TEST BANK FOR
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
Chapter 1-27
,Chapter 01: Highlights of the Innate and Adaptive Immune Systems
MULTIPLE CHOICE
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the ―father of immunology.‖
DIF: Cognitive Level: I
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling drie
d powders derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has n
onspecific effector mechanisms that usually amplify the specific functions. Nonspecific co
mponents of the immune system include mononuclear phagocytes, polymorphonuclear leu
kocytes, and soluble factors (e.g., complement).
DIF: Cognitive Level: I
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
, c. an autoimmune disorder.
d. recovery from infectious disease.
ANS: C
The desirable consequences of immunity include natural resistance, recovery, and acquired
resistance to infectious diseases. A deficiency or dysfunction of the immune system can c
ause many disorders. Undesirable consequences of immunity include allergy, rejection of
a transplanted organ, or an autoimmune disorder.
DIF: Cognitive Level: I
5. The immune system has various distinctive characteristics except;
a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells.
ANS: D
The immune system is composed of a large, complex set of widely distributed elements,
with the distinctive characteristics of specificity, memory, mobility, replicability, and coop
eration among different cells or cellular products. Specificity and memory are characteristi
cs of lymphocytes in the immune system. Nonspecific elements of the immune system de
monstrate mobility. In addition, specific and nonspecific cellular components of the immu
ne system can replicate. Cooperation is required for optimal functioning, and interaction i
nvolves specific cellular elements, cell products, and nonlymphoid elements.
DIF: Cognitive Level: I
6. Hematopoiesis occurs in the yolk sac during the
a. immediate hours after conception
b. second month of gestation.
c. second trimester of gestation.
d. periods of severe anemia in children.
ANS: A
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the e
mbryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestati
on.
DIF: Cognitive Level: II
7. The sequence of blood cell development in the embryo and fetus is
a. yolk sac, liver-spleen, bone marrow.
b. yolk sac, bone marrow, liver/spleen.
c. liver-spleen, yolk sac, bone marrow.
d. bone marrow, liver-spleen, yolk sac.
ANS: A
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the isl
ets of the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen
replace the yolk sac as the sites of blood cell development. By the second month of ges
tation, the liver becomes the major site of hematopoiesis, and granular types of leukocyt
es have made their initial appearance. The liver and spleen predominate from about 2 to
5 months of fetal life. In the fourth month of gestation, bone marrow begins to produce
blood cells. After the fifth fetal month, bone marrow begins to assume its ultimate role
as the primary site of hematopoiesis.
DIF: Cognitive Level: II
8. The primary function of mature neutrophils is
a. to reduce inflammation.
b. to lyse parasites in the circulatory system.
c. antigen recognition.
d. phagocytosis.
ANS: D
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestina
l system, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of i
njury and can be found in the initial exudate in less than 1 hour. Monocytes are slower i
n moving to the inflammatory site. Macrophages resident in the tissues of the body are al
ready in place to deal with an intruding agent. Additional macrophages from the bone mar
row and other tissues can be released in severe infections.
DIF: Cognitive Level: II
9. Primary granules, or azurophilic granules, in neutrophils contain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B.
ANS: D
Granules in the phagocyte cytosol contain degradatory enzymes of three types
1. Primary, or azurophilic, granules containing enzymes (e.g., lysozy
me, myeloperoxidase)
2. Secondary, or specific, granules containing substances such as lactoferrin.
3. Tertiary granules containing substances such as caspases
DIF: Cognitive Level: I
10. The origin of a condition when eosinophils are increased in the circulating blood is asso
ciated with:
a. fungus
b. parasitic amoeba
c. allergic reactions
d. bacteria
ANS: C
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
Chapter 1-27
,Chapter 01: Highlights of the Innate and Adaptive Immune Systems
MULTIPLE CHOICE
1. The ―father‖ of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the ―father of immunology.‖
DIF: Cognitive Level: I
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling drie
d powders derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body
against nonself. Such a system is necessary for survival. The immune system also has n
onspecific effector mechanisms that usually amplify the specific functions. Nonspecific co
mponents of the immune system include mononuclear phagocytes, polymorphonuclear leu
kocytes, and soluble factors (e.g., complement).
DIF: Cognitive Level: I
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
, c. an autoimmune disorder.
d. recovery from infectious disease.
ANS: C
The desirable consequences of immunity include natural resistance, recovery, and acquired
resistance to infectious diseases. A deficiency or dysfunction of the immune system can c
ause many disorders. Undesirable consequences of immunity include allergy, rejection of
a transplanted organ, or an autoimmune disorder.
DIF: Cognitive Level: I
5. The immune system has various distinctive characteristics except;
a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells.
ANS: D
The immune system is composed of a large, complex set of widely distributed elements,
with the distinctive characteristics of specificity, memory, mobility, replicability, and coop
eration among different cells or cellular products. Specificity and memory are characteristi
cs of lymphocytes in the immune system. Nonspecific elements of the immune system de
monstrate mobility. In addition, specific and nonspecific cellular components of the immu
ne system can replicate. Cooperation is required for optimal functioning, and interaction i
nvolves specific cellular elements, cell products, and nonlymphoid elements.
DIF: Cognitive Level: I
6. Hematopoiesis occurs in the yolk sac during the
a. immediate hours after conception
b. second month of gestation.
c. second trimester of gestation.
d. periods of severe anemia in children.
ANS: A
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the e
mbryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestati
on.
DIF: Cognitive Level: II
7. The sequence of blood cell development in the embryo and fetus is
a. yolk sac, liver-spleen, bone marrow.
b. yolk sac, bone marrow, liver/spleen.
c. liver-spleen, yolk sac, bone marrow.
d. bone marrow, liver-spleen, yolk sac.
ANS: A
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the isl
ets of the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen
replace the yolk sac as the sites of blood cell development. By the second month of ges
tation, the liver becomes the major site of hematopoiesis, and granular types of leukocyt
es have made their initial appearance. The liver and spleen predominate from about 2 to
5 months of fetal life. In the fourth month of gestation, bone marrow begins to produce
blood cells. After the fifth fetal month, bone marrow begins to assume its ultimate role
as the primary site of hematopoiesis.
DIF: Cognitive Level: II
8. The primary function of mature neutrophils is
a. to reduce inflammation.
b. to lyse parasites in the circulatory system.
c. antigen recognition.
d. phagocytosis.
ANS: D
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestina
l system, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of i
njury and can be found in the initial exudate in less than 1 hour. Monocytes are slower i
n moving to the inflammatory site. Macrophages resident in the tissues of the body are al
ready in place to deal with an intruding agent. Additional macrophages from the bone mar
row and other tissues can be released in severe infections.
DIF: Cognitive Level: II
9. Primary granules, or azurophilic granules, in neutrophils contain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B.
ANS: D
Granules in the phagocyte cytosol contain degradatory enzymes of three types
1. Primary, or azurophilic, granules containing enzymes (e.g., lysozy
me, myeloperoxidase)
2. Secondary, or specific, granules containing substances such as lactoferrin.
3. Tertiary granules containing substances such as caspases
DIF: Cognitive Level: I
10. The origin of a condition when eosinophils are increased in the circulating blood is asso
ciated with:
a. fungus
b. parasitic amoeba
c. allergic reactions
d. bacteria
ANS: C
