· on there
basement membrane
·
cells escape
Difference between acute and chronic:
-
● · follows blood oxygen
+
circulati
guaranteed
in
602 survival not
O○ Onset abrupt vs slow supply angiogenes
&
limited by
blood · tumor growth
angiogenesis grow
:
● Metastasis: >
-
to
○ vascular/lymphatic flow (cells escape cell of origin and create new colonies)
○ Lymphatic has more of a pathway; builds its own blood supply I can go to atypical
O sites ?
● Chronic Myeloid L:
○ High granulocyte count on CBC w/diff +
philadelphia a
● Confirmative DX:
○ Bone marrow aspiration confirms CA
ALL:
Cells ●
○ Malignant transfromation of B-cells >
-
younger
Fids 3-7
● MMyeloma: IN liver spuen
,
,
kidneys
mismo
*
○ Hypercalcemia,②
bone lesions, bone pain, Bence Jones protein in urine
○ Seen in CKD (kidney dysfunction) - L
-
○ Hyperviscosity of blood because of dehydration, anemia, decreased WBC(risk
for infection) >
- confirmation
=
bone marrow biopsy
● How HIV:
f GI is the primary site
*
○ is
○ RNA virus that needs reverse transcriptase, integrase, protease
·
ot
i○ O
⑧ Affects"
CD4+ cells (lymphocytes and macrophages)
○ Infections with AIDS: Candidiasis (oral/vaginal)= DC and itching, thrush, + PID
-
pneumocystis pneumonia, TB (late afternoon temp, night sweats, unexplained
weight loss cough
weight loss, cough) + wasting syndrome- 7
, ,
mu
○ HX of HIV come in with pneumonia? It has turned into AIDS**
● Hodgkins: * Reed Sternberg cells
○
O Lymphadenopathy in the cervical and supraclavicular, mediastinal, axillary
■ Enlarged because of accumulation of inflammatory cells
note
Non-Hodkins:
in the
● cells accumulate
>
-
○ Any lymph node is involved *
tract
in gi
○ Lymphoid tissue* that grows on organs
O
○ Spinal cord compression and Superior vena cava= complications
● Acute Myeloid Leukemia:
○ Patho process: immature blast cells cant differentiate into specific type cells
■ Bone pain, anemia, high WBC, etc.
● Scleroderma:
○ Large quantity of collagenous tissue that is deposited into connective tissue =
hardening 7 ↳ inflammation
vascular-pathy/injury
-
vessel wall
-
t
thickening
ischemia
basement membrane
·
cells escape
Difference between acute and chronic:
-
● · follows blood oxygen
+
circulati
guaranteed
in
602 survival not
O○ Onset abrupt vs slow supply angiogenes
&
limited by
blood · tumor growth
angiogenesis grow
:
● Metastasis: >
-
to
○ vascular/lymphatic flow (cells escape cell of origin and create new colonies)
○ Lymphatic has more of a pathway; builds its own blood supply I can go to atypical
O sites ?
● Chronic Myeloid L:
○ High granulocyte count on CBC w/diff +
philadelphia a
● Confirmative DX:
○ Bone marrow aspiration confirms CA
ALL:
Cells ●
○ Malignant transfromation of B-cells >
-
younger
Fids 3-7
● MMyeloma: IN liver spuen
,
,
kidneys
mismo
*
○ Hypercalcemia,②
bone lesions, bone pain, Bence Jones protein in urine
○ Seen in CKD (kidney dysfunction) - L
-
○ Hyperviscosity of blood because of dehydration, anemia, decreased WBC(risk
for infection) >
- confirmation
=
bone marrow biopsy
● How HIV:
f GI is the primary site
*
○ is
○ RNA virus that needs reverse transcriptase, integrase, protease
·
ot
i○ O
⑧ Affects"
CD4+ cells (lymphocytes and macrophages)
○ Infections with AIDS: Candidiasis (oral/vaginal)= DC and itching, thrush, + PID
-
pneumocystis pneumonia, TB (late afternoon temp, night sweats, unexplained
weight loss cough
weight loss, cough) + wasting syndrome- 7
, ,
mu
○ HX of HIV come in with pneumonia? It has turned into AIDS**
● Hodgkins: * Reed Sternberg cells
○
O Lymphadenopathy in the cervical and supraclavicular, mediastinal, axillary
■ Enlarged because of accumulation of inflammatory cells
note
Non-Hodkins:
in the
● cells accumulate
>
-
○ Any lymph node is involved *
tract
in gi
○ Lymphoid tissue* that grows on organs
O
○ Spinal cord compression and Superior vena cava= complications
● Acute Myeloid Leukemia:
○ Patho process: immature blast cells cant differentiate into specific type cells
■ Bone pain, anemia, high WBC, etc.
● Scleroderma:
○ Large quantity of collagenous tissue that is deposited into connective tissue =
hardening 7 ↳ inflammation
vascular-pathy/injury
-
vessel wall
-
t
thickening
ischemia
