AQA GCSE COMBINED SCIENCE: TRILOGY 8464/B/1H Biology Paper 1H Question Paper + Mark scheme [MERGED] June 2022 *jun228464b1h01* IB/M/Jun22/E14 8464/B/1H For Examiner’s Use Question Mark

AQA GCSE COMBINED SCIENCE: TRILOGY 8464/B/1H Biology Paper 1H Question Paper + Mark scheme [MERGED] June 2022 *junb1h01* IB/M/Jun22/E14 8464/B/1H For Examiner’s Use Question Mark 1 2 3 4 5 6 TOTAL Time allowed: 1 hour 15 minutes Materials For this paper you must have: • a ruler • a scientific calculator. Instructions • Use black ink or black ball-point pen. • Pencil should only be used for drawing. • Fill in the boxes at the top of this page. • Answer all questions in the spaces provided. • If you need extra space for your answer(s), use the lined pages at the end of this book. Write the question number against your answer(s). • Do all rough work in this book. Cross through any work you do not want to be marked. • In all calculations, show clearly how you work out your answer. Information • The maximum mark for this paper is 70. • The marks for questions are shown in brackets. • You are expected to use a calculator where appropriate. • You are reminded of the need for good English and clear presentation in your answers. Please write clearly in block capitals. Centre number Candidate number Surname Forename(s) Candidate signature I declare this is my own work. GCSE COMBINED SCIENCE: TRILOGY Higher Tier Biology Paper 1H H 2 *02* IB/M/Jun22/8464/B/1H There are no questions printed on this page DO NOT WRITE ON THIS PAGE ANSWER IN THE SPACES PROVIDED Do not write outside the box 3 *03* Turn over ► IB/M/Jun22/8464/B/1H Do not write outside the 0 1 Bacteria can cause a variety of diseases in humans. box 0 1 . 1 What are two similarities between a bacterial cell and an animal cell? [2 marks] Tick () two boxes. Both have a cell membrane. Both have a cell wall. Both have a nucleus. Both have cytoplasm. Both have plasmids. 0 1 . 2 Salmonella food poisoning is caused by bacteria in food. Give one symptom of salmonella food poisoning. Do not refer to vomiting or diarrhoea in your answer. [1 mark] Question 1 continues on the next page 4 *04* IB/M/Jun22/8464/B/1H Do not write outside the 0 1 box . 3 What is the name of the first antibiotic developed? [1 mark] A child with a severe bacterial infection was given a course of antibiotics. Figure 1 shows how the concentration of live bacteria in the child’s body changed when taking the course of antibiotics. Figure 1 5 *05* Turn over ► IB/M/Jun22/8464/B/1H Do not write outside the box 0 1 . 4 The concentration of live bacteria in the body continued to increase after starting the course of antibiotics. Suggest one reason why. [1 mark] 0 1 . 5 After 3 days of taking the antibiotic: • the child felt better • there were still bacteria in the child’s body. Why did the child feel better? [1 mark] Tick () one box. Bacteria had become immune to the antibiotic. The child had become resistant to the bacteria. There were fewer toxins in the body than at day 0 0 1 . 6 Suggest why doctors do not give antibiotics to patients with minor infections. [1 mark] Question 1 continues on the next page 6 *06* IB/M/Jun22/8464/B/1H Do not write outside the box 9 Figure 2 shows blood viewed using a microscope. Figure 2 0 1 . 7 A vaccine will stimulate the production of antibodies. Which part of the blood in Figure 2 produces antibodies? [1 mark] Tick () one box. A B C D 0 1 . 8 Which part of the blood in Figure 2 starts the clotting process? [1 mark] Tick () one box. A B C D 7 *07* Turn over ► IB/M/Jun22/8464/B/1H Do not write outside the 0 2 This question is about cell division. box 0 2 . 1 Write the biological structures from the box in the correct order of size. [1 mark] cell chromosome gene nucleus Smallest Largest Question 2 continues on the n