Prepared by
Mrs. Lija Mathew
Assistant Professor
College of Physiotherapy
MTIMS
, Circulatory disturbances of obstructive nature:
Ischaemia
• Defined as deficient blood supply to part of a tissue.
• The cessation of blood supply may be complete (complete ischaemia) or partial (partial ischaemia
• Adverse effects of ischaemia may result from 3 ways:
1. Hypoxia due to deprivation of oxygen to tissues (common cause) & 4 types:
Hypoxic hypoxia : due to low oxygen in arterial blood.
ii) Anaemic hypoxia: due to low level of haemoglobin in blood.
iii) Stagnant hypoxia: due to inadequate blood supply.
iv) Histotoxic hypoxia: low oxygen uptake due to cellular toxicity.
2. Malnourishment of cells due to inadequate supply of nutrients to the tissue (i.e. glucose, amino ac
3. Inadequate clearance of metabolites which results in accumulation of metabolic waste-products
affected tissue. Eg: Following exercise ischemia results which produces muscle ache
Mrs. Lija Mathew
Assistant Professor
College of Physiotherapy
MTIMS
, Circulatory disturbances of obstructive nature:
Ischaemia
• Defined as deficient blood supply to part of a tissue.
• The cessation of blood supply may be complete (complete ischaemia) or partial (partial ischaemia
• Adverse effects of ischaemia may result from 3 ways:
1. Hypoxia due to deprivation of oxygen to tissues (common cause) & 4 types:
Hypoxic hypoxia : due to low oxygen in arterial blood.
ii) Anaemic hypoxia: due to low level of haemoglobin in blood.
iii) Stagnant hypoxia: due to inadequate blood supply.
iv) Histotoxic hypoxia: low oxygen uptake due to cellular toxicity.
2. Malnourishment of cells due to inadequate supply of nutrients to the tissue (i.e. glucose, amino ac
3. Inadequate clearance of metabolites which results in accumulation of metabolic waste-products
affected tissue. Eg: Following exercise ischemia results which produces muscle ache
