inhoudstafel ORGAANFYSIOLOGIE

I. Poelaert



ORGAANFYSIOLOGIE
17. Chapter 17: Blood
17.1. Functions of blood
 Transport
 Regulation
 Protection

17.2. Composition of blood
 Physical characteristics and volume
 Blood plasma
 Formed elements
17.3. Erythrocytes
 Structural characteristics
 Function of erythrocytes
 Production of erythrocytes
o Stages of erythropoiesis
 Regulation and requirements of erythropoiesis
o Hormonal control
o Dietary requirements for erythropoiesis
 Fate and destruction of erythrocytes
 Erythrocyte disorders
o Anemia
 Blood loss
 Not enough RBC being produced
 Iron-deficiency anemia
 Pernicious anemia
 Renal anemia
 Aplastic anemia
 Too many RBC destroyed
 Thalassemias
 Sickle-cell anemia
1

,I. Poelaert


o Polycythaemia
 Polycythaemia vera
 Secondary polycythaemia
17.4. Leukocytes
 General structure and functional charateristsics
o Granulocytes
 Neutrophils
 Eosinophils
 Basophils
o Agranulocytes
 Lymphocytes
 Monocytes
 Production and life span of leukocytes
o Leukopoiesis
o Granulocyte production
 Myelobasts
 Promyelocytes
 Myelocytes
 Band cells
 Mature granulocyte
o Agranulocyte production
 Monocytes
 lymphocytes
 Leukocytes disorders
o Leukemias
o Infectious mononucleosis
17.5. Platelets
17.6. Hemostasis
 Step 1: vascular spasm
 Step 2: platelet plug formation
 Step 3: coagulation
2

, I. Poelaert


 Step 4: Clot retraction and firbrinolysis
 Factors limiting clot growth and formation
o Factors limiting normal clot growth
o Factors preventing undesirable clotting
 Disorders of hemostasis
o Thromboembolic conditions
 Thrombi and emboli
 Anticoagulant drugs
o Bleeding disorders
 Thrombocytopenia
 Impaired liver function
 Hemophilia




3