AANP Adult gerontology
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AANP Adult gerontology 21
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Biguanindes - ANSWER Metformin (Glucophage) decreases gluconeogenesis, 
increases glycolysis and peripheral glucose uptake (increases insulin sensitivity 
 
 Sulfonylureas - ANSWER First generation: Tolbutamide (oranase), 
chlorpropamide (diabinase), second generation: Glyburide (micronase, diabeta), 
glipizide (glucotrol), glimeprode (amaryl); lowers blood sugar by stimulating the 
release of insulin by the beta cells of the pancreas + causes tissues to take up and 
store glucose mor...
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AANP Adult GeroNtoloGy•AANP Adult GeroNtoloGy
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Biguanindes - ANSWER Metformin (Glucophage) decreases gluconeogenesis, 
increases glycolysis and peripheral glucose uptake (increases insulin sensitivity 
 
 Sulfonylureas - ANSWER First generation: Tolbutamide (oranase), 
chlorpropamide (diabinase), second generation: Glyburide (micronase, diabeta), 
glipizide (glucotrol), glimeprode (amaryl); lowers blood sugar by stimulating the 
release of insulin by the beta cells of the pancreas + causes tissues to take up and 
store glucose mor...