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Immunology Exam MCQs
Immune System
28. An example of Innate Immunity is:
a) Antibody Production by Plasma Cells
b) Antigen removal by Cilia in the Respiratory Tract
c) Complement activation by antibody bound to surface of a bacterium
d) Memory response to Influenzae Virus
e) Recognition and Killing of Virus infected cells by Cytotoxic T. Cells
29. Humoral Immunity can be acquired passively by:
a) Catching a Virus from a friend by shaking hands
b) Receiving a Vaccine of Influenzae Virus
c) Receiving Serum from someone who has recovered from an infection
d) Receiving Leukocytes from an Immune Family Member
e) Sharing of Soda with someone who has a Cold
30. An advantage of Passive Immunity over Active Immunity is:
a) It stays for a short time
b) It stays for a long time
c) Immediate availability of Immunity
d) Onset of Immunity is Slow
e) It has no risks for developing Hypersensitivity
31. Which of the following is a Primary Lymphoid Tissue:
a) Spleen
b) Mucosa-Associated Lymphoid Tissue
c) Bone Marrow
d) Lymph Nodes
e) Tonsils
32. An Immune Response takes place in the:
a) Bone Marrow
b) Lymph Nodes
c) Thymus
d) Liver
e) Skin
33. Peripheral Lymphoid Organs:
a) Are centrally located in the abdomen to protect their vital functions
b) Are designed to maximize contact between antigen and lymphocytes
c) Produce antigen specific lymphocytes from stem cells in response to
antigen
d) Hides the antigen to minimize its damage to the body
e) Store large numbers of activated cells for rapid response to antigen
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34. Surface or membrane markers on Immune System cells:
a) Are present on lymphocytes but not other cells of immune system
b) Are put there by immunologists so they can identify functional cell types
c) Attract antigen to the secondary lymphoid organs
d) Can be antigen receptors
e) Develop once the cells leave the primary lymphoid organs
35. Surface markers of B-Lymphocytes include:
a) TCR
b) CD4
c) IgM
d) CD8
e) CD3
36. Surface markers of macrophages include:
a) IgM
b) CD3
c) C3b
d) CD4
e) BCR
37. Which of the following is an Antigen Presenting Cell:
a) T-Helper Lymphocyte
b) Plasma Cell
c) Macrophage
d) T-Cytotoxic Lymphocytes
e) Mast Cells
38. Hematopoetic Stem Cells are pluripotent, which means that they:
a) Are antigen specific cells
b) Are capable of developing into any blood cell
c) Are committed to produce cells of a single lineage
d) Are not self-reneweing
e) Will develop into T and B lymphocyte of many different antigen
specificities
39. The following are Phagocytic Cells except:
a) Macrophages
b) Monocytes
c) Neutrophils
d) Mast Cells
e) Basophils
40. Phagocytosis:
a) Can be stimulated by antigen binding to complement or antibody
b) Is an antigen-specific process
c) Must be preceded by antigen processing or digestion
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d) Rids the body of virus-infected cells
e) Only occurs after plasma cells begin secreting antibodys
41. Primary Lymphoid Organs:
a) Are efficient in exposing T cells to foreign antigen presented on dendritic
cells
b) Are the primary site of antibody synthesis and release
c) Filter blood and trap blood borne antigens
d) Provide the microenvironment for maturation of T and B cells
e) Line the mucosal surfaces of the body for efficient antigen contact
42. Complement:
a) Is a group of active proteolytic enzymes found in serum
b) Is secreted by macrophages and hepatocytes in response to antigen binding
c) Participates in both innate and adaptive immune response
d) Prevent lysis or virus-infected cells
e) All of the above
43. The Classical Complement Cascade:
a) Is completely independent of the alternative complement cascade
b) Is initiated by IgM only after its FAB regions bind to Antigen
c) Must begin before the alternative pathway to provide the initial C3b
d) Requires at least two IgM molecules for activation
e) Occurs only after C12 binds Fab regions of two IgG molecules
44. Formation of MAC Complex on the surface of the antigen:
a) Attracts leukocytes to the antigen
b) Is required for inflammation
c) Is the final step in complement-mediated osponization
d) Kills pathogens by releasing their lytic granules
e) Results from both the Classical and Alternative Pathways
45. Innate Immune Responses are like adaptive immunity in that they:
a) Are antigen specific
b) Demonstrate immune memory
c) Involves macrophages and complements
d) Involves T and B lymphocytes
e) Use immunoglobulin IgG and IgM
46. Phagocytes kill bacteria intracellularly by using the following except:
a) H2O2
b) Hydrolytic Enzymes
c) Low pH
d) Lysozymes
e) Cytotoxins
47. Immunoglobulins are synthesized by:
a) Activated T Lymphocytes
