Pharmacology Final Ivy Tech` Exam Study Guide Solutions

Pharmacology Final Ivy Tech` Exam Study Guide Solutions chloroquine - Ans:-Class: Antimalarial -oquine Action: Inhibits reproduction Use: Treats Malaria Adverse effects: -retinotherapy -hepatic dysfunction -incrased psoriasis exacerbation Interactions: ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 2/127 -Combination quinine=risk for cardiac toxicity & convulstions Interventions/Education: -take 1-2 weeks prior to travel; 4-6 weeks after -regular eye exams -monitor liver enzymes: AST/ALT -take with meals metronidazole - Ans:-Class: Antiprotozoal -azole Action: Inhibits protein synthesis Use: Treats amebiasis, trichonomiasis, and giardiasis Adverse effects: ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 3/127 -GI distress -Metallic taste -Dark, reddish brown urine -Superinfection (C-diff--watery stools) -headaches, dizziness Interactions: -No alcohol -Warfarin: increased risk of bleeding Interventions/Education: -Partner needs to be treated simultaneously -Evaluate stool specimen -Take w/food -Stop taking if Ataxia (loss of control of bodily movements) occurs ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 4/127 mebendazole - Ans:-Class: Antihelminthic -bendazole Action: Blocks glucose uptake Use: Treat worm infestation Adverse effects: -GI upset: Transient abdominal pain/diarrhea Interactions: -High fat meals interfere w/effectiveness Interventions/Education: -Take w/food (for GI upset) ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 5/127 -Vigilant Hygeine -Evaluate stool specimen -monitor for hepatotoxicity -twice daily for 3 days chlorambucil - Ans:-Class: Alkylating Agents -no stem Action: React chemically to damage DNA structure (alters it) Use: Most useful in treating slow-growing cancers Adverse effects: -Bone marrow suppression -Increased uric acid levels (pain) -CNS & tremors, confusion ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 6/127 -Alopecia -hepatotoxicity -secondary cancer -pallor -SOB Interactions: -none to know Interventions/Education: -PPE (carcinogenic) -Patient safety (tremors, confusion) -Allopurinol for uric acid (gout) -Monitor for anemia, leukopenia, throbocytopenia -Monitor for infection ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER 2024 Page 7/127 methoterexate - Ans:-Class: Antimetabolites -no stem Action: Inhibit folic acid role in DNA synthesis Use: Treatment of cancer (also used for lupus and RA) Adverse effects: -Bone marrow suppression -CNS effects (drowsiness, dizziness, fatigue)