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HESI Exit RN Exam Practice Questions | 700+ NCLEX-Style Questions with Answers and Rationales for RN Review

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This HESI Exit RN Exam study resource includes over 700 high-quality NCLEX-style practice questions with detailed answers and rationales designed to support RN students preparing for HESI Exit exams. Covers core nursing concepts, critical thinking, clinical judgment, prioritization, and test-taking strategies. Created strictly for study and reference purposes, this material is ideal for nursing review, remediation, and exam readiness for the 2026–2027 academic cycle.

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HESI Exit RN Exam Practice Questions
| 700+ NCLEX-Style Questions with
Answers and Rationales for RN
Review


1. Following discharge teaching, a male client with duodenal ulcer tells the nurse the he will
drink plenty of dairy products, such as milk, to help coat and protect his ulcer. What is the
best follow-up action by the nurse?
Review with the client the need to avoid foods that are rich in milk and cream

2. A male client with hypertension, who received new antihypertensive prescriptions at his
last visit returns to the clinic two weeks later to evaluate his blood pressure (BP). His BP is
158/106 and he admits that he has not been taking the prescribed medication because the
drugs make him “feel bad”. In explaining the need for hypertension control, the nurse
should stress that an elevated BP places the client at risk for which pathophysiological
condition?
Stroke secondary to hemorrhage

3. The nurse observes an unlicensed assistive personnel (UAP) positioning a newly admitted
client who has a seizure disorder. The client is supine and the UAP is placing soft pillows
along the side rails. What action should the nurse implement?
Instruct the UAP to obtain soft blankets to secure to the side rails instead of
pillows.

4. An adolescent with major depressive disorder has been taking duloxetine (Cymbalta) for
the past 12 days. Which assessment finding requires immediate follow-up?
Describes life without purpose

, 5. A 60-year-old female client with a positive family history of ovarian cancer has developed
an abdominal mass and is being evaluated for possible ovarian cancer. Her Papanicolau
(Pap) smear results are negative. What information should the nurse include in the client’s
teaching plan?
Further evaluation involving surgery may be needed

6. A client who recently underwear a tracheostomy is being prepared for discharge to home.
Which instructions is most important for the nurse to include in the discharge plan?
Teach tracheal suctioning techniques
7. In assessing an adult client with a partial rebreather mask, the nurse notes that the oxygen
reservoir bag does not deflate completely during inspiration and the client’s respiratory
rate is 14 breaths / minute. What action should the nurse implement?
• Document the assessment data
• Rational: reservoir bag should not deflate completely during inspiration and the
client’s respiratory rate is within normal limits.
8. During shift report, the central electrocardiogram (EKG) monitoring system alarms.
Which client alarm should the nurse investigate firs?
• Respiratory apnea of 30 seconds
9. During a home visit, the nurse observed an elderly client with diabetes slip and fall. What
action should the nurse take first?
• Check the client for lacerations or fractures
10. At 0600 while admitting a woman for a schedule repeat cesarean section (C-Section), the
client tells the nurse that she drank a cup a coffee at 0400 because she wanted to avoid
getting a headache. Which action should the nurse take first?
• Inform the anesthesia care provider
11. After placing a stethoscope as seen in the picture, the nurse auscultates S1 and S2 heart
sounds. To determine if an S3 heart sound is present, what action should the nurse take
first?
• Listen with the bell at the same location
12. A 66-year-old woman is retiring and will no longer have a health insurance through her
place of employment. Which agency should the client be referred to by the employee
health nurse for health insurance needs?
• Medicare

13. A client who is taking an oral dose of a tetracycline complains of gastrointestinal upset.
What snack should the nurse instruct the client to take with the tetracycline?
• Toasted wheat bread and jelly

14. Following a lumbar puncture, a client voices several complaints. What complaint
indicated to the nurse that the client is experiencing a complication?
• “I have a headache that gets worse when I sit up”

• “I am having pain in my lower back when I move my legs”

• “My throat hurts when I swallow”

• “I feel sick to my stomach and am going to throw up”

, 15. An elderly client seems confused and reports the onset of nausea, dysuria, and urgency
with incontinence. Which action should the nurse implement?
• Obtain a clean catch mid-stream specimen

16. The nurse is assisting the mother of a child with phenylketonuria (PKU) to select foods
that are in keeping with the child’s dietary restrictions. Which foods are contraindicated
for this child?
• Foods sweetened with aspartame

17. Before preparing a client for the first surgical case of the day, a part-time scrub nurse asks
the circulating nurse if a 3 minute surgical hand scrub is adequate preparation for this
client. Which response should the circulating nurse provide?
• Direct the nurse to continue the surgical hand scrub for a 5 minute duration
18. Which breakfast selection indicates that the client understands the nurse’s instructions
about the dietary management of osteoporosis?

, Bagel with jelly and skim milk

19. The charge nurse of a critical care unit is informed at the beginning of the shift that
less than the optimal number of registered nurses will be working that shift. In
planning assignments, which client should receive the most care hours by a
registered nurse (RN)?
An 82-year-old client with Alzheimer’s disease newly-fractures femur who has a
Foley catheter and soft wrist restrains applied


20. A mother brings her 6-year-old child, who has just stepped on a rusty nail, to the
pediatrician’s office. Upon inspection, the nurse notes that the nail went through the
shoe and pierced the bottom of the child’s foot. Which action should the nurse
implement first?
• Cleanse the foot with soap and water and apply an antibiotic ointment
Provide teaching about the need for a tetanus booster within the next 72 hours.
• have the mother check the child's temperature q4h for the next 24 hours
• transfer the child to the emergency department to receive a gamma globulin
injection
21. The mother of an adolescent tells the clinic nurse, “My son has athlete’s foot, I have
been applying triple antibiotic ointment for two days, but there has been no
improvement.” What instruction should the nurse provide?
Stop using the ointment and encourage complete drying of the feet and wearing
clean socks.
22. A 26-year-old female client is admitted to the hospital for treatment of a simple
goiter, and levothyroxine sodium (Synthroid) is prescribed. Which symptoms
indicate to the nurse that the prescribed dosage is too high for this client? The client
experiences
• Bradycardia and constipation

Lethargy and lack of appetite • Muscle cramping and dry, flushed skin
• Palpitations and shortness of breath
23. A client with a history of heart failure presents to the clinic with a nausea, vomiting,
yellow vision and palpitations. Which finding is most important for the nurse to
assess to the client?
Obtain a list of medications taken for cardiac history
24. The healthcare provider prescribes an IV solution of isoproterenol (Isuprel) 1 mg in
250 ml of D5W at 300 mcg/hour. The nurse should program the infusion pump to
deliver how many ml/hour? (Enter numeric value only.)
• 75
• Rationale: Convert mg to mcg and use the formula D/H x Q. 300 mcg/hour /
1,000 mcg x 250 ml = 3/1 x 25 = 75 ml/hour

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