NU 545
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NU 545 UNIT 3 9/21 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ 
 
TRH --> TSH --> TH 
Thyroxine - T4 & Triiodothyronine- T3 
 
Lipid soluble; Negative feedback loop 
 
-Essential for normal growth and neurologic development in the fetus and infant 
-Affects metabolic, neurologic, CV and respiratory functioning 
-Required for the metabolism and function of blood cells, normal muscle functioning, and the integrity of skin, nails, and hair 
-Body heat production 
-Insulin an...
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NU 545 PATHOPHYSIOLOGY UNIT 5, RESPIRATORY AND RENAL EXAM QUESTIONS AND ANSWERS WIT COMPLETE SOLUTIONS VERIFIED 
 
Alveoli 
Alveoli: Primary gas exchange units (cont.) 
• Oxygen enters the blood, and carbon dioxide (CO2) is 
removed. 
• Pores of Kohn 
• Epithelial cells 
-Type I alveolar cells (Alveolar structure) 
-Type II alveolar cells (Surfactant production: Prevents lung collapse) 
• Contain alveolar macrophages: Ingest foreign material, 
and remove it through the lymphatic system. ...
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STUDY GUIDE UNIT 1 NU 545 EXAM QUESTIONS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE 
What is metabolic absorption? 
The process of moving nutreints from the intestines into the blood stream. 
What uses oxygen to remove hyrdogen atoms in an oxidative reaction? 
Peroxiomes 
During cell injury what is released that is capable of cellular autodigestion? 
digestive enzymes from lysosomes 
Cellular Injury Chpt. 2 Power Point 
A nurse knows that free radicals may be produced by 
metabolism of exoge...
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NU 545 UNIT 7 TEST STUDY QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ 
In somatic cell gene therapy, what type of vector is most commonly used to alter a specific set of an individual's somatic cells? 
a. 
Virus 
b. 
Bacteria 
c. 
RNA polymerase 
d. 
Recombinant DNA 
ANS: A 
In somatic cell gene therapy, a vector is used to carry a normal copy of the mutated gene into the individual's cells. These vectors are usually viruses, such as retroviruses, lentiviruses, or adenoviruses,...
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NU545 CHAPTER 11 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED. 
Dr. Hans Selye: Known for 
- Worked to discover a new sex hormone. 
- Injected ovarian extracts into rats 
Dr. Hans Selye: Witnessed 
1. Witnessed: 
- Enlargement of the adrenal cortex 
- Thymic atrophy 
- Development of bleeding ulcers in the stomach and duodenal lining 
2. Witnessed these changes with many agents and called these stimuli stressors. 
general adaptation syndrome (GAS). 
Nonspecific response to noxious...
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NU545 CHAPTER 8 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED 
Adaptive immunity: Characteristics 
- Works together with inflammation. 
- Recognizes foreign or "nonself" substances (ex. Antigens) 
- Provides long-term protection. 
- Is slower than innate but more specific. 
- Has memory. 
Example of antigens 
- Pathogens 
- Noninfectious environmental agents 
- Drugs 
- Vaccines 
- Transfusions 
- Transplants 
Adaptive immunity: End products of adaptive immunity 
- Lymphocyte...
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UNIT 1: NU 545, PATHOPHYSIOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED GRADED A++ 
 
InTRAcellular 
within the cell 
InTERcellular 
between cells 
ADsorb 
Adhesion of atoms, ions, or molecules from a gas, liquid, or dissolved solid to a surface 
ABsorb 
Fluid is dissolved by or permeates liquid 
What is metabolic ABsorption? 
Cells taking in and using nutrients and other substances from their surroundings 
Kidney tubules function 
Reabsorb fluids, synthesize PRO 
Intestinal ...
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NU545 CHAPTER 3 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE 
Total Body Water (TBW): Definition 
The sum of fluids within all compartments constitutes the TBW 
What are the 5 types of fluid that make up the TBW? 
1. Intracellular fluid 
2. Extracellular fluid 
3. Interstitial fluid 
4. Intravascular fluid 
5. Transcellular fluids 
Intracellular fluid (ICF): Definition 
Inside the cell, 2/3 of body water 
Extracellular fluid (ECF): Definition 
Outside the cell, 1/3 of body wa...
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NU545 CHAPTER 9 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE 
 
Allergy: 
Is an exaggerated response against 
an environmental antigen. 
Autoimmunity: 
Is a misdirected response against the host's own cells. 
Alloimmunity: 
Is directed against beneficial foreign tissues (e.g., transfusions, transplants) 
Hypersensitivity reactions: 
An altered immunologic response to an antigen that results in disease or damage to the host. 
Sensitization: 
Adequate amount of antibodies or...
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UNIT 3 STUDY GUIDE FOR NU 545 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED. 
 
