Portage Pathophysiology Module 10 Mock Exam 2026 |
Trusted Questions & Answers
1. If a patient has a deficiency in proteoglycans in their articular cartilage, what
symptoms might they experience related to joint function?
Increased joint pain and reduced mobility due to decreased
resistance to compression forces.
No noticeable symptoms.
Increased joint stability and reduced inflammation.
Improved joint flexibility and strength.
2. Describe the significance of underexcretion of urate in the context of gout
diagnosis.
Underexcretion of urate means the patient is likely dehydrated.
Underexcretion of urate is unrelated to gout and indicates normal
kidney function.
Underexcretion of urate suggests that the body is producing too
much uric acid.
Underexcretion of urate indicates that the kidneys are not
eliminating enough uric acid, contributing to elevated serum levels
and potential gout attacks.
3. A 45-year-old man comes to the ER with a red, painful, and swollen big toe.
His uric acid level is elevated. What is the patient presenting with?
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Gouty arthritis
, Osteoarthritis
4. What are two common physical exam findings in a patient suspected of
having osteoarthritis (OA)?
muscle atrophy and weakness
swelling and redness
increased range of motion
capsular pattern, crepitus with movement
5. Which form of vitamin D3 is produced in the liver?
1-OH D3
1,25-OH D3
24, 25-OH D3
7-OH-kalciferol
25-OH D3
6. Lady with painful, swollen knee, ankle, shoulder and symmetrical PIPs. Which
symptom indicates RA over OA?
Red and swollen joints
More larger joints affected than smaller joints
Symmetrical PIPs were affected
7. Describe how premature birth can contribute to the development of
osteoporosis.
Premature birth only affects muscle development.
, Premature birth can lead to underdeveloped bones, increasing the
risk of osteoporosis.
Premature birth has no effect on bone health.
Premature birth strengthens bone density.
8. What is the primary role of proteoglycans in articular cartilage?
Facilitate joint movement
Resist compression forces
Store calcium
Provide tensile strength
9. Describe how prolonged immobilization can affect joint health and
potentially lead to osteoarthritis.
Prolonged immobilization has no effect on joint health.
Prolonged immobilization only affects muscle strength, not joint
health.
Prolonged immobilization can lead to decreased joint lubrication
and increased stiffness, contributing to the development of
osteoarthritis.
Prolonged immobilization strengthens the joint and prevents
osteoarthritis.
10. Describe the role of osteoprotegerin (OPG) in bone metabolism and how it
might be affected in a young athlete with amenorrhea.
OPG is primarily involved in muscle metabolism rather than bone
health.
Trusted Questions & Answers
1. If a patient has a deficiency in proteoglycans in their articular cartilage, what
symptoms might they experience related to joint function?
Increased joint pain and reduced mobility due to decreased
resistance to compression forces.
No noticeable symptoms.
Increased joint stability and reduced inflammation.
Improved joint flexibility and strength.
2. Describe the significance of underexcretion of urate in the context of gout
diagnosis.
Underexcretion of urate means the patient is likely dehydrated.
Underexcretion of urate is unrelated to gout and indicates normal
kidney function.
Underexcretion of urate suggests that the body is producing too
much uric acid.
Underexcretion of urate indicates that the kidneys are not
eliminating enough uric acid, contributing to elevated serum levels
and potential gout attacks.
3. A 45-year-old man comes to the ER with a red, painful, and swollen big toe.
His uric acid level is elevated. What is the patient presenting with?
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Gouty arthritis
, Osteoarthritis
4. What are two common physical exam findings in a patient suspected of
having osteoarthritis (OA)?
muscle atrophy and weakness
swelling and redness
increased range of motion
capsular pattern, crepitus with movement
5. Which form of vitamin D3 is produced in the liver?
1-OH D3
1,25-OH D3
24, 25-OH D3
7-OH-kalciferol
25-OH D3
6. Lady with painful, swollen knee, ankle, shoulder and symmetrical PIPs. Which
symptom indicates RA over OA?
Red and swollen joints
More larger joints affected than smaller joints
Symmetrical PIPs were affected
7. Describe how premature birth can contribute to the development of
osteoporosis.
Premature birth only affects muscle development.
, Premature birth can lead to underdeveloped bones, increasing the
risk of osteoporosis.
Premature birth has no effect on bone health.
Premature birth strengthens bone density.
8. What is the primary role of proteoglycans in articular cartilage?
Facilitate joint movement
Resist compression forces
Store calcium
Provide tensile strength
9. Describe how prolonged immobilization can affect joint health and
potentially lead to osteoarthritis.
Prolonged immobilization has no effect on joint health.
Prolonged immobilization only affects muscle strength, not joint
health.
Prolonged immobilization can lead to decreased joint lubrication
and increased stiffness, contributing to the development of
osteoarthritis.
Prolonged immobilization strengthens the joint and prevents
osteoarthritis.
10. Describe the role of osteoprotegerin (OPG) in bone metabolism and how it
might be affected in a young athlete with amenorrhea.
OPG is primarily involved in muscle metabolism rather than bone
health.
