Biochemistry
Hemoglobin, Myoglobin And Oxygen Transport
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VIII pages
1. Functions of globular proteins (5)
Storage of ions and other moleculesTransport of Ions and molecules Defense against pathogens Muscle
2. Do proteins bind with ligands through irreversible reactions or reversible?
Reversible
3. Are binding sites specific to each ligand?
Yes
4. What is ligand binding coupled to conformational changes called?
Induced fit
5. What is it called when conformational changes in one subunit can affect the others
Cooperativity
6. Are the interactions in binding sites with ligand covalent bonds?
No, the bonds are non covalent
7. Do ligands typically bind on the surface of a protein?
No they typically find their binding sites in cavities
8. Model of specificity ligand binding?
Lock and key modelInduced fit
9. What are the 4 characteristics of complementarity of the ligand and binding site?
SizeShapeChargeHydrophobic/hydrophilic character
10. What is induced fit?
When ligand bind to protein there is a conformational change
11. What is lock and key?
Protein and ligand fit together perfectly
12. What are interactions between ligand and protein mediated by?
Induced fit
13. What can interactions between ligand and proteins regulated by?
Activator or inhibitor
14. What are things that induce change in protein conformation called?
They are allosteric
15. Can ligands help each other change the shape?
Yes it is comparitivity
16. How many subunit are myoglobin?
1
Biochemistry 2024/25 Edition
Hemoglobin, Myoglobin And Oxygen Transport
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VIII pages
1. Functions of globular proteins (5)
Storage of ions and other moleculesTransport of Ions and molecules Defense against pathogens Muscle
2. Do proteins bind with ligands through irreversible reactions or reversible?
Reversible
3. Are binding sites specific to each ligand?
Yes
4. What is ligand binding coupled to conformational changes called?
Induced fit
5. What is it called when conformational changes in one subunit can affect the others
Cooperativity
6. Are the interactions in binding sites with ligand covalent bonds?
No, the bonds are non covalent
7. Do ligands typically bind on the surface of a protein?
No they typically find their binding sites in cavities
8. Model of specificity ligand binding?
Lock and key modelInduced fit
9. What are the 4 characteristics of complementarity of the ligand and binding site?
SizeShapeChargeHydrophobic/hydrophilic character
10. What is induced fit?
When ligand bind to protein there is a conformational change
11. What is lock and key?
Protein and ligand fit together perfectly
12. What are interactions between ligand and protein mediated by?
Induced fit
13. What can interactions between ligand and proteins regulated by?
Activator or inhibitor
14. What are things that induce change in protein conformation called?
They are allosteric
15. Can ligands help each other change the shape?
Yes it is comparitivity
16. How many subunit are myoglobin?
1
Biochemistry 2024/25 Edition
