BIOC 385 || with 100% Errorless Solutions.
In the Krebs bicycle, which of the following citrate cycle intermediates links to the urea cycle via
argininosuccinate? correct answers Fumarate
Which of the following is correct and most accurately describes the complete urea cycle of the
eukaryotic cell? correct answers The urea cycle occurs between the mitochondrial matrix and the
cytoplasm of the eukaryotic cell.
Which cellular change(s) would not encourage the Krebs bicycle and thus the probability of the
urea cycle taking place to completion? correct answers - increased aspartate charging to
mitochondrial tRNAs
- increased conversion of oxaloacetate into citrate
Isolate one polypeptide subunit of the ubiquitin structure by clicking the black-outlined box for
"a (amino)" or "b (amino)" on the bottom of the player screen. This will either display or remove
them from view. correct answers parallel Beta Sheets
When observing both ubiquitin polypeptides in this molecular structure that are covalently
bonded together, the covalent bond that leads to polyubiquitination is a bond between which two
residues? correct answers lysine & glycine
After covalent modification of a target protein with the ubiquitin that is shown in the molecular
structure, what is the most likely fate of the ubiquitin chain? correct answers The target protein,
without the polyubiquitin attachment, will be accepted into the proteasome and digested; ATP
will be consumed during this process. The ubiquitin concentration in the cytoplasm will remain
stable.
Other than the proteasome, there is a second organelle mechanism of protein degradation within
the eukaryotic cell. Which of the following organelles is also involved in protein degradation?
correct answers lysosome
Upon deamination of an amino acid, which component becomes substrate for the urea cycle?
correct answers ammonia
In a eukaryotic cell, deamination of amino acids takes place most extensively in the correct
answers mitochondrial matrix
Within the urea cycle, citrulline is produced by ornithine transcarbamylase in the
(mitochondria)
and is consumed in the
(cytoplasm) correct answers mitochondria, cytoplasm
Which pathway does NOT provide metabolic precursors for amino acid synthesis? correct
answers urea cycle
, Endothelial cells can receive a chemical signal from neurons. This signal is in the form of
neuronal (A) release. This chemical messenger binds to a membrane receptor that engages a
signal transduction pathway, which increases the cytoplasmic concentration of (B) ions. This
ionic secondary messenger then activates endothelial nitric oxide synthase. correct answers
acetylcholine, calcium
Reducing power from which of the following would help drive the nitric oxide synthase
reaction? correct answers pentose phosphate pathway
There are many diseases collectively called porphyrias that are characterized by the
accumulation of heme precursors in the blood and liver. Which type of porphyria is characterized
by low uroporphyrinogen III synthesis? correct answers congenital erythropoietic porphyria
In the duodenum, enteropeptidase correct answers cleaves trypsinogen to form trypsin
Which of the three proteins in the ubiquination pathway is the most responsible for recognizing
the ubiquintated target protein? correct answers E3
The shikimate pathway can be defined as the pathway that involves the correct answers
condensation of phosphoenolpyruvate and erythrose-4-phosphate.
What is the mechanism by which Roundup works? correct answers Glyphosate is a competitive
inhibitor to plant EPSP synthase.
It is important that proteolytic enzymes in the lysosome are optimized to work at low pH because
low pH correct answers enhances protein denaturing.
Why does it make sense that tadpoles (which live in water) have low levels of the enzyme
arginase, but after metamorphosis into frogs (which live on land), their arginase levels increase?
correct answers Tadpoles living in water can excrete ammonia directly, but once on land, they
need to excrete urea.
The two mechanisms to regulate protein ubiquitination are biochemical changes to correct
answers target proteins and E3 ligases.
In severe combined immunodeficiency disease (SCID), ribonucleotide reductase activity is
__________ because of an overabundance of __________. correct answers inhibited;dATP
In purines, __________ nitrogen atoms and __________ carbon atoms originate from glycine.
correct answers 1;2
15N-labeled aspartate is provided to bacteria during the biosynthesis of pyrimidine
trinucleotides. The radiolabeled nitrogen would ultimately be found in correct answers both UTP
& CTP
In the Krebs bicycle, which of the following citrate cycle intermediates links to the urea cycle via
argininosuccinate? correct answers Fumarate
Which of the following is correct and most accurately describes the complete urea cycle of the
eukaryotic cell? correct answers The urea cycle occurs between the mitochondrial matrix and the
cytoplasm of the eukaryotic cell.
