Clayton's Basic Pharmacology for Nurses 19th Edition Unit 3: Drugs
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
1. A-male-patient-is-being-treated-for-benign-prostatic-hyperplasia-and-has-
stopped-taking-his-alpha-adrenergic-antagonist-medication-
because-of-ejaculatory-difficulties.-Which-medication-does-the-nurse-expect-the-
provider-to-prescribe?
a. Alfuzosin-[Uroxatral]
b. Prazosin-[Minipress]
c. Silodosin-[Rapaflo]
d. Tamsulosin-[Flomax]---CORRECT-ANSWER-a.-Alfuzosin-[Uroxatral]
2. A-nurse-is-administering-an-agonist-drug-that-acts-on-postganglionic-neurons-
of-the-sympathetic-nervous-system.-Which-response-will-the-nurse-expect-to-
see?
a. Decreased-sweating
b. Bronchodilation
c. Increased-cardiac-output
d. Pinpoint-pupils---CORRECT-ANSWER-c.-Increased-cardiac-output
3. A-nurse-is-administering-drug-X-to-a-patient.-The-drug-information-states-that-
the-drug-acts-by-activating-receptors-in-the-peripheral-
4. nervous-system-by-increasing-transmitter-synthesis.-The-nurse-understands-
that-the-effect-of-this-drug-is-to:
a. activate-axonal-conduction.
b. enhance-transmitter-storage.
c. increase-receptor-activation.
d. synthesize-supertransmitters.---CORRECT-ANSWER-c.-increase-
receptor-activation.
5. A-nurse-is-caring-for-a-newborn-1-day-after-delivery.-The-infant's-mother-used-
betaxolol-during-pregnancy.-The-nurse-will-expect-to-monitor-this-infant-for-
which-condition?
a. Hyperglycemia
b. Hyperthyroidism
c. Respiratory-distress
d. Tachycardia---CORRECT-ANSWER-c.-Respiratory-distress
6. A-nurse-is-caring-for-a-patient-who-has-myasthenia-gravis.-The-prescriber-has-
ordered-neostigmine-[Prostigmin].-An-important-initial-nursing-action-before-
administration-of-the-medication-includes-assessing:
a. the-ability-to-raise-the-eyelids.
b. level-of-fatigue.
, Clayton's Basic Pharmacology for Nurses 19th Edition Unit 3: Drugs
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
c. skeletal-muscle-strength.
d. swallowing-ability---CORRECT-ANSWER-d.-swallowing-ability
7. A-nurse-is-caring-for-an-intubated-patient-who-is-receiving-pancuronium-for-
neuromuscular-blockade.-The-patient's-eyes-are-closed,-and-the-patient-is-not-
moving-any-extremities.-The-heart-rate-is-76-beats/min,-and-the-blood-
pressure-is-110/70-mm-Hg.-The-nurse-caring-for-this-patient-will-do-what?
a. Request-an-order-for-an-antihistamine-to-prevent-a-further-drop-in-
blood-pressure.
b. Request-an-order-for-serum-electrolytes-to-evaluate-for-hyperkalemia.
c. Review-the-patient's-chart-for-a-history-of-myasthenia-gravis-(MG).
d. Talk-to-the-patient-while-giving-care-and-explain-all-procedures.---
CORRECT-ANSWER-d.-Talk-to-the-patient-while-giving-care-and-
explain-all-procedures.
8. A-nurse-is-discussing-phentolamine-[OraVerse]-with-a-nursing-student.-Which-
statement-by-the-student-indicates-the-need-for-further-teaching?
a. "Phentolamine-can-be-used-to-block-both-epinephrine--and-
norepinephrine-mediated-vasoconstriction."
b.-"Phentolamine-can-be-used-to-prevent-tissue-necrosis-after-extravasation-of---
--drugs-such-as-norepinephrine."
c.-"Phentolamine-is-a-competitive-adrenergic-agonist-that-acts-selectively-on-
alpha1-receptors."
d.-"Side-effects-of-phentolamine-may-include-tachycardia-and-hypotension."---
CORRECT-ANSWER-c.-"Phentolamine-is-a-competitive-adrenergic-agonist-
that-acts-selectively-on-alpha1-receptors."
9. A-nurse-is-explaining-activation-of-beta2-receptors-to-nursing-students-during-
a-clinical-rotation-at-the-hospital.-Which-statement-by-a-student-demonstrates-
a-need-for-further-teaching?
a. "Beta2-activation-results-in-bronchodilation."
b. "Beta2-activation-results-in-contraction-of-uterine-muscle."
c. "Beta2-activation-results-in-glycogenolysis."
d. "Beta2-activation-results-in-vasodilation-of-skeletal-muscles."---
CORRECT-ANSWER-b.-"Beta2-activation-results-in-contraction-of-
uterine-muscle."
10. A-nurse-is-helping-a-nursing-student-who-is-administering-a-medication-to-a-
patient-with-myasthenia-gravis.-Which-statement-by-the-
student-indicates-the-need-for-further-teaching?
