CERTIFIED MULTIPLE SCLEROSIS SPECIALIST
EXAM PREP CMSC QUESTIONS AND 100%
CORRECT ANSWERS
\Q\.Relapse Remitting Multiple Sclerosis (RRMS) - ANSWERS✔-Periods of acute worsening of
neurologic function, with some degree of recovery. There is o progression in between. About
85% individuals are dx with RRMS initially
\Q\.How often can remissions occur in RRMS? - ANSWERS✔-Remissions can be months to years
with no new signs of disease activity. Deficits suffered during attacks or exacerbation may totally
resolve or result in ongoing deficits.
\Q\.Secondary Progressive (SPMS) - ANSWERS✔-Following an initial relapse remitting course,
the disease transitions in many people to a steadily progressive form with increased loss of
function. OF the 85% who start with RRMS, more than 50% will develop SPMA within 10 years
and 90% within 25 years.
\Q\.Primary Progressive Multiple Sclerosis (PPMS) - ANSWERS✔-Continuing worsening of
disease from onset, without distinct relapses. Approximately 10% of people are dx with PPMS.
\Q\.Progressive-Relapsing Multiple Sclerosis (PPMS) - ANSWERS✔-Progressive neurologic
decline with occasional acute relapses. About 5% of people appear to have PRMS at diagnosis.
\Q\.Benign MS - ANSWERS✔-Patients who have rare attacks and are minimally disables 20 years
after being diagnose with MS. About 10% of MS patients experience a "benign course" of MS.
, \Q\.Radiologically Isolated Syndrome (RIS) - ANSWERS✔-Radiologically isolated syndrome (RIS)
is another early indicator of demyelination but with no symptoms. RIS is usually detected
incidentally in healthy people who have an MRI that shows typical MS lesions. These people
may remain asymptomatic (have no symptoms), or go on to develop CIS or MS. Therefore, RIS
may represent the earliest indicator of MS before symptoms appear.
\Q\.Clinically Isolated Syndrome (CIS) - ANSWERS✔-A term that describes a first clinical episode
with features suggestive of multiple sclerosis. Usually occurs in young adults and affects optic
nerves, brainstem, or the spinal cord. They usually recover from their presenting episode. It is
often the first manifestation of MS.
\Q\.Pediatric MS - ANSWERS✔-5% of all patients with MS develop the disease before age of 18,
1% before the age of 10 years. Data suggests IFN Beta and glatiramer acetate are safe, effective,
and well tolerated I the pediatric population.
\Q\.10 year outlook for individuals with MS
(How many utilize a cane to ambulate? What percentage require a wheelchair? How man
convert to secondary progressive phase of the disease? - ANSWERS✔-1/2 of patients use a cane
to ambulate
15% require a wheelchair
Approximately 1/2 of patients convert to SPMS
\Q\.Multiple Sclerosis Definition - ANSWERS✔-The most common immune-mediated
inflammatory demyelinating disease of the central nervous system (CNS) - the brain, spinal cord,
and optic nerves- and is a leading cause of disability in young adults. It is thought that the
immune system attacks theCNS.
\Q\.Myelin - ANSWERS✔-Coating that surrounds the nerve fibers
EXAM PREP CMSC QUESTIONS AND 100%
CORRECT ANSWERS
\Q\.Relapse Remitting Multiple Sclerosis (RRMS) - ANSWERS✔-Periods of acute worsening of
neurologic function, with some degree of recovery. There is o progression in between. About
85% individuals are dx with RRMS initially
\Q\.How often can remissions occur in RRMS? - ANSWERS✔-Remissions can be months to years
with no new signs of disease activity. Deficits suffered during attacks or exacerbation may totally
resolve or result in ongoing deficits.
\Q\.Secondary Progressive (SPMS) - ANSWERS✔-Following an initial relapse remitting course,
the disease transitions in many people to a steadily progressive form with increased loss of
function. OF the 85% who start with RRMS, more than 50% will develop SPMA within 10 years
and 90% within 25 years.
\Q\.Primary Progressive Multiple Sclerosis (PPMS) - ANSWERS✔-Continuing worsening of
disease from onset, without distinct relapses. Approximately 10% of people are dx with PPMS.
\Q\.Progressive-Relapsing Multiple Sclerosis (PPMS) - ANSWERS✔-Progressive neurologic
decline with occasional acute relapses. About 5% of people appear to have PRMS at diagnosis.
\Q\.Benign MS - ANSWERS✔-Patients who have rare attacks and are minimally disables 20 years
after being diagnose with MS. About 10% of MS patients experience a "benign course" of MS.
, \Q\.Radiologically Isolated Syndrome (RIS) - ANSWERS✔-Radiologically isolated syndrome (RIS)
is another early indicator of demyelination but with no symptoms. RIS is usually detected
incidentally in healthy people who have an MRI that shows typical MS lesions. These people
may remain asymptomatic (have no symptoms), or go on to develop CIS or MS. Therefore, RIS
may represent the earliest indicator of MS before symptoms appear.
\Q\.Clinically Isolated Syndrome (CIS) - ANSWERS✔-A term that describes a first clinical episode
with features suggestive of multiple sclerosis. Usually occurs in young adults and affects optic
nerves, brainstem, or the spinal cord. They usually recover from their presenting episode. It is
often the first manifestation of MS.
\Q\.Pediatric MS - ANSWERS✔-5% of all patients with MS develop the disease before age of 18,
1% before the age of 10 years. Data suggests IFN Beta and glatiramer acetate are safe, effective,
and well tolerated I the pediatric population.
\Q\.10 year outlook for individuals with MS
(How many utilize a cane to ambulate? What percentage require a wheelchair? How man
convert to secondary progressive phase of the disease? - ANSWERS✔-1/2 of patients use a cane
to ambulate
15% require a wheelchair
Approximately 1/2 of patients convert to SPMS
\Q\.Multiple Sclerosis Definition - ANSWERS✔-The most common immune-mediated
inflammatory demyelinating disease of the central nervous system (CNS) - the brain, spinal cord,
and optic nerves- and is a leading cause of disability in young adults. It is thought that the
immune system attacks theCNS.
\Q\.Myelin - ANSWERS✔-Coating that surrounds the nerve fibers