Which cellular change(s) would not encourage the Krebs bicycle and thus the probability of the
urea cycle taking place to completion? correct answers - increased aspartate charging to
mitochondrial tRNAs
- increased conversion of oxaloacetate into citrate
Isolate one polypeptide subunit of the ubiquitin structure by clicking the black-outlined box for
"a (amino)" or "b (amino)" on the bottom of the player screen. This will either display or remove
them from view. correct answers parallel Beta Sheets
When observing both ubiquitin polypeptides in this molecular structure that are covalently
bonded together, the covalent bond that leads to polyubiquitination is a bond between which two
residues? correct answers lysine & glycine
After covalent modification of a target protein with the ubiquitin that is shown in the molecular
structure, what is the most likely fate of the ubiquitin chain? correct answers The target protein,
without the polyubiquitin attachment, will be accepted into the proteasome and digested; ATP
will be consumed during this process. The ubiquitin concentration in the cytoplasm will remain
stable.
Other than the proteasome, there is a second organelle mechanism of protein degradation within
the eukaryotic cell. Which of the following organelles is also involved in protein degradation?
correct answers lysosome
Upon deamination of an amino acid, which component becomes substrate for the urea cycle?
correct answers ammonia
In a eukaryotic cell, deamination of amino acids takes place most extensively in the correct
answers mitochondrial matrix
Within the urea cycle, citrulline is produced by ornithine transcarbamylase in the
(mitochondria)
and is consumed in the
(cytoplasm) correct answers mitochondria, cytoplasm
Which pathway does NOT provide metabolic precursors for amino acid synthesis? correct
answers urea cycle
, Endothelial cells can receive a chemical signal from neurons. This signal is in the form of
neuronal (A) release. This chemical messenger binds to a membrane receptor that engages a
signal transduction pathway, which increases the cytoplasmic concentration of (B) ions. This
ionic secondary messenger then activates endothelial nitric oxide synthase. correct answers
acetylcholine, calcium
Reducing power from which of the following would help drive the nitric oxide synthase
reaction? correct answers pentose phosphate pathway
There are many diseases collectively called porphyrias that are characterized by the
accumulation of heme precursors in the blood and liver. Which type of porphyria is characterized
by low uroporphyrinogen III synthesis? correct answers congenital erythropoietic porphyria
In the duodenum, enteropeptidase correct answers cleaves trypsinogen to form trypsin
Which of the three proteins in the ubiquination pathway is the most responsible for recognizing
the ubiquintated target protein? correct answers E3
The shikimate pathway can be defined as the pathway that involves the correct answers
condensation of phosphoenolpyruvate and erythrose-4-phosphate.
What is the mechanism by which Roundup works? correct answers Glyphosate is a competitive
inhibitor to plant EPSP synthase.
It is important that proteolytic enzymes in the lysosome are optimized to work at low pH because
low pH correct answers enhances protein denaturing.
Why does it make sense that tadpoles (which live in water) have low levels of the enzyme
arginase, but after metamorphosis into frogs (which live on land), their arginase levels increase?
correct answers Tadpoles living in water can excrete ammonia directly, but once on land, they
need to excrete urea.
The two mechanisms to regulate protein ubiquitination are biochemical changes to correct
answers target proteins and E3 ligases.
In severe combined immunodeficiency disease (SCID), ribonucleotide reductase activity is
__________ because of an overabundance of __________. correct answers inhibited;dATP
In purines, __________ nitrogen atoms and __________ carbon atoms originate from glycine.
correct answers 1;2
15N-labeled aspartate is provided to bacteria during the biosynthesis of pyrimidine
trinucleotides. The radiolabeled nitrogen would ultimately be found in correct answers both UTP
& CTP
