6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
Performance
Exit
EAQ Chapter 3, Pharmacokinetics and
Pharmacodynamics - Proficient Level
Due Jun 8, 2025 by 11:59 pm
Passed
56 out of 60 questions answered correctly
Completed on Jun 3, 2025 9:01 pm
Incorrect (4)
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Which effect would be attributed to the combination of a
diuretic and a beta blocker when caring for a patient being
treated for hypertension?
Additive drug effect
Increase in side effects
Synergistic drug effect
Antagonistic drug effect
Rationale
When two drugs with similar actions are administered, the drug
interaction has an additive effect. An additive effect is the sum of the
effects of the two drugs. When a diuretic and a beta blocker are
administered for the treatment of hypertension, there is a more
pronounced blood pressure–lowering effect. This drug combination does
not cause an increase in side effects. In some cases, when two or more
drugs are given together, one drug can potentiate, or have a synergistic
effect on, the other. For example, a synergistic effect is observed when
promethazine is used with meperidine in patients postsurgery.
Promethazine enhances the drowsiness effect of meperidine. An
antagonistic drug effect occurs when two drugs with opposite reactions
are administered together and each drug cancels the effect of the other.
For example, when isoproterenol is used in an emergency to treat
bradycardia in a patient receiving a drug that decreases blood pressure and
heart rate, the action of each drug is canceled. The combination of a
diuretic and a beta blocker does not have synergistic or antagonistic
effects.
p. 29
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,6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
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The nurse administers a drug that has a half-life of 6 hours. If
the dose of the drug is 200 mg/L, what would be the
concentration of the drug after 12 hours? Record your answer
using a whole number. 100 50 mg/L
Rationale
Half-life means the time taken by the body to eliminate 50% of the drug.
So after 6 hours, the concentration of the drug would be 100 mg/L, and
after 12 hours, it would be 50 mg/L.
p. 23
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The nurse is preparing to infuse the 0900 dose of gentamycin
80 mg intravenously (IV) over 1 hour to a patient for an
infection. At which time would the nurse obtain an ordered
blood sample to determine the peak drug level?
0800
0900
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, 6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
1000
1100
Rationale
The peak drug level indicates the rate of drug absorption and is obtained
30 to 60 minutes after the dose is complete. The nurse initiates the
infusion at 0900, and it infuses for 1 hour. Therefore the nurse would
obtain the peak drug level 30 to 60 minutes after the infusion finishes,
which would be 1100. A trough level would be obtained between 0800 and
0900. The infusion would be complete at 1000.
p. 6
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The nurse is providing drug education to a patient with a new
prescription for oral ciprofloxacin. Which action taken by the
patient indicates a need for further education?
Drinks glass of milk with dose
Takes medication on an empty stomach
Takes antacid 2 hours before medication
Holds oral iron dose for 2 hours after ciprofloxacin
Rationale
Dairy products should be avoided 1 hour before and 2 hours after taking
ciprofloxacin, as dairy products can interfere with absorption. Therefore
https://eaqng.elsevier.com/#/quizPerformance/83628513 4/56
Performance
Exit
EAQ Chapter 3, Pharmacokinetics and
Pharmacodynamics - Proficient Level
Due Jun 8, 2025 by 11:59 pm
Passed
56 out of 60 questions answered correctly
Completed on Jun 3, 2025 9:01 pm
Incorrect (4)
Report content error
https://eaqng.elsevier.com/#/quizPerformance/83628513 1/56
,6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
Which effect would be attributed to the combination of a
diuretic and a beta blocker when caring for a patient being
treated for hypertension?
Additive drug effect
Increase in side effects
Synergistic drug effect
Antagonistic drug effect
Rationale
When two drugs with similar actions are administered, the drug
interaction has an additive effect. An additive effect is the sum of the
effects of the two drugs. When a diuretic and a beta blocker are
administered for the treatment of hypertension, there is a more
pronounced blood pressure–lowering effect. This drug combination does
not cause an increase in side effects. In some cases, when two or more
drugs are given together, one drug can potentiate, or have a synergistic
effect on, the other. For example, a synergistic effect is observed when
promethazine is used with meperidine in patients postsurgery.
Promethazine enhances the drowsiness effect of meperidine. An
antagonistic drug effect occurs when two drugs with opposite reactions
are administered together and each drug cancels the effect of the other.
For example, when isoproterenol is used in an emergency to treat
bradycardia in a patient receiving a drug that decreases blood pressure and
heart rate, the action of each drug is canceled. The combination of a
diuretic and a beta blocker does not have synergistic or antagonistic
effects.
p. 29
https://eaqng.elsevier.com/#/quizPerformance/83628513 2/56
,6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
Report content error
The nurse administers a drug that has a half-life of 6 hours. If
the dose of the drug is 200 mg/L, what would be the
concentration of the drug after 12 hours? Record your answer
using a whole number. 100 50 mg/L
Rationale
Half-life means the time taken by the body to eliminate 50% of the drug.
So after 6 hours, the concentration of the drug would be 100 mg/L, and
after 12 hours, it would be 50 mg/L.
p. 23
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The nurse is preparing to infuse the 0900 dose of gentamycin
80 mg intravenously (IV) over 1 hour to a patient for an
infection. At which time would the nurse obtain an ordered
blood sample to determine the peak drug level?
0800
0900
https://eaqng.elsevier.com/#/quizPerformance/83628513 3/56
, 6/4/25, 8:24 PM Elsevier Adaptive Quizzing - Quiz performance
1000
1100
Rationale
The peak drug level indicates the rate of drug absorption and is obtained
30 to 60 minutes after the dose is complete. The nurse initiates the
infusion at 0900, and it infuses for 1 hour. Therefore the nurse would
obtain the peak drug level 30 to 60 minutes after the infusion finishes,
which would be 1100. A trough level would be obtained between 0800 and
0900. The infusion would be complete at 1000.
p. 6
Report content error
The nurse is providing drug education to a patient with a new
prescription for oral ciprofloxacin. Which action taken by the
patient indicates a need for further education?
Drinks glass of milk with dose
Takes medication on an empty stomach
Takes antacid 2 hours before medication
Holds oral iron dose for 2 hours after ciprofloxacin
Rationale
Dairy products should be avoided 1 hour before and 2 hours after taking
ciprofloxacin, as dairy products can interfere with absorption. Therefore
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