ATI Pharmacology Practice
Exam Questions And Correct
Answers (Verified Answers)
Plus Rationales 2026/2027
Q&A | Instant
1. A nurse is administering furosemide to a client with
hypertension. Which electrolyte imbalance is the client at greatest
risk for?
A. Hypokalemia
B. Hypernatremia
C. Hypercalcemia
D. Hypomagnesemia
Furosemide is a loop diuretic that increases the excretion of
potassium, sodium, and chloride. Hypokalemia is the most common
concern.
2. A client prescribed warfarin asks why regular blood tests are
needed. Which response is appropriate?
A. “It ensures your red blood cell count stays high.”
B. “It checks your platelet levels.”
C. “It measures your clotting ability to prevent bleeding or clots.”
D. “It monitors your kidney function.”
,Warfarin affects vitamin K-dependent clotting factors. Regular
PT/INR monitoring ensures therapeutic anticoagulation without
excessive bleeding.
3. A nurse is teaching a client about metformin. Which statement
indicates the client understands the teaching?
A. “I can drink alcohol freely while taking this medication.”
B. “I should take this medication with meals to reduce stomach
upset.”
C. “I should skip doses if I feel well.”
D. “I will need daily insulin injections while on this medication.”
Metformin can cause GI upset, which is minimized when taken with
food. Alcohol increases the risk of lactic acidosis.
4. Which adverse effect should the nurse monitor for in a client
taking lisinopril?
A. Hyperglycemia
B. Tachycardia
C. Persistent dry cough
D. Constipation
ACE inhibitors like lisinopril can cause a persistent, nonproductive
cough due to bradykinin accumulation.
5. A client taking digoxin has nausea, vomiting, and blurred vision.
What is the nurse’s priority action?
A. Administer the next dose as scheduled
B. Increase the dose of digoxin
C. Hold the medication and notify the provider
D. Encourage fluids
,These are classic signs of digoxin toxicity. The provider must be
notified and the dose may need adjustment.
6. A nurse is teaching a client about albuterol inhaler use. Which
statement indicates correct understanding?
A. “I will take this only at night.”
B. “I should use this medication as a rescue for sudden wheezing.”
C. “I should rinse my mouth after using this inhaler.”
D. “I must take this every 8 hours like a steroid.”
Albuterol is a short-acting beta-2 agonist used for acute
bronchospasm, not daily maintenance.
7. A client is prescribed sertraline. What should the nurse teach
about administration?
A. Take with grapefruit juice
B. Take in the morning to reduce insomnia
C. Take only when feeling anxious
D. Avoid reporting sexual side effects
SSRIs like sertraline may cause insomnia; taking in the morning
reduces this risk.
8. Which lab value should a nurse monitor for a client on heparin
therapy?
A. INR
B. aPTT
C. Creatinine
D. ALT
, Heparin enhances antithrombin III activity, prolonging aPTT. This
lab guides dosing to prevent bleeding or clotting.
9. A client is prescribed prednisone. Which instruction is important?
A. Stop immediately if feeling unwell
B. Take only when symptoms appear
C. Take with food to reduce gastric irritation
D. Avoid monitoring blood sugar
Prednisone is a corticosteroid that can irritate the stomach lining;
taking with food decreases this risk.
10. Which adverse effect is most concerning in a client taking
ciprofloxacin?
A. Diarrhea
B. Tendon rupture
C. Mild nausea
D. Headache
Fluoroquinolones like ciprofloxacin carry a risk of tendonitis and
tendon rupture, especially in older adults.
11. A nurse is teaching a client about levothyroxine. Which
statement shows understanding?
A. Take at night with food
B. Take in the morning on an empty stomach
C. Stop when feeling better
D. Take with iron supplements
Levothyroxine absorption decreases with food; best taken on an
empty stomach to optimize efficacy.
Exam Questions And Correct
Answers (Verified Answers)
Plus Rationales 2026/2027
Q&A | Instant
1. A nurse is administering furosemide to a client with
hypertension. Which electrolyte imbalance is the client at greatest
risk for?
A. Hypokalemia
B. Hypernatremia
C. Hypercalcemia
D. Hypomagnesemia
Furosemide is a loop diuretic that increases the excretion of
potassium, sodium, and chloride. Hypokalemia is the most common
concern.
2. A client prescribed warfarin asks why regular blood tests are
needed. Which response is appropriate?
A. “It ensures your red blood cell count stays high.”
B. “It checks your platelet levels.”
C. “It measures your clotting ability to prevent bleeding or clots.”
D. “It monitors your kidney function.”
,Warfarin affects vitamin K-dependent clotting factors. Regular
PT/INR monitoring ensures therapeutic anticoagulation without
excessive bleeding.
3. A nurse is teaching a client about metformin. Which statement
indicates the client understands the teaching?
A. “I can drink alcohol freely while taking this medication.”
B. “I should take this medication with meals to reduce stomach
upset.”
C. “I should skip doses if I feel well.”
D. “I will need daily insulin injections while on this medication.”
Metformin can cause GI upset, which is minimized when taken with
food. Alcohol increases the risk of lactic acidosis.
4. Which adverse effect should the nurse monitor for in a client
taking lisinopril?
A. Hyperglycemia
B. Tachycardia
C. Persistent dry cough
D. Constipation
ACE inhibitors like lisinopril can cause a persistent, nonproductive
cough due to bradykinin accumulation.
5. A client taking digoxin has nausea, vomiting, and blurred vision.
What is the nurse’s priority action?
A. Administer the next dose as scheduled
B. Increase the dose of digoxin
C. Hold the medication and notify the provider
D. Encourage fluids
,These are classic signs of digoxin toxicity. The provider must be
notified and the dose may need adjustment.
6. A nurse is teaching a client about albuterol inhaler use. Which
statement indicates correct understanding?
A. “I will take this only at night.”
B. “I should use this medication as a rescue for sudden wheezing.”
C. “I should rinse my mouth after using this inhaler.”
D. “I must take this every 8 hours like a steroid.”
Albuterol is a short-acting beta-2 agonist used for acute
bronchospasm, not daily maintenance.
7. A client is prescribed sertraline. What should the nurse teach
about administration?
A. Take with grapefruit juice
B. Take in the morning to reduce insomnia
C. Take only when feeling anxious
D. Avoid reporting sexual side effects
SSRIs like sertraline may cause insomnia; taking in the morning
reduces this risk.
8. Which lab value should a nurse monitor for a client on heparin
therapy?
A. INR
B. aPTT
C. Creatinine
D. ALT
, Heparin enhances antithrombin III activity, prolonging aPTT. This
lab guides dosing to prevent bleeding or clotting.
9. A client is prescribed prednisone. Which instruction is important?
A. Stop immediately if feeling unwell
B. Take only when symptoms appear
C. Take with food to reduce gastric irritation
D. Avoid monitoring blood sugar
Prednisone is a corticosteroid that can irritate the stomach lining;
taking with food decreases this risk.
10. Which adverse effect is most concerning in a client taking
ciprofloxacin?
A. Diarrhea
B. Tendon rupture
C. Mild nausea
D. Headache
Fluoroquinolones like ciprofloxacin carry a risk of tendonitis and
tendon rupture, especially in older adults.
11. A nurse is teaching a client about levothyroxine. Which
statement shows understanding?
A. Take at night with food
B. Take in the morning on an empty stomach
C. Stop when feeling better
D. Take with iron supplements
Levothyroxine absorption decreases with food; best taken on an
empty stomach to optimize efficacy.