, Clayton's Basic Pharmacology for Nurses 19th Edition Unit 3: Drugs
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
a. "I-will-ask-the-patient-to-sip-some-water-before-giving-the-medication."
b. "I-will-let-the-patient-sleep-after-giving-the-medication,-because-rest-is-
important."
c. "I-will-record-muscle-strength-assessments-before-and-after-I-give-the-
medication."
d.-"I-will-report-excessive-salivation-to-the-patient's-prescriber."---CORRECT-
ANSWER-b.-"I-will-let-the-patient-sleep-after-giving-the-medication,-because-
rest-is-important."
11. A-nurse-is-preparing-to-administer-a-medication-and-learns-that-it-is-a-
nonselective-agonist-drug.-What-does-the-nurse-understand-about-this-drug?
a. It-directly-activates-receptors-to-affect-many-physiologic-processes.
b. It-directly-activates-receptors-to-affect-a-specific-physiologic-process.
c. It-prevents-receptor-activation-to-affect-many-physiologic-processes.
d. It-prevents-receptor-activation-to-affect-a-specific-physiologic-processes.--
-CORRECT-ANSWER-a.-It-directly-activates-receptors-to-affect-many-
physiologic-processes.
12. A-nurse-is-reviewing-nursing-actions-for-emergency-treatment-of-malignant-
hyperthermia-with-a-group-of-nursing-students.-Which-statement-by-a-student-
indicates-a-need-for-further-teaching?
a. "Analgesics-should-be-given-to-help-with-muscle-pain."
b. "Dantrolene-helps-to-slow-the-metabolic-activity-in-skeletal-muscles."
c. "If-malignant-hyperthermia-occurs,-the-succinylcholine-must-be-stopped-
immediately."
d.-"The-patient-may-need-an-intravenous-infusion-of-cold-saline."---CORRECT-
ANSWER-a.-"Analgesics-should-be-given-to-help-with-muscle-pain."
13. A-nurse-is-teaching-a-group-of-nursing-students-about-irreversible-
cholinesterase-inhibitors.-Which-statement-by-a-student-indicates-
understanding-of-theteaching?
a. "Diazepam-is-given-to-reverse-inhibition-of-cholinesterase-when-
overdose-
occurs."
b.-"Irreversible-cholinesterase-inhibitors-are-rapidly-absorbed-by-all-routes."
c.-"These-agents-are-often-used-to-treat-glaucoma."
d.-"Toxic-doses-of-these-agents-produce-an-anticholinergic-crisis."---CORRECT-
ANSWER-b.-"Irreversible-cholinesterase-inhibitors-are-rapidly-absorbed-by-all-
routes."
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
1. A-male-patient-is-being-treated-for-benign-prostatic-hyperplasia-and-has-
stopped-taking-his-alpha-adrenergic-antagonist-medication-
because-of-ejaculatory-difficulties.-Which-medication-does-the-nurse-expect-the-
provider-to-prescribe?
a. Alfuzosin-[Uroxatral]
b. Prazosin-[Minipress]
c. Silodosin-[Rapaflo]
d. Tamsulosin-[Flomax]---CORRECT-ANSWER-a.-Alfuzosin-[Uroxatral]
2. A-nurse-is-administering-an-agonist-drug-that-acts-on-postganglionic-neurons-
of-the-sympathetic-nervous-system.-Which-response-will-the-nurse-expect-to-
see?
a. Decreased-sweating
b. Bronchodilation
c. Increased-cardiac-output
d. Pinpoint-pupils---CORRECT-ANSWER-c.-Increased-cardiac-output
3. A-nurse-is-administering-drug-X-to-a-patient.-The-drug-information-states-that-
the-drug-acts-by-activating-receptors-in-the-peripheral-
4. nervous-system-by-increasing-transmitter-synthesis.-The-nurse-understands-
that-the-effect-of-this-drug-is-to:
a. activate-axonal-conduction.
b. enhance-transmitter-storage.
c. increase-receptor-activation.
d. synthesize-supertransmitters.---CORRECT-ANSWER-c.-increase-
receptor-activation.
5. A-nurse-is-caring-for-a-newborn-1-day-after-delivery.-The-infant's-mother-used-
betaxolol-during-pregnancy.-The-nurse-will-expect-to-monitor-this-infant-for-
which-condition?
a. Hyperglycemia
b. Hyperthyroidism
c. Respiratory-distress
d. Tachycardia---CORRECT-ANSWER-c.-Respiratory-distress
6. A-nurse-is-caring-for-a-patient-who-has-myasthenia-gravis.-The-prescriber-has-
ordered-neostigmine-[Prostigmin].-An-important-initial-nursing-action-before-
administration-of-the-medication-includes-assessing:
a. the-ability-to-raise-the-eyelids.
b. level-of-fatigue.
