Psychopharmacology Drugs the Brain and Behavior 3rd Edition Meyer Test Bank

, Chapter1:PrinciplesofPharmacology d d d d




Multiple Choice d




1. refer(s) to specific molecular changes that occur when a drug binds to a
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particular target site or receptor, while
d d aretheresultingwidespread alterations
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in function.
d d




a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects d d d




d. Drug action; drug effects
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Answer: d d




Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount ofdrug inthe blood that is free to bind
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at specific target sites is referred to as
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a. the therapeutic dose.
d d




b. first-pass effects. d




c. bioavailability.
d. ED50.
Answer: c d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target site or
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receptor are referred to as
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a. drug effects.d




b. drug action. d




c. side effects.
d




d. placebo effects. d




Answer: b d




Textbook Reference: Pharmacology: The Science ofDrug Action
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4. Which ofthe following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning d




b. Genetic variation d




c. Drug competition d




d. Expectation of outcome d d




Answer: c d




Textbook Reference: Pharmacology: The Science ofDrug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. d d d d d d d d d d




a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
d d




b. Lipid solubility
d




c. Depot binding d




d. Drug actiond




Answer: d d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken d d d d d d




a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
d d is not complete. d d d d d d d d d d




a. cerebrospinal fluid d




b. blood–brain barrier d




c. choroid plexus d




d. phospholipid membrane d




Answer: b d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the wayto
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general circulation.
d d




c. drugs must first survive the acidic environment of the stomach.
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d. salivaryenzymes in the mouth begin the process of metabolism.
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Answer: b d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response byactivating the
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a. blood–brain barrier. d




b. choroid plexus. d




c. area postrema.
d




d. median eminence. d




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, Answer: c d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
d d d d d d d d d d ofthe
d




drug.
d




a. pH; pKa
d




b. pKa; pH d




c. concentration; lipid solubility d d




d. pH; concentration
d




Answer: a d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
d




b. ionization.
c. body temperature. d




d. the concentration of the drug.
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Answer: c d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble d




Answer: a d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. d




b. illicit drugs. d




c. teratogens.
d. placental drugs. d




Answer: c d




Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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