Rafi Haematology- Questions & Answers
A 50-year-old male presents with exertional fatigue. He is otherwise well with no significant past
medical history and he is not on any medications. His blood results highlight the following
abnormal readings:
Hb 125 g/L 135-180 g/L
Calcium 2.9 mmol/L 2.1-2.6 mmol/L
The rest of the blood test results including mean corpuscular volume, platelet count and white
cell count are normal. Serum ferritin, vitamin B12 and folic acid level are also normal.
Urine protein electrophoresis is done and it reveals the presence of immunoglobulin light chains.
Which of the following is the most likely diagnosis?
Gout
Megaloblastic anaemia
Multiple myeloma
Non-Hodgkin lymphoma
Acute interstitial nephritis Correct Ans-Multiple myeloma
"
,A 43-year-old women is identified as being a carrier of a BRCA 1 mutation. Apart from breast
cancer, which of the following malignancies is she at greatest risk of developing?
Colonic cancer
Ovarian cancer
Follicular carcinoma of the thyroid
Pituitary adenoma
Phaeochromocytoma Correct Ans-Ovarian cancer
"
Which one of the following cellular types or features is not seen in sarcoidosis?
Reed Sternberg Cells
T lymphocytes
Macrophages
Asteroid bodies
B lymphocytes Correct Ans-Reed sternberg cells
"
An 18 year old woman is admitted to the Emergency Department following a motor vehicle
collision. The patient is hypotensive, blood pressure 90/40 mmHg and tachycardic, 120 beats per
minute, and has oxygen saturations of 92%. Initial resuscitation is commenced using one litre of
0.9% normal saline. The consultant is concerned that the spleen has ruptured. A cross match and
request of four units of blood has been sent to the haematology lab. The patient's sister overhears
,the conversation behind the curtain. She thinks she is blood group A because she donates blood
every year. What blood product can this patient receive until the cross match result is returned?
AB rhesus negative
O rhesus negative
O rhesus positive
AB rhesus positive
A rhesus positive Correct Ans-O rhesus negative
"
A 30-year-old obese nulliparous lady has just delivered a live singleton and the placenta, but
continues to bleed profusely; the registrar estimates she has lost approximately 600 ml of blood.
She has been given both crystalloid and colloids, but is still haemodynamically unstable.
Assuming crossmatched blood is not yet available and her blood group is unknown, which blood
group should be administered in order to avoid a mismatched transfusion?
O negative
O positive
AB negative
AB positive
A negative Correct Ans-O negative
"
, You are the medical student in a general surgical team. An 84-year-old female is awaiting a
mastectomy for breast cancer. What is the most common type of breast cancer?
Invasive lobular carcinoma
Tubular carcinoma
Invasive ductal carcinoma
Paget's disease
Medullary carcinoma Correct Ans-Invasive ductal carcinoma
"
A 26-year-old man presents to his physician for a health check prior to his upcoming
participation in the regional 20-mile cycling race. He has been preparing for over a year and is
very keen to come first. He has experienced occasional bilateral headaches for the past 3 weeks
that come and go and are not associated with aura, photophobia or phonophobia. He has some
localized erythema on his abdomen which is slightly tender on palpation but no masses are felt.
His bowel and bladder function are normal. He had flu-like symptoms last week but feels much
better now. His blood results are shown below, and his haematocrit value is raised above normal.
Hb 198 g/l
Platelets 250 * 109/l
WBC 6 * 109/l
Which of the following explain his symptoms and blood results.
A 50-year-old male presents with exertional fatigue. He is otherwise well with no significant past
medical history and he is not on any medications. His blood results highlight the following
abnormal readings:
Hb 125 g/L 135-180 g/L
Calcium 2.9 mmol/L 2.1-2.6 mmol/L
The rest of the blood test results including mean corpuscular volume, platelet count and white
cell count are normal. Serum ferritin, vitamin B12 and folic acid level are also normal.
Urine protein electrophoresis is done and it reveals the presence of immunoglobulin light chains.
Which of the following is the most likely diagnosis?
Gout
Megaloblastic anaemia
Multiple myeloma
Non-Hodgkin lymphoma
Acute interstitial nephritis Correct Ans-Multiple myeloma
"
,A 43-year-old women is identified as being a carrier of a BRCA 1 mutation. Apart from breast
cancer, which of the following malignancies is she at greatest risk of developing?
Colonic cancer
Ovarian cancer
Follicular carcinoma of the thyroid
Pituitary adenoma
Phaeochromocytoma Correct Ans-Ovarian cancer
"
Which one of the following cellular types or features is not seen in sarcoidosis?
Reed Sternberg Cells
T lymphocytes
Macrophages
Asteroid bodies
B lymphocytes Correct Ans-Reed sternberg cells
"
An 18 year old woman is admitted to the Emergency Department following a motor vehicle
collision. The patient is hypotensive, blood pressure 90/40 mmHg and tachycardic, 120 beats per
minute, and has oxygen saturations of 92%. Initial resuscitation is commenced using one litre of
0.9% normal saline. The consultant is concerned that the spleen has ruptured. A cross match and
request of four units of blood has been sent to the haematology lab. The patient's sister overhears
,the conversation behind the curtain. She thinks she is blood group A because she donates blood
every year. What blood product can this patient receive until the cross match result is returned?
AB rhesus negative
O rhesus negative
O rhesus positive
AB rhesus positive
A rhesus positive Correct Ans-O rhesus negative
"
A 30-year-old obese nulliparous lady has just delivered a live singleton and the placenta, but
continues to bleed profusely; the registrar estimates she has lost approximately 600 ml of blood.
She has been given both crystalloid and colloids, but is still haemodynamically unstable.
Assuming crossmatched blood is not yet available and her blood group is unknown, which blood
group should be administered in order to avoid a mismatched transfusion?
O negative
O positive
AB negative
AB positive
A negative Correct Ans-O negative
"
, You are the medical student in a general surgical team. An 84-year-old female is awaiting a
mastectomy for breast cancer. What is the most common type of breast cancer?
Invasive lobular carcinoma
Tubular carcinoma
Invasive ductal carcinoma
Paget's disease
Medullary carcinoma Correct Ans-Invasive ductal carcinoma
"
A 26-year-old man presents to his physician for a health check prior to his upcoming
participation in the regional 20-mile cycling race. He has been preparing for over a year and is
very keen to come first. He has experienced occasional bilateral headaches for the past 3 weeks
that come and go and are not associated with aura, photophobia or phonophobia. He has some
localized erythema on his abdomen which is slightly tender on palpation but no masses are felt.
His bowel and bladder function are normal. He had flu-like symptoms last week but feels much
better now. His blood results are shown below, and his haematocrit value is raised above normal.
Hb 198 g/l
Platelets 250 * 109/l
WBC 6 * 109/l
Which of the following explain his symptoms and blood results.