STIs 
Sexually transmitted infections affecting reproductive health. 
Syphilis stages 
Different phases of syphilis infection progression. 
Cervical cancer causes 
Primarily caused by HPV infection. 
PCOS 
Polycystic ovary syndrome causing hormonal imbalance. 
Primary amenorrhea 
Absence of menstruation by age 15. 
Secondary amenorrhea 
Menstrual cycle cessation after previously regular periods. 
Signs ...
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NU 545 - UNIT 5 PRACTICE QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED 
Which statement is true regarding the pulmonary system? 
The larynx connects the upper and lower airways 
Which statement is true regarding the lower airways? 
The right and left main bronchi enter the lungs at the hila. 
What process describes the exchange of carbon dioxide (CO2) for oxygen? 
Respiration 
Which receptor monitors the pH, partial pressure of CO2 (PaCO2), and the partial pressure of oxygen (PaO2) in ...
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NU 545 CHAPTER 8 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE 
 
immunogenic 
most antigens are ____ and elicit an immune response 
antigen 
a molecule found on the outer surfaces of cells that the immune system recognizes as either part of the body or an outside invader; can react with antibodies or receptors on B and T cells 
paratope 
the antigen-binding site on the antibody or lymphocyte receptor 
adaptive immunity 
the ability to recognize and remember foreign ...
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NU 545 CH 9 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE 
 
Hypersensitivity 
Altered immunologic response to an antigen that results in disease or damage to the host 
allergy 
Deleterious effects of hypersensitivity to environmental antigens 
Autoimmunity 
Disturbance in the immunologic tolerance of self-antigens 
Alloimmunity 
Immune reaction to tissues of another individual 
immunologic homeostasis 
steady state of tolerance to self-antigens or lack of immune reaction agai...
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NU 545 CHAPTER 10 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ 
 
communicability 
ability of a pathogen to spread from person to person 
immunogenicity 
ability of a pathogen to induce an immune response 
infectivity 
ability of the pathogen to invade and multiply in the host 
mechanism of action 
how a pathogen microorganism damages tissues 
pathogenicity 
ability of pathogen to cause a disease 
portal of entry 
route pathogen takes to enter a new reservoir or host 
toxigenici...
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NU 545 UNIT 2 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED. 
 
1. What nerves are capable of regeneration? 
PNS(peripheral nervous system) axons readily regenerate by a process called axonal reaction 
Brain portion responsible for keeping you awake 
The Reticular Activating System (RAS) is a bundle of nerves that sits in your brainstem. And its job is to regulate behavior, arousal, consciousness and motivation. 
Brain portion responsible for controlling thought 
Your prefrontal co...
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NU545 CHAPTER 3 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE 
extracellular fluid 
interstitial fluid, plasma, intravascular fluid, CSF, sweat, urine, etc. 
store less fat, higher metabolic rates, and greater evaporative loss 
why are infants more susceptible to significant total body water loss 
renal 
what mechanisms are not mature enough that regulate fluid and electrolyte conservation; leads to dehydration 
adipose cells 
individuals with more body fat have pro...
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NU 545 CH 15 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE 
 
CNS and PNS 
two divisions of the nervous sytem 
brain and spinal cord 
what makes up the central nervous system 
cranial and spinal nerves 
what makes up the peripheral nervous system 
voluntary 
control of skeletal muscle in the somatic nervous system is ____ 
involuntary 
control of motor and sensory pathways in the autonomic nervous system is ____ 
myelin sheath 
formed around selected axons to create...
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NU 545- UNIT 4 STUDY GUIDE EXAM QUESTIONS WITH COMPLETE SOLUTIONS GRADED A++ 
Infectious Mononucleosis p. 966 
A benign, acute, self-limiting lymphoproliferative clinical syndrome characterized by acute viral infection of B lymphocytes (B cells). Associated with several tumors, most commonly specific lymphomas and nasopharyngeal carcinoma. Most common cause- EBV. 
Major manifestations of EBV induced IM: Pharyngitis, lymphadenopathy, Fever. 
Other viral causes for IM: CMV, adenovirus, HIV, Hep A,...
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NU 545 UNIT 7 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED 
 
Describe the specific chromosomal abnormality responsible for Down Syndrome 
The most well known aneuploidy (those that do not contain a multiple of 23 chromosomes) in an autosome is trisomy of the 21st chromosome. J. Langdon Down 1st described the the disease in 1866. Down syndrome is seen in 1 in 800 births. IQ's between 25 and 70. Facial features: low nasal bridge, epicentral folds, protruding tongue, and flat low...
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NU 545 CH 7 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ 
Cathelicidins 
Family of antimicrobial peptides that in humans has one member. 
Defensins 
antimicrobial peptides that inhibit microbial growth 
Mannose-binding lectin (MBL) 
soluble acute-phase protein in the blood that binds to mannose residues on pathogen surfaces and, when bound, activates the complement system by the lectin pathway 
Resistin-like molecule beta 
Found in intestinal goblet cells, where it appears to pr...
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