SYSTEM TEST 2026 COMPREHENSIVE TEST
SCRIPT FULL QUESTIONS AND ANSWERS
▶ Medications used to treat cocaine induced chest pain and MI?
Answer:nitroglycerin, aspirin
▶ Medication to avoid in cocaine induced chest pain and MI?
Answer:metoprolol (betablockers are contraindicated in this population
because it further lowers coronary blood flow thereby increasing ischemia)
▶ Medication to treat cocain use disorder? Answer:Antabuse
▶ MOA of antabuse in cocaine use disorder? Answer:increases synaptic
dopamine in the brain reward circuit and act as an agonist treatment
▶ Medication used to treat insomnia in patients with SUD?
Answer:gabapentin
▶ Drug to treat cocaine intoxication with severe agitation?
Answer:lorazepam
▶ Two antipsychotics with FDA approval for severe behavioral issues in
ASD? Answer:Risperidone & aripiprazole
▶ Risperidone for ASD can be used in ages? Answer:5-18
▶ Aripiprazole for ASD can be used in ages? Answer:6-17
▶ What symptoms do the antipsychotics ideally treat in ASD??
Answer:Autism associated irritability, aggression, temper tantrums, self-
injurous behaviors, mood lability
▶ First line intervention for ASD? Answer:ABA (applied behavioral
analysis)
▶ Side effects of risperidone? Answer:weight gain, fatigue, increased
appetite, drooling
, ▶ Alpha-2 agonists used in ASD? Answer:clonidine & guanfacine
▶ Why are alpha-2 agonists used in ASD?? Answer:In patients with ASD
who have symptoms of ADHD
▶ Clonidine in ASD targets? Answer:This alpha 2 agonist hyperactivity and
inattention
▶ Guanfacine in ASD targets? Answer:This alpha2 agonist decreases
autonomic arousal, for patients who have poorly responded to stimulants
▶ Fluvoxemine in ASD targets? Answer:This SSRI targets repetitive
thoughts, repetitive behaviors, and aggression, and inappropriate
language.
▶ mirtazepine use in ASD? Answer:This atypical antidepressant is useful
for sleep & anxiety
▶ OTC used for sleep in ASD? Answer:melatonin
▶ First line for ADD/ADHD? Answer:stimulants (study
guide)/methylphenidate (DynaMed)
▶ MOA of methylphenidate? Answer:norepinephrine and dopamine
reuptake inhibitor (NET & DAT blocker) specifically increasing NE & DA in
the PFC
▶ Which stimulants are "slow release"? Answer:extended release
stimulants, transdermaml methylphenidate, lisdexamphetamine
▶ Selecting a stimulant for each patient should be tailored to:?
Answer:Onset & duration
▶ Stimulants increase dopamine in the...? Answer:prefrontal cortex,
nucleus accumbens, and reward circuitry
▶ Side effects of stimulants for ADHD? Answer:insomnia, dry mouth,
decreased appetite, increased blood pressure, anxiety or nervousness,
headaches, mood swings
SCRIPT FULL QUESTIONS AND ANSWERS
▶ Medications used to treat cocaine induced chest pain and MI?
Answer:nitroglycerin, aspirin
▶ Medication to avoid in cocaine induced chest pain and MI?
Answer:metoprolol (betablockers are contraindicated in this population
because it further lowers coronary blood flow thereby increasing ischemia)
▶ Medication to treat cocain use disorder? Answer:Antabuse
▶ MOA of antabuse in cocaine use disorder? Answer:increases synaptic
dopamine in the brain reward circuit and act as an agonist treatment
▶ Medication used to treat insomnia in patients with SUD?
Answer:gabapentin
▶ Drug to treat cocaine intoxication with severe agitation?
Answer:lorazepam
▶ Two antipsychotics with FDA approval for severe behavioral issues in
ASD? Answer:Risperidone & aripiprazole
▶ Risperidone for ASD can be used in ages? Answer:5-18
▶ Aripiprazole for ASD can be used in ages? Answer:6-17
▶ What symptoms do the antipsychotics ideally treat in ASD??
Answer:Autism associated irritability, aggression, temper tantrums, self-
injurous behaviors, mood lability
▶ First line intervention for ASD? Answer:ABA (applied behavioral
analysis)
▶ Side effects of risperidone? Answer:weight gain, fatigue, increased
appetite, drooling
, ▶ Alpha-2 agonists used in ASD? Answer:clonidine & guanfacine
▶ Why are alpha-2 agonists used in ASD?? Answer:In patients with ASD
who have symptoms of ADHD
▶ Clonidine in ASD targets? Answer:This alpha 2 agonist hyperactivity and
inattention
▶ Guanfacine in ASD targets? Answer:This alpha2 agonist decreases
autonomic arousal, for patients who have poorly responded to stimulants
▶ Fluvoxemine in ASD targets? Answer:This SSRI targets repetitive
thoughts, repetitive behaviors, and aggression, and inappropriate
language.
▶ mirtazepine use in ASD? Answer:This atypical antidepressant is useful
for sleep & anxiety
▶ OTC used for sleep in ASD? Answer:melatonin
▶ First line for ADD/ADHD? Answer:stimulants (study
guide)/methylphenidate (DynaMed)
▶ MOA of methylphenidate? Answer:norepinephrine and dopamine
reuptake inhibitor (NET & DAT blocker) specifically increasing NE & DA in
the PFC
▶ Which stimulants are "slow release"? Answer:extended release
stimulants, transdermaml methylphenidate, lisdexamphetamine
▶ Selecting a stimulant for each patient should be tailored to:?
Answer:Onset & duration
▶ Stimulants increase dopamine in the...? Answer:prefrontal cortex,
nucleus accumbens, and reward circuitry
▶ Side effects of stimulants for ADHD? Answer:insomnia, dry mouth,
decreased appetite, increased blood pressure, anxiety or nervousness,
headaches, mood swings
