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NUR 641E ADVANCED PATHO PHARM DISCUSSION QUESTIONS WITH ANSWERS
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---21abril 20212020/2021
- NUR 641E ADVANCED PATHO PHARM DISCUSSION QUESTIONS WITH ANSWERS 
Discussion question 1/1 
Find an article on a genetic disorder and summarize in two or three paragraphs the genetic 
component causing the disorder and any multifactorial inheritance components that may 
contribute to the disorder. Discuss the usual age of disease onset and if the sex-specific 
threshold model fits the disorder. What education could you present to high-risk patients to 
reduce the risk of disease onset if a multifa...
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Resumen
NUR 641E MID TERM EXAM STUDY GUIDE
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---7abril 20212020/2021
- NUR 641E MID TERM EXAM STUDY GUIDE 
Understand what a prodrug is, and activation/inactivation by liver enzymes, and 
how it differs from active drugs. 
The liver is the principal site of drug metabolism. Although metabolism typically inactivates 
drugs, some drug metabolites are pharmacologically active—sometimes even more so than the 
parent compound. An inactive or weakly active substance that has an active metabolite is called a 
prodrug, especially if designed to deliver the active moiety ...
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