NR 507 midterm Exam test

NR 507 midterm Exam test Hives (urticaria) are an example of a: Type 1 hypersensitivity reaction. Anaphylaxis is what type of reaction? type 1 hypersensitivity Which of the following are considered the "first responders" of the innate immune system? neutrophils Allergic contact dermatitis is an example of what type of hypersensitivity reaction. type 4 hypersensitivity reaction Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: IgG or IgM Type 1 hypersensitivity reaction is mediated by IgE Allergic asthma is an example of type 1 hypersensitivity reaction type 2 hypersensitivity tissue specific Primary effector cells of type 2 macrophages Examples of type 2 reactions drug allergies, hemolytic anemia, blood transfusion mismatch, allergies against infectious agents Type 2 causes The cell to be destroyed by the antibody Cell destruction through phagocytosis by macrophages Damage to the cell by neutrophils triggering phagocytosis Natural killer cells to release toxic substances that destroy the target cell Malfunction of the cell without destruction Type 3 hypersensitivity reaction antigen-antibody response Where does the antibody bind to the antigen in type 3 response? in blood or body fluids and then circulates to tissue Where does the antibody bind to the antigen in type 1, 2, and 4? on cell surface Primary effector cell in type 3 neutrophils example of type 3 reaction serum sickness type 4 hypersensitivity reaction cell-mediated response primary mediators of type 4 lymphocytes and macrophages type 4 mediated by T lymphocytes and do not use antibodies example of type 4 localized contact dermatitis (poison ivy)