NSC 830 Advanced Pharmacology Exam
Questions With Complete Solutions
Narrow |Specturm |- |CORRECT |ANSWER✔✔-Treat |limited |# |of |organisms, |Less |likely |to |disrupt |
normal |flora, |organism |identified.
Broad |Specturm |- |CORRECT |ANSWER✔✔-Treats |multiple |organisms, |more |likely |to |disrupt |
normal |flora, |causative |agent |unknown.
Why |would |you |select |abx? |- |CORRECT |ANSWER✔✔-Is |antimicrobial |therapy |indicated, |make |a
|clinical |diagnosis, |collection |of |specimens |for |a |cx |or |lab |test, |make |microbial |diagnosis, |select
|drug.
Extended |spectrum |- |CORRECT |ANSWER✔✔-treats |multiple |organisms, |more |likely |to |disrupt |
normal |flora, |used |when |causative |organism |is |unknown.
Gram |positive |- |CORRECT |ANSWER✔✔-Purple, |thick |layer
Example |of |gram |positive |- |CORRECT |ANSWER✔✔-Group |A |beta-strep
Strep |PNA
Gram |negative |- |CORRECT |ANSWER✔✔-Red |or |pink, |thin |layer
Example |of |gram |negative |- |CORRECT |ANSWER✔✔-H. |influenza
N. |Gonoccocus
,Atypical |Organism |- |CORRECT |ANSWER✔✔-colorless, |no |layer
Example |of |Atypical |organism |- |CORRECT |ANSWER✔✔-Macrolides- |erythromycins
True |or |False: |Atypical |bacteria |are |resistent |to |becta-lactum |abx |- |CORRECT |ANSWER✔✔-True
Risk |factors |for |Drug |Resistant |Strep |PNA |(DRSP) |- |CORRECT |ANSWER✔✔-Recent |abx |use
Older |>65
Multiple |Comorbidtities |( |COPD, |DM, |HF, |renal |failure)
Daycare |worker
Alcoholism
Immunosuppressed |(including |chronic |steroid |use |>10 |mg/day |long |term).
Treatment |for |Drug |Resistant |Strep |PNA |- |CORRECT |ANSWER✔✔-High |dose |amoxicillin
|3-4g/day
Respiratory |fluoroquinolones: |moxifloxican, |gemifloxican, |levofloxacin. |
Tehlithromycin: |use |limited |due |to |hepatoxicity
Factors |to |determine |when |selecting |an |abx... |- |CORRECT |ANSWER✔✔-Allergy |history |(PCN- |
risk |of |cross |allergy |with |cephalosporins)
Age- |(Renal |function- |neonates |and |elderly)
Pregnancy
Immunocompromised |status
Affordability
Taste |and |convenience
What |are |2 |abx |contraindicated |in |pregnancy? |- |CORRECT |ANSWER✔✔-tetracyclines
, fluoroquinolone
Do |immunocompromised |patients |get |bactericidal |or |baceriostiatic? |- |CORRECT |ANSWER✔✔-
Bactericidals
What |are |bactericidals? |- |CORRECT |ANSWER✔✔-Kills |bacteria
What |are |bacteriostatic? |- |CORRECT |ANSWER✔✔-Restrains |production |of |bacteria. |The |
patient |needs |a |good |immune |system.
Minimum |inhibitory |concentration |(MIC) |- |CORRECT |ANSWER✔✔-Min. |amount |of |abx |used |to |
inhibit |growth |of |bacteria. |Abx |usually |dosed |2-4 |times |MIC
Teaching |the |patient |to |..... |- |CORRECT |ANSWER✔✔-Take |ALL |of |medication
May |need |back |up |birth |control |and |for |7 |days |after. |
Report |signs |of |allergic |reaction |(SOA, |Wheezing, |rash)
General |side |effects |of |abx |- |CORRECT |ANSWER✔✔-Hypersensitivity: |(allergic |reaction-rash, |
itching, |LBP, |wheezing, |SOA).
Diarrhea: |make |sure |to |report |blood, |mucous
Superinfection: |Due |to |disruption |of |normal |flora |(oral |thrush, |yeast |infection)
True |or |False: |Is |extended |care |more |likely |to |cause |diarrhea? |- |CORRECT |ANSWER✔✔-True
Examples |of |Beta-Lactam |Abx? |- |CORRECT |ANSWER✔✔-PCN |& |Cephalosporins
What |do |Beta-Lactam |abx |have |on |them? |- |CORRECT |ANSWER✔✔-A |ring- |that |works |by |
disrupting |the |biosynthesis |of |the |cell |wall.
