Page 1 of 93
MIDTERM EXAM: NR507 / NR-507 (LATEST UPDATE
STUDY BUNDLE WITH COMPLETE
SOLUTIONS) ADVANCED PATHOPHYSIOLOGY |
QUESTIONS & VERIFIED ANSWERS | 100% CORRECT |
GRADE A - CHAMBERLAIN
Hypersensitivity: Type 1 .....ANSWER.....-Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 .....ANSWER.....-Cytotoxic reaction: tissue
specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
,Page 2 of 93
Hypersensitivity 2 .....ANSWER.....-Graves Disease
(hyperthyroidism) -alters function not destroy
-blood transfusions reaction- transfused erythrocytes are
destroyed by agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 .....ANSWER.....-Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE
that was released into the blood or bodily fluids, and the
complex is then deposited in the tissues
Hypersensitivity: Type 3 .....ANSWER.....-rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) .....ANSWER.....Hypersensitivity Type 1
,Page 3 of 93
First responders to innate the immune system
.....ANSWER.....Neutrophils
Allergic contact dermatitis .....ANSWER.....Hypersensitivity Type
IV
Type 2 cytotoxic hypersensitivity mediated by: .....ANSWER.....-
IgG IgM
-macrophages are primary effort cells
-
Serum Sickness .....ANSWER.....type 3 hypersensitivity
Hypersensitivity IV, .....ANSWER.....-is more of a delayed immune
response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune .....ANSWER.....-diseases in which the body makes
antibodies directed against its own tissues
-
, Page 4 of 93
Primary immunodeficiency .....ANSWER.....-Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency .....ANSWER.....-acquired
Common cause of secondary immunodeficiency
.....ANSWER.....Malnutrition
Most patients diagnosed with SLE will have a positive ?
.....ANSWER.....antinuclear antibody (ANA)
SLE (lupus) .....ANSWER.....-Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity?
.....ANSWER.....Glomerulonephritis
MIDTERM EXAM: NR507 / NR-507 (LATEST UPDATE
STUDY BUNDLE WITH COMPLETE
SOLUTIONS) ADVANCED PATHOPHYSIOLOGY |
QUESTIONS & VERIFIED ANSWERS | 100% CORRECT |
GRADE A - CHAMBERLAIN
Hypersensitivity: Type 1 .....ANSWER.....-Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 .....ANSWER.....-Cytotoxic reaction: tissue
specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
,Page 2 of 93
Hypersensitivity 2 .....ANSWER.....-Graves Disease
(hyperthyroidism) -alters function not destroy
-blood transfusions reaction- transfused erythrocytes are
destroyed by agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 .....ANSWER.....-Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE
that was released into the blood or bodily fluids, and the
complex is then deposited in the tissues
Hypersensitivity: Type 3 .....ANSWER.....-rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) .....ANSWER.....Hypersensitivity Type 1
,Page 3 of 93
First responders to innate the immune system
.....ANSWER.....Neutrophils
Allergic contact dermatitis .....ANSWER.....Hypersensitivity Type
IV
Type 2 cytotoxic hypersensitivity mediated by: .....ANSWER.....-
IgG IgM
-macrophages are primary effort cells
-
Serum Sickness .....ANSWER.....type 3 hypersensitivity
Hypersensitivity IV, .....ANSWER.....-is more of a delayed immune
response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune .....ANSWER.....-diseases in which the body makes
antibodies directed against its own tissues
-
, Page 4 of 93
Primary immunodeficiency .....ANSWER.....-Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency .....ANSWER.....-acquired
Common cause of secondary immunodeficiency
.....ANSWER.....Malnutrition
Most patients diagnosed with SLE will have a positive ?
.....ANSWER.....antinuclear antibody (ANA)
SLE (lupus) .....ANSWER.....-Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity?
.....ANSWER.....Glomerulonephritis
