NURS C475/ NURSC475 Quiz 1 Answered_2021

NURS C475 Quiz 1 Answered How do genetic/genomic issues influence individual variation of the response to a specific drug? Select one: a. Genetic-based behavior problems that promote poor adherence to prescribed drug regimens b. Single gene disorders that reduce the function of the kidneys or the liver c. Age-related loss of alleles within the cells lining the intestinal tract d. Polymorphisms of genes encoding metabolizing enzymes Question 2 Question text Which condition provides the greatest support for a strong genetic contribution to autism spectrum disorders (ASDs)? Select one: a. People with some neurologic disorders also have features of ASDs. b. Concordance among dizygotic twins is 10%. c. Males are affected four times more frequently than females. d. ASDs are more likely to occur in children of parents who are over 35 at time of conception. Question 3 Question text A patient with a fractured elbow in the emergency department states that he needs morphine for pain rather than codeine because the last time he had a painful injury, codeine was not effective in managing his pain. What is the nurse’s best response or action? Select one: e. Communicate this information to the admitting physician. f. Reassure the patient that he will receive progressively higher dosages of codeine until his pain is controlled. g. Alert the health-care provider that this patient is “drug-seeking.” h. Ask the patient how much alcohol he ingests daily. Feedback The correct answer is: Communicate this information to the admitting physician. Question 4 Question text Which “schizophrenia fact” is correct? Select one: a. When one identical twin is affected with schizophrenia the other most certainly will be affected. b. Copy number variants appear to play the most important role in genetic risk for schizophrenia. c. When schizophrenia has more genetic influence, its onset begins in very early childhood. d. Because the phenotype of schizophrenia is so obvious, diagnosis and inheritance risk are the most easily determined of all the psychiatric disorders. Question 5 Question text What type of genetic test provides information about an asymptomatic person’s risk for having a child with a specific autosomal recessive disorder in the future? Select one: a. Carrier test b. Newborn screening c. Predictive test d. Diagnostic test Question 6 Question text What is the relationship among genes, DNA, and proteins? Select one: a. Proteins are the nitrogenous bases that form double strands of DNA in its helical shape. b. A gene is a section of DNA that provides the directions for synthesizing a specific protein. c. Protein is composed of DNA that is organized into specific gene sequences called amino acids. d. DNA is composed of a series of amino acids that provide the directions for synthesizing proteins. Question 7 Question text Why is determining the genetic contribution important to assess in stroke patients? Select one: a. Stroke classification and phenotype remain heterogeneous. b. Often the person with a stroke cannot provide accurate family information. c. Comorbidities mask the symptoms and delay the diagnosis. d. Environmental risk factors have equal contribution to the problem. Question 8 Question text Why are general physicians and surgeons NOT considered to be genetics professionals? Select one: a. The focus of their professional education is the study of medicine rather than genetics. b. Most of today’s physicians and surgeons were educated before completion of the human genome research project. c. These health-care professionals have minimal experience with genetics laboratory techniques. d. The typical patients seen by these health-care providers have acute conditions rather than chronic conditions, and thus genetic influence is irrelevant. Question 9 Question text Which statement best describes the role of tumor suppressor genes in cancer development? Select one: a. Tumor suppressor genes control or modify the activity of oncogenes, reducing the risk for cancer development. b. Tumor suppressor genes reduce/suppress immune function, increasing the risk for cancer development. c. Tumor suppressor genes are a type of oncogene that is only active in germ line cells and tissues. d. The presence of tumor suppressor genes increases the risk for gene damage by environmental carcinogens. Question 10 Why is pharmacogenetics/pharmacogenomics of particular interest in treating patients with psychiatric/mental health problems? Select one: e. Psychotropic medications have few side effects. f. Psychiatric medications may be effective in only a small group of patients. g. Genetics restricts patients to only one drug in each classification h. Most psychiatric illnesses are single gene disorders with predictable drug responses. Question 11 What is the heritability estimate for addiction to alcohol in both males and females? Select one: a. 10% to 20% b. 60% to 80% c. 50% to 60% d. 20% to 40% Question 12 Question text Which variable in a person with coronary artery disease increases the likelihood of a strong genetic influence in its expression? Select one: a. The problem is severe before age 50 years. b. The affected person has eaten a vegetarian diet for the past 5 years. c. The disorder is not present in the person’s dizygotic twin. d. The disorder is present in about 5% of the person’s maternal older male family members. Question 13 Question text Which lethal cardiac arrhythmia can occur as a complication of long QT syndrome? Select one: e. Mitral valve prolapse f. Prolonged atrial fibrillation g. Atrial node reentry tachycardia h. Torsade de Pointes Question 14 Question text What should be told to the patient who has been found to have a genetic mutation that increases the risk for colon cancer and says he does not want any of his family to know about this result? Select one: a. “It is not required that you tell anyone about this result; however, because your siblings and children may also be at risk for colon cancer, you should think about how this information might help them.” b. “It is not necessary to tell your siblings because they are adults, but you should tell your children so they can be tested before they decide to have children of their own.” c. “It is your decision to determine with whom, if anyone, you share this test result; however, if you do not tell any of your family members and they get colon cancer, you would be responsible for their developing the disease.” d. “It is required by law that you inform your siblings and your children about this result so that they also can be tested and monitored for colon cancer.” Question 15 Question text Which type of genetic testing is the most sensitive method for detecting any mutation in a specific gene? Select one: a. Fluorescence in situ hybridization b. Immunohistochemistry c. Direct DNA sequencing d. Banded chromosomal analysis