Inhoud
Epithelen......................................................................................................5
Bedekkende epitelen................................................................................6
Cytoskelet: keratine...............................................................................6
Epitheelcel.............................................................................................7
Celpolariteit: apicaal..............................................................................7
Celpolariteit: lateraal.............................................................................7
Intercellulaire verbindingen...................................................................8
Celpolariteit: basale...............................................................................8
Bedekkende epithelen..............................................................................8
Overgangsepitheel..................................................................................11
klierepitheel...............................................................................................11
Ontstaan Exocriene klieren....................................................................12
Ontstaan endocriene klieren...................................................................12
Exocriene klieren indeling.......................................................................12
Indeling naargelang de algemene morfologie.....................................13
Vorm van een kliercel groep:...............................................................13
Aantal afvoergangen...........................................................................13
Inleiding naargelang het geproduceerde secreet................................14
Indeling naargelang de secretiewijze...................................................15
Apocriene secretiewijze.......................................................................15
Endocriene klieren..................................................................................16
Myo- epitheel.......................................................................................16
Bindweefsels..............................................................................................16
Functie....................................................................................................16
Embryologie............................................................................................17
Matrix...................................................................................................18
Grondsubstantie (proteogycanen).......................................................18
Bindweefselvezels...................................................................................19
Tropocollageen.....................................................................................19
Reticulaire vezels.................................................................................20
Weefselvloeistof...................................................................................20
, Bindweefsel ss........................................................................................21
Macrofagen..........................................................................................22
Bindweefsel met speciale eigenschappen..............................................22
Kraakbeenmatrix.................................................................................23
Kraakbeencellen..................................................................................24
Terminologie........................................................................................24
Territorizale matrix (= celhof)..............................................................24
Interterritoriale matrix.........................................................................25
Histogenese.........................................................................................25
Groei....................................................................................................26
Hyalien kraakbeen...............................................................................26
Elastisch kraakbeen.............................................................................26
Vezelig of fibreus kraakbeen................................................................26
Tussenwervelschijven..........................................................................27
Botten........................................................................................................27
Delen van lange pijpbenen.....................................................................27
Diafyse.................................................................................................27
Epifyse.................................................................................................27
Epifysaire groeischijf (ALLEEN tijdens groei)........................................27
Periost (beenvlies)...............................................................................27
Endost ( endosteum)...........................................................................28
Bot of been..........................................................................................28
Functies...............................................................................................28
Botmatrix................................................................................................28
Anorganische zouten:..........................................................................29
Organische matrix:..............................................................................29
Hydroxy – apatiet.................................................................................29
Botcel......................................................................................................29
Osteoblasten........................................................................................30
Osteoclasten........................................................................................30
Soorten botweefsel.................................................................................30
Macroscopisch.....................................................................................30
Micropscopisch....................................................................................31
, Compact lamelair bot..........................................................................31
Systeem van Havers...............................................................................31
Spongieus lamellair bot..........................................................................32
Plexiform of primair bot..........................................................................32
Histogenese: botvorming.....................................................................33
Diktegroei van lange pijpbeenderen.......................................................33
Desmale botvorming............................................................................33
Enchondrale botvorming......................................................................33
Chondrale botvorming.........................................................................34
Gewrichten..............................................................................................36
Diartrose..............................................................................................36
Spierweefsel...............................................................................................36
Skeletspier.................................................................................................37
Actine...................................................................................................37
Myosine................................................................................................37
Myofibrillen..........................................................................................38
Dwarsgestreepte spierweefsel: Controle van de contractie.................39
Skeletspierweefsel: de opbouw van skeletspiercel.................................39
Excitatie- contractie koppeling................................................................40
Skeletspierceltypen.................................................................................40
Regenatie.............................................................................................41
Organisatie van skeletspier.................................................................41
Hartspierweefsel – hartspiercel..................................................................41
Opbouw:..................................................................................................41
Regenaratie hartspiercellen.................................................................42
Glad spierweefsel.......................................................................................43
Opbouw...................................................................................................43
Organisatie van actine en myosine in de gladde spiercel.......................43
Controle van contractie van gladspierweefsel........................................44
Contractie van de gladde spiercel...........................................................44
Actine en myosinebundels in het cytoplasma.........................................45
Intracellulaire calciumstijging.................................................................45
Hoe geraken de spieren geactiveerd?.....................................................45
, Single unit gladde spieren...................................................................46
Multi unit gladde spieren.....................................................................46
Histogenese en groei.............................................................................46
Regeneratie.............................................................................................46
Zenuwweefsel............................................................................................46
Morfologisch........................................................................................46
Functioneel..........................................................................................47
Histogenese.........................................................................................47
Opbouw zenuwcellen...........................................................................47
Functionele categorieën......................................................................47
Neuronen................................................................................................48
Indeling van neuronen.........................................................................48
Multipolair neuron................................................................................48
Cellichaam..............................................................................................49
Dendrieten..............................................................................................49
Axon........................................................................................................50
Axonaal transportsysteem...................................................................51
Synapsen................................................................................................51
Chemische synapsen...........................................................................52
Presynaptische verdikking...................................................................53
Synaptische spleet...............................................................................53
Postsynaptische component................................................................53
Prikkelgeleiding en prikkeloverdracht.....................................................54
Bij ongemyeliniseerde axonen............................................................54
Bij gemyeliniseerde axon.....................................................................54
Indeling zenuwvezels..............................................................................55
Myelinisatie.............................................................................................55
Cellen van Schwann: in PZS...................................................................56
Satallietcellen.........................................................................................57
Steuncellen van het centraal zenuwstelsel.............................................57
Microgliacellen........................................................................................57
Astrocyten...............................................................................................58
Oligodendrocyten....................................................................................58
