OCR A-Level Biology Liver Summary

Main Metabolic Waste products :

CO2 ,
Urea , bile
pigments
Hepatic Artery Supplies blood to the liver
:




Hepatic Vein :
Returns blood to the heart

Hepatic Portal Vein Carries blood
:
from the intestines to the liver s full of digestive product
Hepatocytes liver cells
large nucleus ,
prominent golgi body many mitochondria
:

,




structure of the liver :

· Sinusoids Channels blood from the hepatic and hepatic
where
artery
:




portal vein mix <
bordered by sinusoids
↳ O2 delivered to the
is
hepatocytes
·hupffer Ceus Liver within
Macrophages hepatocytes
:




Bile Canaliculi ductules
Hepatocytes Secrete bile into the bile
:




functions of the Liver:

Builds up breaks down
Carbohydrate Metabolism or
glycogen
:




Deamination of excess anino acids Amino Acids
·
:




Amino combines ~3 CO2
group




&
produce
-
With CO2 to urea
1 0
,


The rest of the molecule




WHO-I onetrone
ornithine
, urea
can be used as a -




substrate
respiratory

Detoxification of :

other metabolic substrates

Catalase enzyme converts H202 to H20 and On
· ethanal s Ethanoate
Alcohol
dehydrogenase convers ethanol



Cirrhosis liver tissue is
replaced by tissue due to alcohol
scar
susually
:


use

↳ die and disrupted
Hepatocytes structure is