NR 565 MIDTERM Study Guide

Chapter 2. Review of Basic Principles of Pharmacology 1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to prescribing because: Distribution of drugs to target tissue may be affected. 2. Drugs that have a significant first-pass effect: Are rapidly metabolized by the liver and may have little if any desired action 3.The route of excretion of a volatile drug will likely be the: Lungs 4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir Increase the length of time a drug is available and active 5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s: Biological half-life 6. Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose: Rapidly achieves drug levels in the therapeutic range 7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: Onset of action 8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done: To determine if a drug is in the therapeutic range 9. A laboratory result indicates that the peak level for a drug is above the minimum toxic