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Immunology Exam MCQs
Immune System
28. An example of Innate Immunity is:
a) Antibody Production by Plasma Cells
b) Antigen removal by Cilia in the Respiratory Tract
c) Complement activation by antibody bound to surface of a bacterium
d) Memory response to Influenzae Virus
e) Recognition and Killing of Virus infected cells by Cytotoxic T. Cells
29. Humoral Immunity can be acquired passively by:
a) Catching a Virus from a friend by shaking hands
b) Receiving a Vaccine of Influenzae Virus
c) Receiving Serum from someone who has recovered from an infection
d) Receiving Leukocytes from an Immune Family Member
e) Sharing of Soda with someone who has a Cold
30. An advantage of Passive Immunity over Active Immunity is:
a) It stays for a short time
b) It stays for a long time
c) Immediate availability of Immunity
d) Onset of Immunity is Slow
e) It has no risks for developing Hypersensitivity
31. Which of the following is a Primary Lymphoid Tissue:
a) Spleen
b) Mucosa-Associated Lymphoid Tissue
c) Bone Marrow
d) Lymph Nodes
e) Tonsils
32. An Immune Response takes place in the:
a) Bone Marrow
b) Lymph Nodes
c) Thymus
d) Liver
e) Skin
33. Peripheral Lymphoid Organs:
a) Are centrally located in the abdomen to protect their vital functions
b) Are designed to maximize contact between antigen and lymphocytes
c) Produce antigen specific lymphocytes from stem cells in response to
antigen
d) Hides the antigen to minimize its damage to the body
e) Store large numbers of activated cells for rapid response to antigen
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34. Surface or membrane markers on Immune System cells:
a) Are present on lymphocytes but not other cells of immune system
b) Are put there by immunologists so they can identify functional cell types
c) Attract antigen to the secondary lymphoid organs
d) Can be antigen receptors
e) Develop once the cells leave the primary lymphoid organs
35. Surface markers of B-Lymphocytes include:
a) TCR
b) CD4
c) IgM
d) CD8
e) CD3
36. Surface markers of macrophages include:
a) IgM
b) CD3
c) C3b
d) CD4
e) BCR
37. Which of the following is an Antigen Presenting Cell:
a) T-Helper Lymphocyte
b) Plasma Cell
c) Macrophage
d) T-Cytotoxic Lymphocytes
e) Mast Cells
38. Hematopoetic Stem Cells are pluripotent, which means that they:
a) Are antigen specific cells
b) Are capable of developing into any blood cell
c) Are committed to produce cells of a single lineage
d) Are not self-reneweing
e) Will develop into T and B lymphocyte of many different antigen
specificities
39. The following are Phagocytic Cells except:
a) Macrophages
b) Monocytes
c) Neutrophils
d) Mast Cells
e) Basophils
40. Phagocytosis:
a) Can be stimulated by antigen binding to complement or antibody
b) Is an antigen-specific process
c) Must be preceded by antigen processing or digestion
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d) Rids the body of virus-infected cells
e) Only occurs after plasma cells begin secreting antibodys
41. Primary Lymphoid Organs:
a) Are efficient in exposing T cells to foreign antigen presented on dendritic
cells
b) Are the primary site of antibody synthesis and release
c) Filter blood and trap blood borne antigens
d) Provide the microenvironment for maturation of T and B cells
e) Line the mucosal surfaces of the body for efficient antigen contact
42. Complement:
a) Is a group of active proteolytic enzymes found in serum
b) Is secreted by macrophages and hepatocytes in response to antigen binding
c) Participates in both innate and adaptive immune response
d) Prevent lysis or virus-infected cells
e) All of the above
43. The Classical Complement Cascade:
a) Is completely independent of the alternative complement cascade
b) Is initiated by IgM only after its FAB regions bind to Antigen
c) Must begin before the alternative pathway to provide the initial C3b
d) Requires at least two IgM molecules for activation
e) Occurs only after C12 binds Fab regions of two IgG molecules
44. Formation of MAC Complex on the surface of the antigen:
a) Attracts leukocytes to the antigen
b) Is required for inflammation
c) Is the final step in complement-mediated osponization
d) Kills pathogens by releasing their lytic granules
e) Results from both the Classical and Alternative Pathways
45. Innate Immune Responses are like adaptive immunity in that they:
a) Are antigen specific
b) Demonstrate immune memory
c) Involves macrophages and complements
d) Involves T and B lymphocytes
e) Use immunoglobulin IgG and IgM
46. Phagocytes kill bacteria intracellularly by using the following except:
a) H2O2
b) Hydrolytic Enzymes
c) Low pH
d) Lysozymes
e) Cytotoxins
47. Immunoglobulins are synthesized by:
a) Activated T Lymphocytes
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