ADN 520: Rheumatoid Arthritis
Questions with 100% Correct Answers
What is autoimmunity? Correct Answer: - Body attacks itself
- Chron's disease
- Type I diabetes
- Fibromyalgia
What are risk factors for developing an autoimmune disoder? Correct Answer: -
Stress
- Female
- Older age
- High fat diet
- Certain medications
- Already having an autoimmune disorder
What is the number one clinical finding for a patient with an autoimmune
disorder? Correct Answer: - Fatigue
What is serological testing? Correct Answer: - Blood test
- ELISA
- Antibodies to specific tissue antigens
, What labs should you monitor on a patient with an autoimmune disorder and
why? Correct Answer: - WBC: increased due to inflammation, decreased due to
immunosuppression or lupus
- ESR: measures proteins
- CRP: looks at specific protein to to determine inflammation, effectiveness of
meds
- Hct: decreased due to decreased RBCs
- Creatinine: increased due to kidneys processing inflammation
- RBC count: decreased due to anemia because inflammation destroys RBCs
- Liver and kidney function: immunosuppressants hard on both
What medications are used to treat general autoimmune disorders? Correct
Answer: - Corticosteroids- block lymphocytes from producing antibodies and
neutrophils from functioning
- Monoclonal antibodies- modified to make B-cells target T-cells
- Non-biological disease modifying antireumatic drugs- immunosuppressants,
chemotherapy wipe out rapidly growing cells
- Aspirin/NSAIDs- heart health
Why are corticosteroids only used for short term therapy? Correct Answer: -
Have extreme side effects
What are potential side effects from using corticosteroids for a long period of
time? Correct Answer: - Osteoporosis
Questions with 100% Correct Answers
What is autoimmunity? Correct Answer: - Body attacks itself
- Chron's disease
- Type I diabetes
- Fibromyalgia
What are risk factors for developing an autoimmune disoder? Correct Answer: -
Stress
- Female
- Older age
- High fat diet
- Certain medications
- Already having an autoimmune disorder
What is the number one clinical finding for a patient with an autoimmune
disorder? Correct Answer: - Fatigue
What is serological testing? Correct Answer: - Blood test
- ELISA
- Antibodies to specific tissue antigens
, What labs should you monitor on a patient with an autoimmune disorder and
why? Correct Answer: - WBC: increased due to inflammation, decreased due to
immunosuppression or lupus
- ESR: measures proteins
- CRP: looks at specific protein to to determine inflammation, effectiveness of
meds
- Hct: decreased due to decreased RBCs
- Creatinine: increased due to kidneys processing inflammation
- RBC count: decreased due to anemia because inflammation destroys RBCs
- Liver and kidney function: immunosuppressants hard on both
What medications are used to treat general autoimmune disorders? Correct
Answer: - Corticosteroids- block lymphocytes from producing antibodies and
neutrophils from functioning
- Monoclonal antibodies- modified to make B-cells target T-cells
- Non-biological disease modifying antireumatic drugs- immunosuppressants,
chemotherapy wipe out rapidly growing cells
- Aspirin/NSAIDs- heart health
Why are corticosteroids only used for short term therapy? Correct Answer: -
Have extreme side effects
What are potential side effects from using corticosteroids for a long period of
time? Correct Answer: - Osteoporosis