Maryville University NURS615 Pharmacology Exam 4 with Questions and Answers

Maryville University NURS615 Pharmacology Exam 4 with Questions and Answers What are examples of inhaled Short-acting Beta Agonists? (SABAs) ANSWER Albuterol and levabuterol What is the MOA of inhaled beta agonists? ANSWER To relax airway smooth muscle by increasing cyclic cAMP; dilation and opening of airway What is the use of inhaled beta agonists? ANSWER Used in bronchospasm associated with: asthma, bronchitis, and COPD When are SABAs used (albuterol and levabuterol)? ANSWER For relief of ACUTE asthma attacks Is albuterol approved in children under 4? ANSWER Yes. How do beta-2 agonists affect calcium? ANSWER They open large conductions in calcium activated potassium channels = hyperpolarized airway smooth muscle cells 1. decreased intracellular calcium 2. increased potassium concentration 3. decreased myocleynase activity = smooth muscle relaxation and bronchodilation