PSYCHOPHARMACOLOGY DRUGS THE BRAIN AND BEHAVIOR 3RD EDITION MEYER NURSING TEST BANK QUESTIONS AND ANSWERS 2025

TESTBANK
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, Chapter1:PrinciplesofPharmacology v v v v




Multiple Choice v




1. refer(s) to specific molecular changes that occur when a drug binds to a
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particular target site or receptor, while
v v aretheresulting widespread alterations
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in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects v v v




d. Drug action; drug effects
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Answer: d v




Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free to bind
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at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. v




c. bioavailability.
d. ED50.
Answer: c v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target site or
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receptor are referred to as
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a. drugeffects. v




b. drug action. v




c. side effects.
v




d. placebo effects. v




Answer: b v




TextbookReference: Pharmacology: TheScience of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning v




b. Genetic variation v




c. Drug competition v




d. Expectation of outcome v v




Answer: c v




TextbookReference: Pharmacology: The Science of Drug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. v v v v v v v v v v




a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
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b. Lipid solubility
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c. Depot binding v




d. Drugaction v




Answer: d v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken
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a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
v v is not complete. v v v v v v v v v v




a. cerebrospinal fluid v




b. blood–brain barrier v




c. choroid plexus v




d. phospholipid membrane v




Answer: b v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
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general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivaryenzymes in the mouth begin the process of metabolism.
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Answer: b v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. v




b. choroid plexus. v




c. area postrema.
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d. median eminence. v




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, Answer: c v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
v v v v v v v v v v ofthe
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drug.
v




a. pH; pKa
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b. pKa; pH v




c. concentration; lipid solubility v v




d. pH; concentration
v




Answer: a v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
v




b. ionization.
c. body temperature. v




d. the concentration of the drug.
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Answer: c v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble v




Answer: a v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactivedrugs. v




b. illicit drugs. v




c. teratogens.
d. placental drugs. v




Answer: c v




TextbookReference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugsv v v v v v v




a. bind to their target sites.
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