NBME Pathology

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NBME PATHOLOGY EXAM WITH LATEST VERIFIED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+ Apoptosis: - ANS-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptot...

Terms in this set (223) Apoptosis: Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. **Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptotic bodies which are phagocytosed. DNA laddering is a sensitive indicato...