NR565 ADVANCED PHARMACOLOGY
MIDTERM EXAM STUDY GUIDE
QUESTIONS & DETAILED CORRECT
ANSWERS
Drugs that APRNs can prescribe - correct answer ✔✔Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - correct answer
✔✔Prescriptive authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
correct answer ✔✔Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
correct answer ✔✔Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin,
Alcohol, Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - correct answer ✔✔BSCRAP GPS
Incudes Rage
Amount of active drug reaching systemic circulation from administration site - correct answer
✔✔Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - correct answer
✔✔Reasons for medication nonadherence
, Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early
infancy - correct answer ✔✔IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
correct answer ✔✔Oral administration in neonates/infants
Based on body surface area (BSA) calculation - correct answer ✔✔Dosage determination for
pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment,
verifying its suitability, starting treatment, giving information, and monitoring treatment -
correct answer ✔✔Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol,
Ketoconazole, Grapefruit juice, Quinidine - correct answer ✔✔CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
correct answer ✔✔Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs
and interactions - correct answer ✔✔Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - correct answer ✔✔Impacts of polypharmacy
They decrease medication metabolism - correct answer ✔✔CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - correct
answer ✔✔CYP450 inhibitors consequences
MIDTERM EXAM STUDY GUIDE
QUESTIONS & DETAILED CORRECT
ANSWERS
Drugs that APRNs can prescribe - correct answer ✔✔Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - correct answer
✔✔Prescriptive authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
correct answer ✔✔Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
correct answer ✔✔Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin,
Alcohol, Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - correct answer ✔✔BSCRAP GPS
Incudes Rage
Amount of active drug reaching systemic circulation from administration site - correct answer
✔✔Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - correct answer
✔✔Reasons for medication nonadherence
, Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early
infancy - correct answer ✔✔IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
correct answer ✔✔Oral administration in neonates/infants
Based on body surface area (BSA) calculation - correct answer ✔✔Dosage determination for
pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment,
verifying its suitability, starting treatment, giving information, and monitoring treatment -
correct answer ✔✔Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol,
Ketoconazole, Grapefruit juice, Quinidine - correct answer ✔✔CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
correct answer ✔✔Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs
and interactions - correct answer ✔✔Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - correct answer ✔✔Impacts of polypharmacy
They decrease medication metabolism - correct answer ✔✔CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - correct
answer ✔✔CYP450 inhibitors consequences