Questions With Complete Solutions
Narrow |Specturm |- |CORRECT |ANSWER✔✔-Treat |limited |# |of |organisms, |Less |likely |to |disrupt |
normal |flora, |organism |identified.
Broad |Specturm |- |CORRECT |ANSWER✔✔-Treats |multiple |organisms, |more |likely |to |disrupt |
normal |flora, |causative |agent |unknown.
Why |would |you |select |abx? |- |CORRECT |ANSWER✔✔-Is |antimicrobial |therapy |indicated, |make |a
|clinical |diagnosis, |collection |of |specimens |for |a |cx |or |lab |test, |make |microbial |diagnosis, |select
|drug.
Extended |spectrum |- |CORRECT |ANSWER✔✔-treats |multiple |organisms, |more |likely |to |disrupt |
normal |flora, |used |when |causative |organism |is |unknown.
Gram |positive |- |CORRECT |ANSWER✔✔-Purple, |thick |layer
Example |of |gram |positive |- |CORRECT |ANSWER✔✔-Group |A |beta-strep
Strep |PNA
Gram |negative |- |CORRECT |ANSWER✔✔-Red |or |pink, |thin |layer
Example |of |gram |negative |- |CORRECT |ANSWER✔✔-H. |influenza
N. |Gonoccocus
,Atypical |Organism |- |CORRECT |ANSWER✔✔-colorless, |no |layer
Example |of |Atypical |organism |- |CORRECT |ANSWER✔✔-Macrolides- |erythromycins
True |or |False: |Atypical |bacteria |are |resistent |to |becta-lactum |abx |- |CORRECT |ANSWER✔✔-True
Risk |factors |for |Drug |Resistant |Strep |PNA |(DRSP) |- |CORRECT |ANSWER✔✔-Recent |abx |use
Older |>65
Multiple |Comorbidtities |( |COPD, |DM, |HF, |renal |failure)
Daycare |worker
Alcoholism
Immunosuppressed |(including |chronic |steroid |use |>10 |mg/day |long |term).
Treatment |for |Drug |Resistant |Strep |PNA |- |CORRECT |ANSWER✔✔-High |dose |amoxicillin
|3-4g/day
Respiratory |fluoroquinolones: |moxifloxican, |gemifloxican, |levofloxacin. |
Tehlithromycin: |use |limited |due |to |hepatoxicity
Factors |to |determine |when |selecting |an |abx... |- |CORRECT |ANSWER✔✔-Allergy |history |(PCN- |
risk |of |cross |allergy |with |cephalosporins)
Age- |(Renal |function- |neonates |and |elderly)
Pregnancy
Immunocompromised |status
Affordability
Taste |and |convenience
What |are |2 |abx |contraindicated |in |pregnancy? |- |CORRECT |ANSWER✔✔-tetracyclines
, fluoroquinolone
Do |immunocompromised |patients |get |bactericidal |or |baceriostiatic? |- |CORRECT |ANSWER✔✔-
Bactericidals
What |are |bactericidals? |- |CORRECT |ANSWER✔✔-Kills |bacteria
What |are |bacteriostatic? |- |CORRECT |ANSWER✔✔-Restrains |production |of |bacteria. |The |
patient |needs |a |good |immune |system.
Minimum |inhibitory |concentration |(MIC) |- |CORRECT |ANSWER✔✔-Min. |amount |of |abx |used |to |
inhibit |growth |of |bacteria. |Abx |usually |dosed |2-4 |times |MIC
Teaching |the |patient |to |..... |- |CORRECT |ANSWER✔✔-Take |ALL |of |medication
May |need |back |up |birth |control |and |for |7 |days |after. |
Report |signs |of |allergic |reaction |(SOA, |Wheezing, |rash)
General |side |effects |of |abx |- |CORRECT |ANSWER✔✔-Hypersensitivity: |(allergic |reaction-rash, |
itching, |LBP, |wheezing, |SOA).
Diarrhea: |make |sure |to |report |blood, |mucous
Superinfection: |Due |to |disruption |of |normal |flora |(oral |thrush, |yeast |infection)
True |or |False: |Is |extended |care |more |likely |to |cause |diarrhea? |- |CORRECT |ANSWER✔✔-True
Examples |of |Beta-Lactam |Abx? |- |CORRECT |ANSWER✔✔-PCN |& |Cephalosporins
What |do |Beta-Lactam |abx |have |on |them? |- |CORRECT |ANSWER✔✔-A |ring- |that |works |by |
disrupting |the |biosynthesis |of |the |cell |wall.
