ABCP Basic Sciences /Basic soil science Exam QUESTIONS CORRECTLY ANSWERED 2023

ABCP Basic Sciences /Basic soil science Exam QUESTIONS CORRECTLY ANSWERED 2023 Which of the following are examples of phase I metabolism? (Select 2) Oxidation Glucuronidation Hydrolysis Conjugation - ANSWER A, C Drugs that undergo zero order kinetics... Are eliminated at a constant percentage Are eliminated at a constant rate Are eliminated faster when more drug is present Rarely reach toxic levels - ANSWER B If a drug has a half life of 30 minutes, how long will it take for the drug to have a negligible therapeutic effect? 120-150 minutes 30 minutes 75 minutes 300 minutes - ANSWER A A drug that binds to the receptor without activating the receptor is an: Agonist Partial agonist Agonist-antagonist Antagonist - ANSWER D Which of the following are inhibitory neurotransmitters? (Select 2) GABA Glutamate Serotonin Glycine Acetylcholine - ANSWER A, D Which part of the local anesthetic structure determines the type/class of local anesthetic? Lipophilic aromatic ring Hydrophilic tail Intermediate chain There is only one class of local anesthetic - ANSWER C A local anesthetic exerts its action on which part of the body? Plasma membrane Inner portion of the Na channel Mitochondria Cytoplasm - ANSWER B The pKa of a local anesthetic helps to determine the___ Potency Duration of action Rate of uptake Onset of action - ANSWER D Which type of nerve fiber is affected by a local anesthetic first? C fiber A gamma fiber A alpha fiber A beta fiber B fiber - ANSWER E How is ropivacaine metabolized? Plasma cholinesterase Liver metabolism Renal excretion completely unchanged Acetylcholinesterase - ANSWER B A 90 kg patient is receiving an interscalene block and starts complaining of visual disturbances and begins twitching. What action should you immediately take? Transfer patient to cardiac OR for emergent cardiopulmonary bypass Administer 50 mcg of epinephrine Administer 135 mL of lipid emulsion Administer 50 mg propofol bolus - ANSWER C Which factors will cause a faster induction with inhalational agents? (Select 2) Low blood:gas solubility of agent Low FGF Hypoventilation Low cardiac output - ANSWER A, D A higher blood:gas coefficient relates to ___ A faster induction Lower potency A slower induction Mechanism of action - ANSWER C Which factors increase the MAC requirements? (Select 2) Male gender Acute cocaine usage BP 200/110 Elderly Hyperthermia Concurrent opioid administration - ANSWER B, E