Advanced Pharmacology Final Exam Review
Questions And Answers 2025
Why .are .nitrate-free .periods .every .24 .hours .necessary .for .the .patient .on .nitroglycerin .therapy? .-
.(correct .answer) .-To .inhibit .the .development .of .tolerance
What .does .a .low .level .of .thyroid-stimulating .hormone .indicate? .- .(correct .answer) .-Hyperthroidism
What .would .be .the .best .option .to .treat .a .newly .diagnosed .patient .with .a .low .TSH .level .with? .-
.(correct .answer) .-Propanolol .(Inderal)
Spironoaldactone .(Aldactone) .has .what .mechanism .of .action .(MOA)? .- .(correct .answer) .-Aldosterone
.antagonist
Heparin .exerts .its .therapeutic .action .by .what? .- .(correct .answer) .-Upregulating .the .activity .of .one .of
.the .body's .natural .anticoagulant .molecules, .antithrombin .III
What .physiologic .action .happens .when .the .offending .drug .is .administered .during .an .anaphylactic
.reaction. .- .(correct .answer) .-Mast .cells .liberate .large .doses .of .histamine.
What .are .two .systemic .psoriasis .medications? .- .(correct .answer) .-Photo-therapy .and .topical
.corticosteroids
What .is .the .first .choice .of .drug .therapy .for .the .majority .of .patients .with .uncomplicated .stage .I
.hypertension? .- .(correct .answer) .-Thiazide .diuretics
What .is .the .effect .of .cardiac .glycosides? .- .(correct .answer) .-Digitalis .glycosides .have .a .negative
.chronotropic .effect .on .the .cardiac .muscle .cells.
Amenorrhea .is .the .most .common .side .effect .of .which .birth .control .medication? .- .(correct .answer) .-
Medroxyprogesterone .(Depo-Provera)
What .is .an .anti-hypertensive .agent .which .competes .with .epinephrine .for .available .beta-receptor
.sites? .- .(correct .answer) .-Atenolol .(Tenormin)
, What .type .of .action .does .nitrates .have .on .the .body? .- .(correct .answer) .-Reduction .in .systemic
.venous .tone.
What .is .the .recommended .level .of .low-density .lipoprotein .cholesterol .(LDL) .for .patients .with .known
.coronary .artery .disease? .- .(correct .answer) .-100mg/dl .or .less.
What .is .the .MOA .of .group .IV .anti-dysrhythmia .drugs? .- .(correct .answer) .-Depressing .phase .4
.depolarization .and .lengthening .phases .1 .and .2 .repolarization.
Which .drug .therapy .should .be .used .to .lower .the .serum .concentration .of .thyroid .hormones .and .re-
establish .eumetabolic .state .in .a .patient .with .Graves' .disease? .- .(correct .answer) .-Anti-thyroid .drugs.
Which .type .of .diuretic .would .be .used .for .a .stage .I .hypertension .in .a .patient .with .renal .insufficiency? .-
.(correct .answer) .-Loop .diuretic.
What .drug .should .be .considered .as .first-line .therapy .for .a .client .with .hypertension .and .heart .failure?
.- .(correct .answer) .-Enalapril .(Vasotec)
Which .drug .is .considered .safe .for .hypertension .treatment .during .pregnancy? .- .(correct .answer) .-
Methyldopa .(Aldomet)
What .drug .will .reduce .afterload .because .it .is .an .alpha-adrenergic .blocker? .- .(correct .answer) .-
Prazosin .(Minipress)
What .is .an .expected .effect .of .the .use .of .a .beta-adrenergic .blocker .to .control .angina? .- .(correct
.answer) .-Reduced .force .of .cardiac .contraction.
What .side .effect .should .be .monitored .closely .in .the .elderly .when .taking .Metformin .(Glucophage) .for
.type .2 .diabetes? .- .(correct .answer) .-Lactic .acidosis.
What .is .the .primary .role .of .cytochrome .p-450 .in .the .liver? .- .(correct .answer) .-Deactivate .and .detoxify
.medications .and .other .substances.
What .is .a .component .of .Vitamin .K-dependent .clotting .factors? .- .(correct .answer) .-Prothrombin
How .are .IV .morphine .and .nitroglycerin .beneficial .in .acute .heart .failure? .- .(correct .answer) .-Decrease
.preload.
What .is .the .purpose .of .administering .a .vasodilating .drug .to .a .patient .in .heart .failure? .- .(correct
.answer) .-Decrease .afterload.
What .are .some .contrindications .for .HMG-co .A .reductase .inhibitors .(statins)? .- . (correct .answer) .-They
.cause .myopathies, .especially .at .higher .doses .or .in .combination .with .certain .drugs. .They .should .never
.be .used .in .patients .taking .Warfarin .(Coumadin).
