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Examen
Bmb 401 Exam 3 - Msu With 100% Verified Solutions 2023
TCA cycle - Step 1, Oxidative Decarboxylation 
Oxaloacetate + Acetyl CoA + H2O -> Citrate + CoA 
Enzyme: Citrate synthase 
Driven by CoA hydrolysis 
 
 
 
High Citrate Levels Indicate 
well fed state 
1. intermediate in TCA cycle (mitochondria) 
2. activator of fatty acid synthesis (cytoplasm) 
3. precursor of cytoplasmic acetyl CoA (cytoplasm) 
4. inhibitor of PFK1 (cytoplasm) 
 
 
 
Regulation of Citrate Synthase 
Major point of regulation 
Negative - ATP, NADH, Succinyl CoA 
 
 
 
TCA cycl...
Examen
BMB 401 MSU (FOLEY) Exam 1 (Questions and answers) LATEST UPDATE
PopularPattern of separation of charge in electronegativity - ️️The greater the difference 
between the electronegativities of two bonded atoms, the greater the separation of 
charge will be in the bond 
What determines the strength and length of a covalent bond - ️️More shared 
electron pairs increases bond energy and shortens the length between atoms 
Importance of Biochemical Reactions - ️️-Help establish and maintain a stable 
optimal internal environment to preserve life 
-Maintain Hom...
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Bmb 401 Exam Package Deal Rated 100 % Correct
Bmb 401 Exam Package Deal Rated 100 % Correct