1. The structure of human serum albumin may be described as a series of large (L)
and small (S) double loops. How are these arranged in each of the three
domains?
(2 marks)
2. Name two drugs which human serum albumin can bind to and transport as part
of the normal activities of the protein and which do not require modification of
the albumin.
i)
ii)
iii)
3. What are the shapes of the oxygen saturation curve for (i) myoglobin, and (ii) haemoglobin?
(2 marks)
i)
ii)
4. Name three allosteric regulators of the binding of oxygen to haemoglobin. (3 marks)
i)
ii)
iii)
5. The diagram opposite represents the
change in free energy during an
uncatalysed chemical reaction. Add a
Free energy
line to the diagram to indicate the
possible progression of the same
reaction when catalysed by an enzyme.
(2 marks)
Reaction progress
6. A non-protein component of an enzyme is called a
(1 mark)
and small (S) double loops. How are these arranged in each of the three
domains?
(2 marks)
2. Name two drugs which human serum albumin can bind to and transport as part
of the normal activities of the protein and which do not require modification of
the albumin.
i)
ii)
iii)
3. What are the shapes of the oxygen saturation curve for (i) myoglobin, and (ii) haemoglobin?
(2 marks)
i)
ii)
4. Name three allosteric regulators of the binding of oxygen to haemoglobin. (3 marks)
i)
ii)
iii)
5. The diagram opposite represents the
change in free energy during an
uncatalysed chemical reaction. Add a
Free energy
line to the diagram to indicate the
possible progression of the same
reaction when catalysed by an enzyme.
(2 marks)
Reaction progress
6. A non-protein component of an enzyme is called a
(1 mark)