, Clayton's Basic Pharmacology for Nurses 19th Edition Unit 3: Drugs
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
c. skeletal-muscle-strength.
d. swallowing-ability---CORRECT-ANSWER-d.-swallowing-ability
7. A-nurse-is-caring-for-an-intubated-patient-who-is-receiving-pancuronium-for-
neuromuscular-blockade.-The-patient's-eyes-are-closed,-and-the-patient-is-not-
moving-any-extremities.-The-heart-rate-is-76-beats/min,-and-the-blood-
pressure-is-110/70-mm-Hg.-The-nurse-caring-for-this-patient-will-do-what?
a. Request-an-order-for-an-antihistamine-to-prevent-a-further-drop-in-
blood-pressure.
b. Request-an-order-for-serum-electrolytes-to-evaluate-for-hyperkalemia.
c. Review-the-patient's-chart-for-a-history-of-myasthenia-gravis-(MG).
d. Talk-to-the-patient-while-giving-care-and-explain-all-procedures.---
CORRECT-ANSWER-d.-Talk-to-the-patient-while-giving-care-and-
explain-all-procedures.
8. A-nurse-is-discussing-phentolamine-[OraVerse]-with-a-nursing-student.-Which-
statement-by-the-student-indicates-the-need-for-further-teaching?
a. "Phentolamine-can-be-used-to-block-both-epinephrine--and-
norepinephrine-mediated-vasoconstriction."
b.-"Phentolamine-can-be-used-to-prevent-tissue-necrosis-after-extravasation-of---
--drugs-such-as-norepinephrine."
c.-"Phentolamine-is-a-competitive-adrenergic-agonist-that-acts-selectively-on-
alpha1-receptors."
d.-"Side-effects-of-phentolamine-may-include-tachycardia-and-hypotension."---
CORRECT-ANSWER-c.-"Phentolamine-is-a-competitive-adrenergic-agonist-
that-acts-selectively-on-alpha1-receptors."
9. A-nurse-is-explaining-activation-of-beta2-receptors-to-nursing-students-during-
a-clinical-rotation-at-the-hospital.-Which-statement-by-a-student-demonstrates-
a-need-for-further-teaching?
a. "Beta2-activation-results-in-bronchodilation."
b. "Beta2-activation-results-in-contraction-of-uterine-muscle."
c. "Beta2-activation-results-in-glycogenolysis."
d. "Beta2-activation-results-in-vasodilation-of-skeletal-muscles."---
CORRECT-ANSWER-b.-"Beta2-activation-results-in-contraction-of-
uterine-muscle."
10. A-nurse-is-helping-a-nursing-student-who-is-administering-a-medication-to-a-
patient-with-myasthenia-gravis.-Which-statement-by-the-
student-indicates-the-need-for-further-teaching?
, Clayton's Basic Pharmacology for Nurses 19th Edition Unit 3: Drugs
Affecting the Autonomic and Central Nervous Systems Pharmacology
2024 Exam 2 Chapters 12-19
a. "I-will-ask-the-patient-to-sip-some-water-before-giving-the-medication."
b. "I-will-let-the-patient-sleep-after-giving-the-medication,-because-rest-is-
important."
c. "I-will-record-muscle-strength-assessments-before-and-after-I-give-the-
medication."
d.-"I-will-report-excessive-salivation-to-the-patient's-prescriber."---CORRECT-
ANSWER-b.-"I-will-let-the-patient-sleep-after-giving-the-medication,-because-
rest-is-important."
11. A-nurse-is-preparing-to-administer-a-medication-and-learns-that-it-is-a-
nonselective-agonist-drug.-What-does-the-nurse-understand-about-this-drug?
a. It-directly-activates-receptors-to-affect-many-physiologic-processes.
b. It-directly-activates-receptors-to-affect-a-specific-physiologic-process.
c. It-prevents-receptor-activation-to-affect-many-physiologic-processes.
d. It-prevents-receptor-activation-to-affect-a-specific-physiologic-processes.--
-CORRECT-ANSWER-a.-It-directly-activates-receptors-to-affect-many-
physiologic-processes.
12. A-nurse-is-reviewing-nursing-actions-for-emergency-treatment-of-malignant-
hyperthermia-with-a-group-of-nursing-students.-Which-statement-by-a-student-
indicates-a-need-for-further-teaching?
a. "Analgesics-should-be-given-to-help-with-muscle-pain."
b. "Dantrolene-helps-to-slow-the-metabolic-activity-in-skeletal-muscles."
c. "If-malignant-hyperthermia-occurs,-the-succinylcholine-must-be-stopped-
immediately."
d.-"The-patient-may-need-an-intravenous-infusion-of-cold-saline."---CORRECT-
ANSWER-a.-"Analgesics-should-be-given-to-help-with-muscle-pain."
13. A-nurse-is-teaching-a-group-of-nursing-students-about-irreversible-
cholinesterase-inhibitors.-Which-statement-by-a-student-indicates-
understanding-of-theteaching?
a. "Diazepam-is-given-to-reverse-inhibition-of-cholinesterase-when-
overdose-
occurs."
b.-"Irreversible-cholinesterase-inhibitors-are-rapidly-absorbed-by-all-routes."
c.-"These-agents-are-often-used-to-treat-glaucoma."
d.-"Toxic-doses-of-these-agents-produce-an-anticholinergic-crisis."---CORRECT-
ANSWER-b.-"Irreversible-cholinesterase-inhibitors-are-rapidly-absorbed-by-all-
routes."
