,MULTIPLERCHOICE
1. ARstudentRisRobservingRaRcellRunderRtheRmicroscope.RItRisRobservedRtoRhaveRsupercoiledRDN
ARwithRhistones.RWhichRofRtheRfollowingRwouldRalsoRbeRobservedRbyRtheRstudent?
a. ARsingleRcircularRchromosome
b. ARnucleus
c. Free-floatingRnuclearRmaterial
d. NoRorganelles
ANS:R B
TheRcellRdescribedRisRaReukaryoticRcell,RsoRitRhasRhistonesRandRaRsupercoiledRDNARwithinRitsRn
ucleus;Rthus,RtheRnucleusRshouldRbeRobserved.RARsingleRcircularRchromosomeRcalledRaRprokary
oteRcontainsRfree-floatingRnuclearRmaterialRbutRhasRnoRorganelles.
REF:R p.R2
2. ARnurseRisRinstructingRtheRstaffRaboutRcellularRfunctions.RWhichRcellularRfunctionRisRtheRnurse
RdescribingRwhenRanRisolatedRcellRabsorbsRoxygenRandRusesRitRtoRtransformRnutrientsRtoRenerg
y?
a. MetabolicRabsorption
b. Communication
c. Secretion
d. Respiration
ANS:R D
TheRcell’sRabilityRtoRabsorbRoxygenRisRreferredRtoRasRrespirationRwhileRitsRcommunicationRabilityRin
volvesRmaintenanceRofRaRsteadyRdynamicRstate,RmetabolicRabsorptionRprovidesRnutrition,RandRsecre
tionRallowsRforRtheRsynthesizingRofRnewRsubstances.
REF:R p.R2
3. AReukaryoticRcellRisRundergoingRDNARreplication.RInRwhichRregionRofRtheRcellRwouldRmostRo
fRtheRgeneticRinformationRbeRcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusRCytoplasm
ANS:R C
TheRregionRofRtheRcellRthatRcontainsRgeneticRmaterial,RincludingRaRlargeRamountRofRribonucleicR
acid,RmostRofRtheRDNA,RandRDNA-
bindingRproteins,RisRtheRnucleolus,RwhichRisRlocatedRwithinRtheRcell’sRnucleus.RMitochondriaRis
RassociatedRwithRcellularRrespiration,RwhileRribosomesRareRinvolvedRwithRproteinRmanufacturin
g.RCytoplasmRisRaRfluidRfillingRthatRisRaRcomponentRofRtheRcell.
REF:R p.R2
,4. WhichRofRtheRfollowingRcanRremoveRproteinsRattachedRtoRtheRcell’sRbilayerRbyRdissolvingRth
eRlayerRitself?
a. PeripheralRmembraneRproteins
b. IntegralRmembraneRproteins
c. Glycoproteins
d. CellRadhesionRmolecules
ANS:R B
ProteinsRdirectlyRattachedRtoRtheRmembraneRbilayerRcanRbeRremovedRbyRtheRactionRofRintegralR
membraneRproteinsRthatRdissolveRtheRbilayer.RPeripheralRmembraneRproteinsRresideRatRtheRsurf
aceRwhileRcellRadhesionRmoleculesRareRonRtheRoutsideRofRtheRmembrane.RGlycoproteinRmarksR
cellsRandRdoesRnotRfloat.
REF:R p.R7
5. WhichRofRtheRfollowingRcanRbindRtoRplasmaRmembraneRreceptors?
a. Oxygen
b. Ribosomes
c. AmphipathicRlipids
d. Ligands
ANS:R D
LigandsRareRtheRonlyRspecificRmoleculesRthatRcanRbindRwithRreceptorsRonRtheRcellRmembrane.
REF:R p.R9
6. ARnurseRisRreviewingRaRreportRfromRaRpatientRwithRmetastaticRcancer.RWhatRalternationRinRth
eRextracellularRmatrixRwouldRs uNpUpRS
oRr t Rt hIe RdG
RNRT
iagnBo.
siC
sRofM
metastaticRcancer?
a. DecreasedRfibronectin
b. IncreasedRcollagen
c. DecreasedRelastin
d. IncreasedRglycoproteins
ANS:R A
OnlyRaRreducedRamountRofRfibronectinRisRfoundRinRsomeRtypesRofRcancerousRcells,RallowingRthe
mRtoRtravelRorRmetastasize.
REF:R p.R10
7. WhichRformRofRcellRcommunicationRisRusedRtoRrelateRtoRotherRcellsRinRdirectRphysicalRcontact?
a. CellRjunction
b. GapRjunction
c. Desmosome
d. TightRjunction
ANS:R A
CellRjunctionsRholdRcellsRtogetherRandRpermitRmoleculesRtoRpassRfromRcellRtoRcell.
