The nurse is providing medication instructions to an older client who is taking digoxin daily. The nurse explains to the client that decreased lean body mass and decreased glomerular filtration rate, which are age-related body changes, could place the client at risk for which complication with medication therapy?

 1.	Decreased absorption of digoxin

 2.	Increased risk for digoxin toxicity

 3.	Decreased therapeutic effect of digoxin

 4.	Increased risk for side effects related to digoxin





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