Epithelen......................................................................................................5
Bedekkende epitelen................................................................................6
Cytoskelet: keratine...............................................................................6
Epitheelcel.............................................................................................7
Celpolariteit: apicaal..............................................................................7
Celpolariteit: lateraal.............................................................................7
Intercellulaire verbindingen...................................................................8
Celpolariteit: basale...............................................................................8
Bedekkende epithelen..............................................................................8
Overgangsepitheel..................................................................................11
klierepitheel...............................................................................................11
Ontstaan Exocriene klieren....................................................................12
Ontstaan endocriene klieren...................................................................12
Exocriene klieren indeling.......................................................................12
Indeling naargelang de algemene morfologie.....................................13
Vorm van een kliercel groep:...............................................................13
Aantal afvoergangen...........................................................................13
Inleiding naargelang het geproduceerde secreet................................14
Indeling naargelang de secretiewijze...................................................15
Apocriene secretiewijze.......................................................................15
Endocriene klieren..................................................................................16
Myo- epitheel.......................................................................................16
Bindweefsels..............................................................................................16
Functie....................................................................................................16
Embryologie............................................................................................17
Matrix...................................................................................................18
Grondsubstantie (proteogycanen).......................................................18
Bindweefselvezels...................................................................................19
Tropocollageen.....................................................................................19
Reticulaire vezels.................................................................................20
Weefselvloeistof...................................................................................20
, Bindweefsel ss........................................................................................21
Macrofagen..........................................................................................22
Bindweefsel met speciale eigenschappen..............................................22
Kraakbeenmatrix.................................................................................23
Kraakbeencellen..................................................................................24
Terminologie........................................................................................24
Territorizale matrix (= celhof)..............................................................24
Interterritoriale matrix.........................................................................25
Histogenese.........................................................................................25
Groei....................................................................................................26
Hyalien kraakbeen...............................................................................26
Elastisch kraakbeen.............................................................................26
Vezelig of fibreus kraakbeen................................................................26
Tussenwervelschijven..........................................................................27
Botten........................................................................................................27
Delen van lange pijpbenen.....................................................................27
Diafyse.................................................................................................27
Epifyse.................................................................................................27
Epifysaire groeischijf (ALLEEN tijdens groei)........................................27
Periost (beenvlies)...............................................................................27
Endost ( endosteum)...........................................................................28
Bot of been..........................................................................................28
Functies...............................................................................................28
Botmatrix................................................................................................28
Anorganische zouten:..........................................................................29
Organische matrix:..............................................................................29
Hydroxy – apatiet.................................................................................29
Botcel......................................................................................................29
Osteoblasten........................................................................................30
Osteoclasten........................................................................................30
Soorten botweefsel.................................................................................30
Macroscopisch.....................................................................................30
Micropscopisch....................................................................................31
, Compact lamelair bot..........................................................................31
Systeem van Havers...............................................................................31
Spongieus lamellair bot..........................................................................32
Plexiform of primair bot..........................................................................32
Histogenese: botvorming.....................................................................33
Diktegroei van lange pijpbeenderen.......................................................33
Desmale botvorming............................................................................33
Enchondrale botvorming......................................................................33
Chondrale botvorming.........................................................................34
Gewrichten..............................................................................................36
Diartrose..............................................................................................36
Spierweefsel...............................................................................................36
Skeletspier.................................................................................................37
Actine...................................................................................................37
Myosine................................................................................................37
Myofibrillen..........................................................................................38
Dwarsgestreepte spierweefsel: Controle van de contractie.................39
Skeletspierweefsel: de opbouw van skeletspiercel.................................39
Excitatie- contractie koppeling................................................................40
Skeletspierceltypen.................................................................................40
Regenatie.............................................................................................41
Organisatie van skeletspier.................................................................41
Hartspierweefsel – hartspiercel..................................................................41
Opbouw:..................................................................................................41
Regenaratie hartspiercellen.................................................................42
Glad spierweefsel.......................................................................................43
Opbouw...................................................................................................43
Organisatie van actine en myosine in de gladde spiercel.......................43
Controle van contractie van gladspierweefsel........................................44
Contractie van de gladde spiercel...........................................................44
Actine en myosinebundels in het cytoplasma.........................................45
Intracellulaire calciumstijging.................................................................45
Hoe geraken de spieren geactiveerd?.....................................................45
, Single unit gladde spieren...................................................................46
Multi unit gladde spieren.....................................................................46
Histogenese en groei.............................................................................46
Regeneratie.............................................................................................46
Zenuwweefsel............................................................................................46
Morfologisch........................................................................................46
Functioneel..........................................................................................47
Histogenese.........................................................................................47
Opbouw zenuwcellen...........................................................................47
Functionele categorieën......................................................................47
Neuronen................................................................................................48
Indeling van neuronen.........................................................................48
Multipolair neuron................................................................................48
Cellichaam..............................................................................................49
Dendrieten..............................................................................................49
Axon........................................................................................................50
Axonaal transportsysteem...................................................................51
Synapsen................................................................................................51
Chemische synapsen...........................................................................52
Presynaptische verdikking...................................................................53
Synaptische spleet...............................................................................53
Postsynaptische component................................................................53
Prikkelgeleiding en prikkeloverdracht.....................................................54
Bij ongemyeliniseerde axonen............................................................54
Bij gemyeliniseerde axon.....................................................................54
Indeling zenuwvezels..............................................................................55
Myelinisatie.............................................................................................55
Cellen van Schwann: in PZS...................................................................56
Satallietcellen.........................................................................................57
Steuncellen van het centraal zenuwstelsel.............................................57
Microgliacellen........................................................................................57
Astrocyten...............................................................................................58
Oligodendrocyten....................................................................................58
