Part I: Basic Immunologic Mechanisms
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1. Highlights of Innate and Adaptive Immune Systems f f f f f f
2. Soluble Mediators of the Immune System
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3. Antigens and Antibodies f f
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
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Part II: The Theory of Immunologic and Serologic Procedures
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5. Basic Safety in the Immunology-Serology Laboratory
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6. Quality Assurance and Quality Control Practices
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7. Basic Serologic Laboratory: Techniques and Clinical Applications
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8. Precipitation and Particle Agglutination Methods f f f f
9. Electrophoresis Techniques f
10. Labeling Techniques in Immunoassay f f f
11. Flow Cytometry f
12. Molecular Laboratory Techniques f f
Part III: Immunologic Manifestations of Infectious Diseases
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13. Infectious Diseases: Overview & TORCH Diseases f f f f f
14. Streptococcal Infections f
15. Syphilis
16. Vector-Borne Diseases f
17. Infectious Mononucleosis f
18. Viral Hepatitis f
Part IV: Immune Disorders
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19. Primary and Acquired (Secondary) Immune Deficiencies
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20. Hypersensitivity Reactions f
21. Immunoproliferative Disorders f
22. Tolerance, Autoimmunity and Autoimmune Disorders f f f f
23. Systemic Lupus Erythematosus f f
,24. Rheumatoid Arthritis f
Part V: Transplantation & Tumor Immunology
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25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells f f f f f a f
26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
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Part VI: Vaccines
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27. Primer on Vaccines f f
hapter01:HighlightsoftheInnateandAdaptive ImmuneSystems
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MULTIPLE CHOICE f
1. The―father‖ofimmunologyisgenerallyconsideredto be f f
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B f
Louis Pasteurisgenerallyconsideredto bethe―fatherofimmunology.‖
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DIF: CognitiveLevel:I f f
2. Anearlyform ofimmunizationwaspracticedbythe
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a. Romans.
b. Greeks.
c. Chinese.
d. NativeAmericans. f
ANS: C f
Beginning about1000 AD,theChinesepracticedaformofimmunizationbyinhaling dried powde rs
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derived from the crusts of smallpox lesions.
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DIF: CognitiveLevel:I f f
3. Aspecificfunctionoftheimmunesystemisto
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a. recognizeselffromnonself. f f f
b. defendthebodyagainst nonself. f f f
c. amplifyspecific functions. f
d. BothAand B. f f a
ANS: D f
Thefunctionoftheimmunesystemis to recognizeselffromnonselfanddefendthebodyagainstn onself.
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Suchasystemisnecessaryforsurvival.Theimmunesystemalsohasnonspecificeffector mechanisms
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thatusuallyamplifythespecificfunctions.Nonspecificcomponentsoftheimmunes ystem include
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mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors (e.g.
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,complement).
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DIF: CognitiveLevel:I f f
, 4. Anundesirableconsequenceofimmunityis
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a. naturalresistance.
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b. acquiredresistancetoinfectiousdiseases.
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