MDT EXAM 1 - PART 1 QUESTIONS &
VERIFIED ANSWERS 100%
ACCURATE
discuss the impact of molecular diagnostics in human disease - correct answer ✔✔More
accurate disease monitoring - allows for early treatment and improved patient care
Determination of most appropriate treatment
Reduction of patient morbidity and mortality
Able to diagnose and prognosis that patient
*** Example someone might have a HER2 gene amplification but we have a great medication to
use despite the fact that this type of breast cancer is aggressive
define molecular diagnostics - correct answer ✔✔- Molecular diagnostics encompasses the use
of molecular biology techniques to expand scientific knowledge of the natural history of disease
- Can help identify people at risk for acquiring specific diseases and facilitates the diagnosis of
infectious and other human diseases at the nucleic level
- Molecular testing went from being its own thing to being a part of many lab practices
importance of nucleic acids in the lab - correct answer ✔✔-Assay exhibit extreme sensitivity
and specificity (which can be controlled)
, -Genotype before phenotype
-Targets can be amplified >10^6 --- assays like a photocopier so we can find the targets we are
interested in
describe utility of molecular pathology in laboratory medicine - correct answer ✔✔- Assays are
developed based on the presence of specific molecular markers
-Diagnostic test -- distinguish variations in human disease
- Prognostic tests -- accurately describe the course of disease
- Therapeutic tests -- predict the response to specific therapies and determine if therapy is
effective
list applications for genomic technologies - correct answer ✔✔Molecular diagnostics is a
universal discipline of laboratory medicine
Genetics - heritable diseases
Oncology - solid tumors
Hematopathology - leukemia and lymphoma
Identity Testing - transplantation and forensics
VERIFIED ANSWERS 100%
ACCURATE
discuss the impact of molecular diagnostics in human disease - correct answer ✔✔More
accurate disease monitoring - allows for early treatment and improved patient care
Determination of most appropriate treatment
Reduction of patient morbidity and mortality
Able to diagnose and prognosis that patient
*** Example someone might have a HER2 gene amplification but we have a great medication to
use despite the fact that this type of breast cancer is aggressive
define molecular diagnostics - correct answer ✔✔- Molecular diagnostics encompasses the use
of molecular biology techniques to expand scientific knowledge of the natural history of disease
- Can help identify people at risk for acquiring specific diseases and facilitates the diagnosis of
infectious and other human diseases at the nucleic level
- Molecular testing went from being its own thing to being a part of many lab practices
importance of nucleic acids in the lab - correct answer ✔✔-Assay exhibit extreme sensitivity
and specificity (which can be controlled)
, -Genotype before phenotype
-Targets can be amplified >10^6 --- assays like a photocopier so we can find the targets we are
interested in
describe utility of molecular pathology in laboratory medicine - correct answer ✔✔- Assays are
developed based on the presence of specific molecular markers
-Diagnostic test -- distinguish variations in human disease
- Prognostic tests -- accurately describe the course of disease
- Therapeutic tests -- predict the response to specific therapies and determine if therapy is
effective
list applications for genomic technologies - correct answer ✔✔Molecular diagnostics is a
universal discipline of laboratory medicine
Genetics - heritable diseases
Oncology - solid tumors
Hematopathology - leukemia and lymphoma
Identity Testing - transplantation and forensics
