OCN Study Guide Questions with Correct
Answers
What does FFP do? Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem of
unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? Leukemia, specifically APL
Signs/Symptoms of DIC bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC Delivery (of baby)
Infection
Cancer
,How does Heparin help DIC? Interferes with thrombin production. Maintain PTT at 1-2
times the normal level (18-28 seconds)
S/S of septic shock Fever
Tachycardia
Hypotension
Most common cause of sepsis Gram (-) bacteria
DIC Accelerated activation of the coagulation cascade. Clots form in random places
leaving the body open to bleeding without protection
Platelet count, Fibrinogen level, D Dimer, FDP Titer Tests to diagnose DIC
How to treat DIC Treat underlying cause
,What does FFP do? Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem of
unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? Leukemia, specifically APL
Signs/Symptoms of DIC bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC Delivery (of baby)
Infection
Cancer
How does Heparin help DIC? Interferes with thrombin production. Maintain PTT at 1-2
times the normal level (18-28 seconds)
, S/S of septic shock Fever
Tachycardia
Hypotension
Most common cause of sepsis Gram (-) bacteria
Granulocytopenia failure of the bone marrow to make enough
white blood cells (neutrophils)
Highest risk factor for sepsis Prolonged granulocytopenia (less than 500/mm3)
What cancer commonly produces TLS? High grade lymphoma
Define Tumor Lysis Syndrome (TLS) metabolic imbalance that occurs with rapid tumor
kill
Lab results indicating DIC Increased D Dimer
Answers
What does FFP do? Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem of
unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? Leukemia, specifically APL
Signs/Symptoms of DIC bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC Delivery (of baby)
Infection
Cancer
,How does Heparin help DIC? Interferes with thrombin production. Maintain PTT at 1-2
times the normal level (18-28 seconds)
S/S of septic shock Fever
Tachycardia
Hypotension
Most common cause of sepsis Gram (-) bacteria
DIC Accelerated activation of the coagulation cascade. Clots form in random places
leaving the body open to bleeding without protection
Platelet count, Fibrinogen level, D Dimer, FDP Titer Tests to diagnose DIC
How to treat DIC Treat underlying cause
,What does FFP do? Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem of
unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? Leukemia, specifically APL
Signs/Symptoms of DIC bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC Delivery (of baby)
Infection
Cancer
How does Heparin help DIC? Interferes with thrombin production. Maintain PTT at 1-2
times the normal level (18-28 seconds)
, S/S of septic shock Fever
Tachycardia
Hypotension
Most common cause of sepsis Gram (-) bacteria
Granulocytopenia failure of the bone marrow to make enough
white blood cells (neutrophils)
Highest risk factor for sepsis Prolonged granulocytopenia (less than 500/mm3)
What cancer commonly produces TLS? High grade lymphoma
Define Tumor Lysis Syndrome (TLS) metabolic imbalance that occurs with rapid tumor
kill
Lab results indicating DIC Increased D Dimer
