exam
Location of H4 receptors -
predominantly found on eosinophils, neutrophils, and T cells
second generation antihistamine that cannot be removed hemodialysis -
cetirizine (Zyrtec)
Dx of enterobiasis -
Perianal swab using adhesive tape that is examined microscopically for eggs
treatment modalities of tuberculosis -
directly observed therapy to ensure adherence to drug regimen with any frequency less
than daily dosing
extended use of aminoglycosides increases risk for infection by which of pathogens? -
c.difficile - associated diarrhea and pseudomembranous colitis with extended use
mode of administration of dactinomycin -
vesicants --> administered only by the intravenous route to prevent extravasation
FDA approved indication for methotrexate -
meningeal leukemia
trophoblastic neoplasms
breast cancer
synthetic muscarinic receptor antagonist that possesses M3 receptor selectivity -
darifenacin
solifenacin
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, autonomic agents associated stimulation of insulin production, increase glycogenolysis in the liver,
and complicate the management of DM? -
alpha adrenergic agonists
midodrine
phenylephrine
clonidine
guanabenz
methyldopa
most commonly used therapy for iron-deficiency anemia -
ferrous sulfate
fatalities have occurred with the test dose of which drug? -
iron dextran
antilipemic agent that target triglycerides -
Fibrates (e.g. gemfibrozil)
mechanism of action of calcium-channel blocking agents -
primarily act on the calcium channels in the large vessels to produce vasodilation and
subsequent reducing in blood pressure
Nifedipine --- for arterial vessels
Amlodipine --- produce less reflex tachycardia than nifedipine, used for pt with HF
Felodipine --- vascular tissue
Nicardipine --- for cerebral and coronary vessels
Hypotensive agent FDA approved for treatment of ADHD -
Extended release guanfacine
used for children aged 6-17 years who have ADHD
2|Page
Location of H4 receptors -
predominantly found on eosinophils, neutrophils, and T cells
second generation antihistamine that cannot be removed hemodialysis -
cetirizine (Zyrtec)
Dx of enterobiasis -
Perianal swab using adhesive tape that is examined microscopically for eggs
treatment modalities of tuberculosis -
directly observed therapy to ensure adherence to drug regimen with any frequency less
than daily dosing
extended use of aminoglycosides increases risk for infection by which of pathogens? -
c.difficile - associated diarrhea and pseudomembranous colitis with extended use
mode of administration of dactinomycin -
vesicants --> administered only by the intravenous route to prevent extravasation
FDA approved indication for methotrexate -
meningeal leukemia
trophoblastic neoplasms
breast cancer
synthetic muscarinic receptor antagonist that possesses M3 receptor selectivity -
darifenacin
solifenacin
1|Page
, autonomic agents associated stimulation of insulin production, increase glycogenolysis in the liver,
and complicate the management of DM? -
alpha adrenergic agonists
midodrine
phenylephrine
clonidine
guanabenz
methyldopa
most commonly used therapy for iron-deficiency anemia -
ferrous sulfate
fatalities have occurred with the test dose of which drug? -
iron dextran
antilipemic agent that target triglycerides -
Fibrates (e.g. gemfibrozil)
mechanism of action of calcium-channel blocking agents -
primarily act on the calcium channels in the large vessels to produce vasodilation and
subsequent reducing in blood pressure
Nifedipine --- for arterial vessels
Amlodipine --- produce less reflex tachycardia than nifedipine, used for pt with HF
Felodipine --- vascular tissue
Nicardipine --- for cerebral and coronary vessels
Hypotensive agent FDA approved for treatment of ADHD -
Extended release guanfacine
used for children aged 6-17 years who have ADHD
2|Page
