Page 1 of 45
EXAM 1 - 3, MIDTERM & FINAL EXAM: NU641 / NU 641
(LATEST UPDATES STUDY BUNDLE
PACKAGE WITH SOLUTIONS) ADVANCED CLINICAL
PHARMACOLOGY | QUESTIONS AND ANSWERS |
GRADE A | 100% CORRECT (VERIFIED ANSWERS) -
REGIS
Carbamazepine (Tegretol) .....ANSWER.....-also used for mood
stabilizer
-Uses: Epilepsy-partial complex seizures and generalized,
Bipolar disorders, Trigeminal and glossopharyngeal neuralgias
-CBC before & periodically during
-Adverse effects:
-CNS symptoms—nystagmus, ataxia
-Anemia, leukopenia, thrombocytopenia (Black box warning)
,Page 2 of 45
-Birth defects
-Autoinduction (induces its own metabolism) as well as others
-Has anticholinergic effects
insomnia .....ANSWER.....-inability to sleep for 3 successive night
for 4 weeks
-Problems can be initiating or maintaining sleep
-Prevalence increases with age
-Women have insomnia after childbirth
-increased metabolic rate and higher cortisol levels, ruminate,
worry, intrusive thoughts
-Circadian factors influence sleep
insomnia treatment .....ANSWER.....-Ramelteon- does not increase
risk for patients engaging in activities while somnolent
-Non-drug therapy-sleep hygiene
,Page 3 of 45
-Sleep diary
-Rule out psychophysiologic causes such as depression, anxiety,
mood disorders, PTS, obstructive sleep apnea, medication side
effects
insomnia treatment pharmacologic .....ANSWER.....-Not
recommended for elderly
-Benzodiazepines
-Benzodiazepine-like drugs
-Antidepressants SSRI (paxil, trazadone, remeron and the
atypical can be a little sedating)
-Antihistamines (diphenhydramine) tylenol/advil pm
-Valerian root
rules for sleep fitness .....ANSWER.....-Regular times
-Don't over do it
, Page 4 of 45
-Sound proof the room
-Cool temperature
-Exercise early in the day
-No naps
-Decrease fluids at night
-Hide the clock
epilepsy .....ANSWER.....Group of disorders characterized by
excessive neuron stimulation within the central nervous system
anticonvulsants .....ANSWER.....-know pts medication regimen;
many drug-drug interactions with anticonvulsants
-anticonvulsants commonly carry narrow therapeutic indexes, i.e.
their doses and blood levels work in a narrow range balancing
between being ineffective and toxic.
-NPs do not prescribe them
EXAM 1 - 3, MIDTERM & FINAL EXAM: NU641 / NU 641
(LATEST UPDATES STUDY BUNDLE
PACKAGE WITH SOLUTIONS) ADVANCED CLINICAL
PHARMACOLOGY | QUESTIONS AND ANSWERS |
GRADE A | 100% CORRECT (VERIFIED ANSWERS) -
REGIS
Carbamazepine (Tegretol) .....ANSWER.....-also used for mood
stabilizer
-Uses: Epilepsy-partial complex seizures and generalized,
Bipolar disorders, Trigeminal and glossopharyngeal neuralgias
-CBC before & periodically during
-Adverse effects:
-CNS symptoms—nystagmus, ataxia
-Anemia, leukopenia, thrombocytopenia (Black box warning)
,Page 2 of 45
-Birth defects
-Autoinduction (induces its own metabolism) as well as others
-Has anticholinergic effects
insomnia .....ANSWER.....-inability to sleep for 3 successive night
for 4 weeks
-Problems can be initiating or maintaining sleep
-Prevalence increases with age
-Women have insomnia after childbirth
-increased metabolic rate and higher cortisol levels, ruminate,
worry, intrusive thoughts
-Circadian factors influence sleep
insomnia treatment .....ANSWER.....-Ramelteon- does not increase
risk for patients engaging in activities while somnolent
-Non-drug therapy-sleep hygiene
,Page 3 of 45
-Sleep diary
-Rule out psychophysiologic causes such as depression, anxiety,
mood disorders, PTS, obstructive sleep apnea, medication side
effects
insomnia treatment pharmacologic .....ANSWER.....-Not
recommended for elderly
-Benzodiazepines
-Benzodiazepine-like drugs
-Antidepressants SSRI (paxil, trazadone, remeron and the
atypical can be a little sedating)
-Antihistamines (diphenhydramine) tylenol/advil pm
-Valerian root
rules for sleep fitness .....ANSWER.....-Regular times
-Don't over do it
, Page 4 of 45
-Sound proof the room
-Cool temperature
-Exercise early in the day
-No naps
-Decrease fluids at night
-Hide the clock
epilepsy .....ANSWER.....Group of disorders characterized by
excessive neuron stimulation within the central nervous system
anticonvulsants .....ANSWER.....-know pts medication regimen;
many drug-drug interactions with anticonvulsants
-anticonvulsants commonly carry narrow therapeutic indexes, i.e.
their doses and blood levels work in a narrow range balancing
between being ineffective and toxic.
-NPs do not prescribe them
