Lupus NCLEX Practice Questions with complete solutions

The nurse is preparing a presentation on systemic lupus erythematosus (SLE). Which statement should the nurse include? (Select all that apply.) A. The etiology is known to be linked to environmental factors. B. Manifestations can be mild to fatal, with remissions and exacerbations. C. The immune complex deposits trigger an inflammatory response. D. SLE is a result of deposition of antigen-antibody complexes in connective tissues. E. The inflammatory response leads to anaphylactic shock. B. Manifestations can be mild to fatal, with remissions and exacerbations. C. The immune complex deposits trigger an inflammatory response. D. SLE is a result of deposition of antigen-antibody complexes in connective tissues. The pathophysiology of systemic lupus erythematosus is a result of the formation of antigen-antibody immunocomplexes that are deposited in the connective tissue and trigger an inflammatory response. The manifestations of the disease can be mild to fatal, and remissions are followed by exacerbations. The inflammatory response leads to tissue damage but not anaphylactic shock (allergic reaction). Although the exact etiology of SLE is unknown, genetic, ethnic, environmental, and hormonal factors play a role in its development.