GapRjunctionsRallowRforRcellularRcommunicationRbetweenRcells.RNeitherRdesmosomesRnorRtightRjun
ctionsRareRassociatedRwithRcellularRcommunication.
REF:R p.R11
, 8. PancreaticRbetaRcellsRsecreteRinsulin,RwhichRinhibitsRsecretionRofRglucagonRfromRneighborin
gRalphaRcells.RThisRactionRisRanRexampleRofRwhichRofRtheRfollowingRsignalingRtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:R A
ParacrineRsignalingRinvolvesRtheRreleaseRofRlocalRchemicalRmediatorsRthatRareRquicklyRtakenRup,
Rdestroyed,RorRimmobilized,RasRinRtheRcaseRofRinsulinRandRtheRinhibitionRofRtheRsecretionRofRglu
cagon.RNoneRofRtheRotherRoptionsRinvolveRsignalingRthatRisRassociatedRwithRaRlocalRchemicalRm
ediatorRlikeRinsulin.
REF:R p.R12
9. InRcellularRmetabolism,ReachRenzymeRhasRaRhighRaffinityRforRa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:R B
EachRenzymeRhasRaRhighRaffinityRforRaRsubstrate,RaRspecificRsubstanceRconvertedRtoRaRproductRo
fRtheRreaction.RCellularRmetabolismRisRnotRdependentRonRanRattractionRbetweenRanRenzymeRand
RanyRofRtheRremainingRoptions.
REF:R R p.R16
10. AnRathleteRrunsRaRmarathon,RafterRwhichRhisRmusclesRfeelRfatiguedRandRunableRtoRcontract.RThe
RathleteRasksRtheRnurseRwhyRthisRhappened.RTheRnurse’sRresponseRisRbasedRonRtheRknowledgeRth
atRtheRproblemRisRresultRofRaRdeficiencyRof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:R C
WhenRATPRisRdeficient,RimpairedRmuscleRcontractionRresults.RNoneRofRtheRotherRoptionsRareRin
volvedRinRmuscleRcontraction.
REF:R p.R16
11. WhichRphaseRofRcatabolismRproducesRtheRmostRATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. CitricRacidRcycle
ANS:R D
WhileRsomeRATPRisRproducedRduringRtheRoxidationRandRglycolysisRphases,RmostRofRtheRATPRis
1. ARstudentRisRobservingRaRcellRunderRtheRmicroscope.RItRisRobservedRtoRhaveRsupercoiledRDN
ARwithRhistones.RWhichRofRtheRfollowingRwouldRalsoRbeRobservedRbyRtheRstudent?
a. ARsingleRcircularRchromosome
b. ARnucleus
c. Free-floatingRnuclearRmaterial
d. NoRorganelles
ANS:R B
TheRcellRdescribedRisRaReukaryoticRcell,RsoRitRhasRhistonesRandRaRsupercoiledRDNARwithinRitsRn
ucleus;Rthus,RtheRnucleusRshouldRbeRobserved.RARsingleRcircularRchromosomeRcalledRaRprokary
oteRcontainsRfree-floatingRnuclearRmaterialRbutRhasRnoRorganelles.
REF:R p.R2
2. ARnurseRisRinstructingRtheRstaffRaboutRcellularRfunctions.RWhichRcellularRfunctionRisRtheRnurse
RdescribingRwhenRanRisolatedRcellRabsorbsRoxygenRandRusesRitRtoRtransformRnutrientsRtoRenerg
y?
a. MetabolicRabsorption
b. Communication
c. Secretion
d. Respiration
ANS:R D
TheRcell’sRabilityRtoRabsorbRoxygenRisRreferredRtoRasRrespirationRwhileRitsRcommunicationRabilityRin
volvesRmaintenanceRofRaRsteadyRdynamicRstate,RmetabolicRabsorptionRprovidesRnutrition,RandRsecre
tionRallowsRforRtheRsynthesizingRofRnewRsubstances.
REF:R p.R2
3. AReukaryoticRcellRisRundergoingRDNARreplication.RInRwhichRregionRofRtheRcellRwouldRmostRo
fRtheRgeneticRinformationRbeRcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusRCytoplasm
ANS:R C
TheRregionRofRtheRcellRthatRcontainsRgeneticRmaterial,RincludingRaRlargeRamountRofRribonucleicR
acid,RmostRofRtheRDNA,RandRDNA-
bindingRproteins,RisRtheRnucleolus,RwhichRisRlocatedRwithinRtheRcell’sRnucleus.RMitochondriaRis
RassociatedRwithRcellularRrespiration,RwhileRribosomesRareRinvolvedRwithRproteinRmanufacturin
g.RCytoplasmRisRaRfluidRfillingRthatRisRaRcomponentRofRtheRcell.
