Nurses A Pathophysiologic Approach,
7th Edition Michael P. Adams ,All
Chapters Included|| Newest Version
2026
1. Which of the following is the primary reason nurses should
understand pharmacokinetics?
a. To know the chemical structure of drugs
b. To predict drug effects and dosing schedules
c. To identify drug manufacturers
d. To memorize drug prices
b. To predict drug effects and dosing schedules
Understanding pharmacokinetics helps nurses anticipate how
drugs are absorbed, distributed, metabolized, and excreted,
guiding safe and effective administration.
2. A patient is prescribed a drug with a narrow therapeutic index.
The nurse should:
a. Encourage the patient to double the dose if a dose is missed
b. Monitor serum drug levels closely
c. Avoid monitoring since it’s safe
d. Only monitor for allergic reactions
b. Monitor serum drug levels closely
, Drugs with narrow therapeutic ranges can easily become toxic, so
monitoring serum levels is critical.
3. Which organ is primarily responsible for drug metabolism?
a. Kidneys
b. Liver
c. Lungs
d. Spleen
b. Liver
The liver contains enzymes that metabolize drugs, preparing them
for excretion.
4. A patient taking warfarin should be educated about:
a. Avoiding foods high in vitamin K
b. Increasing intake of citrus fruits
c. Doubling doses if a dose is missed
d. Stopping the drug when INR is normal
a. Avoiding foods high in vitamin K
Vitamin K can reduce the anticoagulant effect of warfarin,
increasing the risk of clotting.
5. The nurse teaches that the first-pass effect affects which route of
drug administration the most?
a. Oral
b. Intravenous
c. Intramuscular
d. Subcutaneous
a. Oral
Orally administered drugs pass through the liver before reaching
systemic circulation, reducing bioavailability.
,6. Which type of drug interaction occurs when one drug enhances
the effect of another?
a. Antagonism
b. Synergism
c. Potentiation
d. Inhibition
b. Synergism
Synergism occurs when combined drugs produce a greater effect
than each drug alone.
7. A patient reports nausea after taking a new antibiotic. This is an
example of:
a. Adverse effect
b. Side effect
c. Toxicity
d. Idiosyncratic reaction
b. Side effect
Side effects are predictable and often mild responses to a drug.
8. Which patient is at greatest risk for drug toxicity?
a. A 25-year-old male
b. A 60-year-old female with renal impairment
c. A 40-year-old healthy male
d. A 30-year-old female with a mild cold
b. A 60-year-old female with renal impairment
Impaired renal function can reduce drug excretion, increasing the
risk of toxicity.
9. What is the primary purpose of a loading dose?
a. To reduce side effects
, b. To achieve therapeutic levels quickly
c. To prevent drug interactions
d. To extend the duration of action
b. To achieve therapeutic levels quickly
Loading doses help rapidly reach the desired drug concentration in
the bloodstream.
10. Which statement about half-life is correct?
a. It is unrelated to drug dosing
b. It indicates the time for half the drug to be eliminated
c. It predicts drug allergies
d. It measures the drug’s potency
b. It indicates the time for half the drug to be eliminated
Half-life guides the timing of repeated doses to maintain
therapeutic levels.
11. A patient is prescribed digoxin. The nurse should monitor
for:
a. Hypertension
b. Bradycardia and visual disturbances
c. Hyperglycemia
d. Seizures
b. Bradycardia and visual disturbances
These are classic signs of digoxin toxicity.
12. Which class of drugs blocks beta-adrenergic receptors?
a. ACE inhibitors
b. Beta blockers
c. Calcium channel blockers
d. Diuretics