Kidney General
Kidney functions
Regulation of wat er and Electrolyte balance s
Regulation of arterialpressvre
-
* for maintal nance of home ostasis excretion of Nat und weiter
* long -
term regulation by
* renal adaption to dietintake
short term regulation by hormonell vasoactivators
-
* -
secrets on of
Regulation of acid -
base balance
high Nat intake
* excretion of acids
f
accu mutation of Nat * regulation Of body fluid buffer stores
t
increased
extracellular fluid volume Regulation of erythrocyte production
/
L \ * secret on of erythropoetin
↳ stimulated by hypoxia
hormonell changes compensatory signals
↳ decreasedsecretion leadstoanemia
\ ✓ di hydroxy vitamin D ] ( coilcitriol )
increased Nat excretion Regulation of 1,25 -
production
* hydroxyl ation Of the Vitamin at position 1
* essential for normal ( a " deposition in bone and re absorption by at tract
* regulation of calcium und phosphate
Glucose synthesis ( Gluconeogenese's )
* during pro long ed fasting
Renal bloodsupply
PO , =
blood flow to Kidneys E 22% Of cardiac 1100mi / min 80mm Hg
Output =
)
unique in haring two capilla rybeds
}
↳ glomerular capillaries arranged in series
separate d by efferentarterioles
↳ peri tubular capilla ries
efferentarterioles :
regvlatehydrostaticpressvre in glomerular capillaries
-÷: ÷: : : : %:c:*:::-.
adjvsted resistance of afferent and afferent arterien les regvlates . . .
. . .
hydrostatic pressure
. . .
glomervlar filtration rate
. . . tubular reabsorption
✓
nephron =
functional unit
POZ =
↳ urine production ① mmHg
↳ 800.000 -
1.000.000 In euch kidney
↳ can it be regeneratedbykidneys
↳ numberdecreases with age and diseases
↳ adaptive changes in healthynephronscompensate diseases
Kidney functions
Regulation of wat er and Electrolyte balance s
Regulation of arterialpressvre
-
* for maintal nance of home ostasis excretion of Nat und weiter
* long -
term regulation by
* renal adaption to dietintake
short term regulation by hormonell vasoactivators
-
* -
secrets on of
Regulation of acid -
base balance
high Nat intake
* excretion of acids
f
accu mutation of Nat * regulation Of body fluid buffer stores
t
increased
extracellular fluid volume Regulation of erythrocyte production
/
L \ * secret on of erythropoetin
↳ stimulated by hypoxia
hormonell changes compensatory signals
↳ decreasedsecretion leadstoanemia
\ ✓ di hydroxy vitamin D ] ( coilcitriol )
increased Nat excretion Regulation of 1,25 -
production
* hydroxyl ation Of the Vitamin at position 1
* essential for normal ( a " deposition in bone and re absorption by at tract
* regulation of calcium und phosphate
Glucose synthesis ( Gluconeogenese's )
* during pro long ed fasting
Renal bloodsupply
PO , =
blood flow to Kidneys E 22% Of cardiac 1100mi / min 80mm Hg
Output =
)
unique in haring two capilla rybeds
}
↳ glomerular capillaries arranged in series
separate d by efferentarterioles
↳ peri tubular capilla ries
efferentarterioles :
regvlatehydrostaticpressvre in glomerular capillaries
-÷: ÷: : : : %:c:*:::-.
adjvsted resistance of afferent and afferent arterien les regvlates . . .
. . .
hydrostatic pressure
. . .
glomervlar filtration rate
. . . tubular reabsorption
✓
nephron =
functional unit
POZ =
↳ urine production ① mmHg
↳ 800.000 -
1.000.000 In euch kidney
↳ can it be regeneratedbykidneys
↳ numberdecreases with age and diseases
↳ adaptive changes in healthynephronscompensate diseases