REF:R p.R2
,4. WhichRofRtheRfollowingRcanRremoveRproteinsRattachedRtoRtheRcell’sRbilayerRbyRdissolvingRth
eRlayerRitself?
a. PeripheralRmembraneRproteins
b. IntegralRmembraneRproteins
c. Glycoproteins
d. CellRadhesionRmolecules
ANS:R B
ProteinsRdirectlyRattachedRtoRtheRmembraneRbilayerRcanRbeRremovedRbyRtheRactionRofRintegralR
membraneRproteinsRthatRdissolveRtheRbilayer.RPeripheralRmembraneRproteinsRresideRatRtheRsurf
aceRwhileRcellRadhesionRmoleculesRareRonRtheRoutsideRofRtheRmembrane.RGlycoproteinRmarksR
cellsRandRdoesRnotRfloat.
REF:R p.R7
5. WhichRofRtheRfollowingRcanRbindRtoRplasmaRmembraneRreceptors?
a. Oxygen
b. Ribosomes
c. AmphipathicRlipids
d. Ligands
ANS:R D
LigandsRareRtheRonlyRspecificRmoleculesRthatRcanRbindRwithRreceptorsRonRtheRcellRmembrane.
REF:R p.R9
6. ARnurseRisRreviewingRaRreportRfromRaRpatientRwithRmetastaticRcancer.RWhatRalternationRinRth
eRextracellularRmatrixRwouldRs uNpUpRS
oRr t Rt hIe RdG
RNRT
iagnBo.
siC
sRofM
metastaticRcancer?
a. DecreasedRfibronectin
b. IncreasedRcollagen
c. DecreasedRelastin
d. IncreasedRglycoproteins
ANS:R A
OnlyRaRreducedRamountRofRfibronectinRisRfoundRinRsomeRtypesRofRcancerousRcells,RallowingRthe
mRtoRtravelRorRmetastasize.
REF:R p.R10
7. WhichRformRofRcellRcommunicationRisRusedRtoRrelateRtoRotherRcellsRinRdirectRphysicalRcontact?
a. CellRjunction
b. GapRjunction
c. Desmosome
d. TightRjunction
ANS:R A
CellRjunctionsRholdRcellsRtogetherRandRpermitRmoleculesRtoRpassRfromRcellRtoRcell.
GapRjunctionsRallowRforRcellularRcommunicationRbetweenRcells.RNeitherRdesmosomesRnorRtightRjun
ctionsRareRassociatedRwithRcellularRcommunication.
REF:R p.R11
, 8. PancreaticRbetaRcellsRsecreteRinsulin,RwhichRinhibitsRsecretionRofRglucagonRfromRneighborin
gRalphaRcells.RThisRactionRisRanRexampleRofRwhichRofRtheRfollowingRsignalingRtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:R A
ParacrineRsignalingRinvolvesRtheRreleaseRofRlocalRchemicalRmediatorsRthatRareRquicklyRtakenRup,
Rdestroyed,RorRimmobilized,RasRinRtheRcaseRofRinsulinRandRtheRinhibitionRofRtheRsecretionRofRglu
cagon.RNoneRofRtheRotherRoptionsRinvolveRsignalingRthatRisRassociatedRwithRaRlocalRchemicalRm
ediatorRlikeRinsulin.
REF:R p.R12
9. InRcellularRmetabolism,ReachRenzymeRhasRaRhighRaffinityRforRa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:R B
EachRenzymeRhasRaRhighRaffinityRforRaRsubstrate,RaRspecificRsubstanceRconvertedRtoRaRproductRo
fRtheRreaction.RCellularRmetabolismRisRnotRdependentRonRanRattractionRbetweenRanRenzymeRand
RanyRofRtheRremainingRoptions.
REF:R R p.R16
10. AnRathleteRrunsRaRmarathon,RafterRwhichRhisRmusclesRfeelRfatiguedRandRunableRtoRcontract.RThe
RathleteRasksRtheRnurseRwhyRthisRhappened.RTheRnurse’sRresponseRisRbasedRonRtheRknowledgeRth
atRtheRproblemRisRresultRofRaRdeficiencyRof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:R C
WhenRATPRisRdeficient,RimpairedRmuscleRcontractionRresults.RNoneRofRtheRotherRoptionsRareRin
volvedRinRmuscleRcontraction.
REF:R p.R16
11. WhichRphaseRofRcatabolismRproducesRtheRmostRATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. CitricRacidRcycle
ANS:R D
WhileRsomeRATPRisRproducedRduringRtheRoxidationRandRglycolysisRphases,RmostRofRtheRATPRis