Which .drug .can .reduce .serum .LDL .the .most .in .patients .with .hyperlipidemia? .- .(correct .answer) .-
Lovastatin .(Mevacor)
Questions And Answers 2025
Why .are .nitrate-free .periods .every .24 .hours .necessary .for .the .patient .on .nitroglycerin .therapy? .-
.(correct .answer) .-To .inhibit .the .development .of .tolerance
What .does .a .low .level .of .thyroid-stimulating .hormone .indicate? .- .(correct .answer) .-Hyperthroidism
What .would .be .the .best .option .to .treat .a .newly .diagnosed .patient .with .a .low .TSH .level .with? .-
.(correct .answer) .-Propanolol .(Inderal)
Spironoaldactone .(Aldactone) .has .what .mechanism .of .action .(MOA)? .- .(correct .answer) .-Aldosterone
.antagonist
Heparin .exerts .its .therapeutic .action .by .what? .- .(correct .answer) .-Upregulating .the .activity .of .one .of
.the .body's .natural .anticoagulant .molecules, .antithrombin .III
What .physiologic .action .happens .when .the .offending .drug .is .administered .during .an .anaphylactic
.reaction. .- .(correct .answer) .-Mast .cells .liberate .large .doses .of .histamine.
What .are .two .systemic .psoriasis .medications? .- .(correct .answer) .-Photo-therapy .and .topical
.corticosteroids
What .is .the .first .choice .of .drug .therapy .for .the .majority .of .patients .with .uncomplicated .stage .I
.hypertension? .- .(correct .answer) .-Thiazide .diuretics
What .is .the .effect .of .cardiac .glycosides? .- .(correct .answer) .-Digitalis .glycosides .have .a .negative
.chronotropic .effect .on .the .cardiac .muscle .cells.
Amenorrhea .is .the .most .common .side .effect .of .which .birth .control .medication? .- .(correct .answer) .-
Medroxyprogesterone .(Depo-Provera)
What .is .an .anti-hypertensive .agent .which .competes .with .epinephrine .for .available .beta-receptor
.sites? .- .(correct .answer) .-Atenolol .(Tenormin)
, What .type .of .action .does .nitrates .have .on .the .body? .- .(correct .answer) .-Reduction .in .systemic
.venous .tone.
What .is .the .recommended .level .of .low-density .lipoprotein .cholesterol .(LDL) .for .patients .with .known
.coronary .artery .disease? .- .(correct .answer) .-100mg/dl .or .less.
What .is .the .MOA .of .group .IV .anti-dysrhythmia .drugs? .- .(correct .answer) .-Depressing .phase .4
.depolarization .and .lengthening .phases .1 .and .2 .repolarization.
Which .drug .therapy .should .be .used .to .lower .the .serum .concentration .of .thyroid .hormones .and .re-
establish .eumetabolic .state .in .a .patient .with .Graves' .disease? .- .(correct .answer) .-Anti-thyroid .drugs.
Which .type .of .diuretic .would .be .used .for .a .stage .I .hypertension .in .a .patient .with .renal .insufficiency? .-
.(correct .answer) .-Loop .diuretic.
What .drug .should .be .considered .as .first-line .therapy .for .a .client .with .hypertension .and .heart .failure?
.- .(correct .answer) .-Enalapril .(Vasotec)
Which .drug .is .considered .safe .for .hypertension .treatment .during .pregnancy? .- .(correct .answer) .-
Methyldopa .(Aldomet)
What .drug .will .reduce .afterload .because .it .is .an .alpha-adrenergic .blocker? .- .(correct .answer) .-
Prazosin .(Minipress)
What .is .an .expected .effect .of .the .use .of .a .beta-adrenergic .blocker .to .control .angina? .- .(correct
.answer) .-Reduced .force .of .cardiac .contraction.
What .side .effect .should .be .monitored .closely .in .the .elderly .when .taking .Metformin .(Glucophage) .for
.type .2 .diabetes? .- .(correct .answer) .-Lactic .acidosis.
What .is .the .primary .role .of .cytochrome .p-450 .in .the .liver? .- .(correct .answer) .-Deactivate .and .detoxify
.medications .and .other .substances.
What .is .a .component .of .Vitamin .K-dependent .clotting .factors? .- .(correct .answer) .-Prothrombin
How .are .IV .morphine .and .nitroglycerin .beneficial .in .acute .heart .failure? .- .(correct .answer) .-Decrease
.preload.
What .is .the .purpose .of .administering .a .vasodilating .drug .to .a .patient .in .heart .failure? .- .(correct
.answer) .-Decrease .afterload.
What .are .some .contrindications .for .HMG-co .A .reductase .inhibitors .(statins)? .- . (correct .answer) .-They
.cause .myopathies, .especially .at .higher .doses .or .in .combination .with .certain .drugs. .They .should .never
.be .used .in .patients .taking .Warfarin .(Coumadin).
Which .drug .can .reduce .serum .LDL .the .most .in .patients .with .hyperlipidemia? .- .(correct .answer) .-
Lovastatin .(Mevacor)
